Preclinical and Clinical Development of Noncoding RNA Therapeutics for Cardiovascular Disease
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Title
Preclinical and Clinical Development of Noncoding RNA Therapeutics for Cardiovascular Disease
Authors
Keywords
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Journal
CIRCULATION RESEARCH
Volume 126, Issue 5, Pages 663-678
Publisher
Ovid Technologies (Wolters Kluwer Health)
Online
2020-02-28
DOI
10.1161/circresaha.119.315856
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Note: Only part of the references are listed.- Animal models of arrhythmia: classic electrophysiology to genetically modified large animals
- (2019) Sebastian Clauss et al. Nature Reviews Cardiology
- Dysregulated Expression of microRNA-21 and Disease Related Genes in Human Patients and Mouse Model of Alport Syndrome
- (2019) Jifan Guo et al. HUMAN GENE THERAPY
- Targeting RNA : A Transformative Therapeutic Strategy
- (2019) Wei Yin et al. CTS-Clinical and Translational Science
- MicroRNA therapy stimulates uncontrolled cardiac repair after myocardial infarction in pigs
- (2019) Khatia Gabisonia et al. NATURE
- Circular RNAs open a new chapter in cardiovascular biology
- (2019) Simona Aufiero et al. Nature Reviews Cardiology
- A Physiological Biomimetic Culture System for Pig and Human Heart Slices
- (2019) Qinghui Ou et al. CIRCULATION RESEARCH
- Non‐coding RNAs: key players in cardiac disease
- (2019) Fabian Philipp Kreutzer et al. JOURNAL OF PHYSIOLOGY-LONDON
- Circular RNAs: A Novel Class of Functional RNA Molecules with a Therapeutic Perspective
- (2019) Laura Santer et al. MOLECULAR THERAPY
- Developmental dynamics of lncRNAs across mammalian organs and species
- (2019) Ioannis Sarropoulos et al. NATURE
- RNA-based diagnostic and therapeutic strategies for cardiovascular disease
- (2019) Dongchao Lu et al. Nature Reviews Cardiology
- Biomimetic electromechanical stimulation to maintain adult myocardial slices in vitro
- (2019) Samuel A. Watson et al. Nature Communications
- The Integrative Regulatory Network of circRNA, microRNA, and mRNA in Atrial Fibrillation
- (2019) Shengyang Jiang et al. Frontiers in Genetics
- Systematic analysis of lncRNA expression profiles and atherosclerosis-associated lncRNA-mRNA network revealing functional lncRNAs in carotid atherosclerotic rabbit models
- (2019) Yingnan Wu et al. FUNCTIONAL & INTEGRATIVE GENOMICS
- Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy
- (2019) Maksymilian Prondzynski et al. EMBO Molecular Medicine
- Living myocardial slices: a novel multicellular model for cardiac translational research
- (2019) Filippo Perbellini et al. EUROPEAN HEART JOURNAL
- Circular RNA CircFndc3b modulates cardiac repair after myocardial infarction via FUS/VEGF-A axis
- (2019) Venkata Naga Srikanth Garikipati et al. Nature Communications
- A Network of Noncoding Regulatory RNAs Acts in the Mammalian Brain
- (2018) Benjamin Kleaveland et al. CELL
- H19 Induces Abdominal Aortic Aneurysm Development and Progression
- (2018) Daniel Y. Li et al. CIRCULATION
- Pluripotent Stem Cell-Derived Cardiomyocytes as a Platform for Cell Therapy Applications: Progress and Hurdles for Clinical Translation
- (2018) Angelos Oikonomopoulos et al. MOLECULAR THERAPY
- OUP accepted manuscript
- (2018) Database-The Journal of Biological Databases and Curation
- Comprehensive analysis of circRNA expression pattern and circRNA-miRNA-mRNA network in the pathogenesis of atherosclerosis in rabbits
- (2018) Feng Zhang et al. Aging-US
- Genome-wide identification of tissue-specific long non-coding RNA in three farm animal species
- (2018) Colin Kern et al. BMC GENOMICS
- A synthetic microRNA-92a inhibitor (MRG-110) accelerates angiogenesis and wound healing in diabetic and non-diabetic wounds
- (2018) Corrie L. Gallant-Behm et al. WOUND REPAIR AND REGENERATION
- Characterisation and functional predictions of canine long non-coding RNAs
- (2018) Céline Le Béguec et al. Scientific Reports
- Genome Editing of Pigs for Agriculture and Biomedicine
- (2018) Huaqiang Yang et al. Frontiers in Genetics
- Apolipoprotein E deficiency accelerates atherosclerosis development in miniature pigs
- (2018) Bin Fang et al. Disease Models & Mechanisms
- A microRNA-29 mimic (remlarsen) represses extracellular matrix expression and fibroplasia in the skin
- (2018) Corrie L. Gallant-Behm et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Circular RNAs as Therapeutic Agents and Targets
- (2018) Lesca M. Holdt et al. Frontiers in Physiology
- Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives
- (2017) Wolfgang Poller et al. EUROPEAN HEART JOURNAL
- European Society of Cardiology: Cardiovascular Disease Statistics 2017
- (2017) et al. EUROPEAN HEART JOURNAL
- Safety and activity of microRNA-loaded minicells in patients with recurrent malignant pleural mesothelioma: a first-in-man, phase 1, open-label, dose-escalation study
- (2017) Nico van Zandwijk et al. LANCET ONCOLOGY
- MicroRNA-29: A Crucial Player in Fibrotic Disease
- (2017) Zhenjun Deng et al. Molecular Diagnosis & Therapy
- The Efficacy of Cardiac Anti-miR-208a Therapy Is Stress Dependent
- (2017) Joep E.C. Eding et al. MOLECULAR THERAPY
- FDA-Approved Oligonucleotide Therapies in 2017
- (2017) Cy A. Stein et al. MOLECULAR THERAPY
- Preparation of viable adult ventricular myocardial slices from large and small mammals
- (2017) Samuel A Watson et al. Nature Protocols
- Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides
- (2017) Mark J. Graham et al. NEW ENGLAND JOURNAL OF MEDICINE
- Chemistry, mechanism and clinical status of antisense oligonucleotides and duplex RNAs
- (2017) Xiulong Shen et al. NUCLEIC ACIDS RESEARCH
- Waste disposal—An attractive strategy for cancer therapy
- (2017) Jemilat Salami et al. SCIENCE
- Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling
- (2017) Yassine Sassi et al. Nature Communications
- Genome-Wide Dynamics of Nascent Noncoding RNA Transcription in Porcine Heart After Myocardial InfarctionCLINICAL PERSPECTIVE
- (2017) Minna U. Kaikkonen et al. Circulation-Cardiovascular Genetics
- Dynamic Organization of lncRNA and Circular RNA Regulators Collectively Controlled Cardiac Differentiation in Humans
- (2017) Yongsheng Li et al. EBioMedicine
- The H19 long noncoding RNA is a novel negative regulator of cardiomyocyte hypertrophy
- (2016) Lantao Liu et al. CARDIOVASCULAR RESEARCH
- Long Noncoding RNAs in Cardiovascular Pathology, Diagnosis, and Therapy
- (2016) Christian Bär et al. CIRCULATION
- A circular RNA protects the heart from pathological hypertrophy and heart failure by targeting miR-223
- (2016) Kun Wang et al. EUROPEAN HEART JOURNAL
- Non-coding RNAs in Development and Disease: Background, Mechanisms, and Therapeutic Approaches
- (2016) Julia Beermann et al. PHYSIOLOGICAL REVIEWS
- Long noncoding RNA Chast promotes cardiac remodeling
- (2016) Janika Viereck et al. Science Translational Medicine
- A Translational Model for Diet-related Atherosclerosis
- (2016) Chidozie Amuzie et al. TOXICOLOGIC PATHOLOGY
- Human Engineered Heart Tissue: Analysis of Contractile Force
- (2016) Ingra Mannhardt et al. Stem Cell Reports
- The Circular RNA Cdr1as Promotes Myocardial Infarction by Mediating the Regulation of miR-7a on Its Target Genes Expression
- (2016) Hai-Hua Geng et al. PLoS One
- Joint Profiling of miRNAs and mRNAs Reveals miRNA Mediated Gene Regulation in the Göttingen Minipig Obesity Model
- (2016) Caroline M. Junker Mentzel et al. PLoS One
- Human Organotypic Cultured Cardiac Slices: New Platform For High Throughput Preclinical Human Trials
- (2016) C. Kang et al. Scientific Reports
- Pharmacokinetics, biodistribution and cell uptake of antisense oligonucleotides
- (2015) Richard S. Geary et al. ADVANCED DRUG DELIVERY REVIEWS
- Cardiac tissue slices: preparation, handling, and successful optical mapping
- (2015) Ken Wang et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Long Noncoding RNAs and MicroRNAs in Cardiovascular Pathophysiology
- (2015) T. Thum et al. CIRCULATION RESEARCH
- Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes: Insights Into Molecular, Cellular, and Functional Phenotypes
- (2015) I. Karakikes et al. CIRCULATION RESEARCH
- Adeno-associated virus-mediated gene therapy in cardiovascular disease
- (2015) Nadjib Hammoudi et al. CURRENT OPINION IN CARDIOLOGY
- Antisense therapy targeting apolipoprotein(a): a randomised, double-blind, placebo-controlled phase 1 study
- (2015) Sotirios Tsimikas et al. LANCET
- Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed
- (2015) Agnieszka Rybak-Wolf et al. MOLECULAR CELL
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- (2015) Xintian You et al. NATURE NEUROSCIENCE
- Factor XI Antisense Oligonucleotide for Prevention of Venous Thrombosis
- (2015) Harry R. Büller et al. NEW ENGLAND JOURNAL OF MEDICINE
- Circular RNAs are long-lived and display only minimal early alterations in response to a growth factor
- (2015) Yehoshua Enuka et al. NUCLEIC ACIDS RESEARCH
- Principles of Long Noncoding RNA Evolution Derived from Direct Comparison of Transcriptomes in 17 Species
- (2015) Hadas Hezroni et al. Cell Reports
- Adeno-Associated Viral Vectors at the Frontier between Tolerance and Immunity
- (2015) Federico Mingozzi et al. Frontiers in Immunology
- MicroRNA Profiling of Atrial Fibrillation in Canines: MiR-206 Modulates Intrinsic Cardiac Autonomic Nerve Remodeling by Regulating SOD1
- (2015) Yujiao Zhang et al. PLoS One
- Cardiac Tissue Engineering
- (2014) Marc N. Hirt et al. CIRCULATION RESEARCH
- Microvesicles as Cell–Cell Messengers in Cardiovascular Diseases
- (2014) Xavier Loyer et al. CIRCULATION RESEARCH
- ABC Transporters in Multidrug Resistance and Pharmacokinetics, and Strategies for Drug Development
- (2014) Young Choi et al. CURRENT PHARMACEUTICAL DESIGN
- Evolutionary dynamics and tissue specificity of human long noncoding RNAs in six mammals
- (2014) S. Washietl et al. GENOME RESEARCH
- Anti–microRNA-21 oligonucleotides prevent Alport nephropathy progression by stimulating metabolic pathways
- (2014) Ivan G. Gomez et al. JOURNAL OF CLINICAL INVESTIGATION
- Cardiac I-1c Overexpression With Reengineered AAV Improves Cardiac Function in Swine Ischemic Heart Failure
- (2014) Kiyotake Ishikawa et al. MOLECULAR THERAPY
- The evolution of lncRNA repertoires and expression patterns in tetrapods
- (2014) Anamaria Necsulea et al. NATURE
- Noncoding RNAs and myocardial fibrosis
- (2014) Thomas Thum Nature Reviews Cardiology
- Antisense Oligonucleotide Therapies
- (2014) Kendall S. Frazier TOXICOLOGIC PATHOLOGY
- Single Intracoronary Injection of Encapsulated Antagomir‐92a Promotes Angiogenesis and Prevents Adverse Infarct Remodeling
- (2014) Neus Bellera et al. Journal of the American Heart Association
- Macrophage MicroRNA-155 Promotes Cardiac Hypertrophy and Failure
- (2013) Stephane Heymans et al. CIRCULATION
- Inhibition of MicroRNA-92a Protects Against Ischemia/Reperfusion Injury in a Large-Animal Model
- (2013) Rabea Hinkel et al. CIRCULATION
- The Tissue-Specific lncRNA Fendrr Is an Essential Regulator of Heart and Body Wall Development in the Mouse
- (2013) Phillip Grote et al. DEVELOPMENTAL CELL
- Natural RNA circles function as efficient microRNA sponges
- (2013) Thomas B. Hansen et al. NATURE
- Decreases in Electrocardiographic R-Wave Amplitude and QT Interval Predict Myocardial Ischemic Infarction in Rhesus Monkeys with Left Anterior Descending Artery Ligation
- (2013) Xiaorong Sun et al. PLoS One
- MicroRNA-1 Accelerates the Shortening of Atrial Effective Refractory Period by Regulating KCNE1 and KCNB2 Expression: An Atrial Tachypacing Rabbit Model
- (2013) Xiaomeng Jia et al. PLoS One
- Pharmacological Inhibition of a MicroRNA Family in Nonhuman Primates by a Seed-Targeting 8-Mer AntimiR
- (2013) V. Rottiers et al. Science Translational Medicine
- Overcoming Preexisting Humoral Immunity to AAV Using Capsid Decoys
- (2013) F. Mingozzi et al. Science Translational Medicine
- Humoral Immune Response to AAV
- (2013) Roberto Calcedo et al. Frontiers in Immunology
- Functional screening identifies miRNAs inducing cardiac regeneration
- (2012) Ana Eulalio et al. NATURE
- Landscape of transcription in human cells
- (2012) Sarah Djebali et al. NATURE
- Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types
- (2012) Julia Salzman et al. PLoS One
- Circular RNAs are abundant, conserved, and associated with ALU repeats
- (2012) W. R. Jeck et al. RNA
- The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy
- (2012) Ahmet Ucar et al. Nature Communications
- Therapeutic Inhibition of miR-208a Improves Cardiac Function and Survival During Heart Failure
- (2011) Rusty L. Montgomery et al. CIRCULATION
- Inhibition of miR-15 Protects Against Cardiac Ischemic Injury
- (2011) Thomas G. Hullinger et al. CIRCULATION RESEARCH
- Adeno-Associated Virus Antibody Profiles in Newborns, Children, and Adolescents
- (2011) Roberto Calcedo et al. Clinical and Vaccine Immunology
- Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses
- (2011) M. N. Cabili et al. GENES & DEVELOPMENT
- Animal Models of Cardiovascular Diseases
- (2011) Carlos Zaragoza et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Cardiomyocytes derived from human embryonic and induced pluripotent stem cells: comparative ultrastructure
- (2011) Mihaela Gherghiceanu et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Antagonism of miR-33 in mice promotes reverse cholesterol transport and regression of atherosclerosis
- (2011) Katey J. Rayner et al. JOURNAL OF CLINICAL INVESTIGATION
- Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides
- (2011) Katey J. Rayner et al. NATURE
- MicroRNA-328 Contributes to Adverse Electrical Remodeling in Atrial Fibrillation
- (2010) Yanjie Lu et al. CIRCULATION
- MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis
- (2010) S. H. Najafi-Shoushtari et al. SCIENCE
- MiR-33 Contributes to the Regulation of Cholesterol Homeostasis
- (2010) K. J. Rayner et al. SCIENCE
- Downregulation of miR-133 and miR-590 contributes to nicotine-induced atrial remodelling in canines
- (2009) Hongli Shan et al. CARDIOVASCULAR RESEARCH
- Tissue Slices from Adult Mammalian Hearts as a Model for Pharmacological Drug Testing
- (2009) Alexandra Bussek et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- miR-1 Overexpression Enhances Ca 2+ Release and Promotes Cardiac Arrhythmogenesis by Targeting PP2A Regulatory Subunit B56α and Causing CaMKII-Dependent Hyperphosphorylation of RyR2
- (2009) Dmitry Terentyev et al. CIRCULATION RESEARCH
- Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells
- (2009) Jianhua Zhang et al. CIRCULATION RESEARCH
- MicroRNA-15b Modulates Cellular ATP Levels and Degenerates Mitochondria via Arl2 in Neonatal Rat Cardiac Myocytes
- (2009) Hitoo Nishi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Profiling Muscle-Specific MicroRNA Expression after Peripheral Denervation and Reinnervation in a Rat Model
- (2009) Seng-Feng Jeng et al. JOURNAL OF NEUROTRAUMA
- MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice
- (2009) A. Bonauer et al. SCIENCE
- MicroRNA-206 Delays ALS Progression and Promotes Regeneration of Neuromuscular Synapses in Mice
- (2009) A. H. Williams et al. SCIENCE
- MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
- (2008) Thomas Thum et al. NATURE
- Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis
- (2008) E. van Rooij et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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