Article
Agriculture, Dairy & Animal Science
Davide Di Paola, Enrico Gugliandolo, Fabiano Capparucci, Marika Cordaro, Carmelo Iaria, Rosalba Siracusa, Ramona D'Amico, Roberta Fusco, Daniela Impellizzeri, Salvatore Cuzzocrea, Rosanna Di Paola, Rosalia Crupi, Alessio Filippo Peritore
Summary: Simultaneous exposure to multiple contaminants can increase fish toxicity, and co-exposure to cadmium and imidacloprid can cause developmental damage and harm to retinal cells in zebrafish, potentially leading to apoptosis.
Review
Biochemistry & Molecular Biology
Cristina Pagano, Giovanna Navarra, Laura Coppola, Beatrice Savarese, Giorgio Avilia, Antonella Giarra, Giovanni Pagano, Alessandra Marano, Marco Trifuoggi, Maurizio Bifulco, Chiara Laezza
Summary: Pollutants, including direct and indirect mutagens, can increase the risk of tumorigenesis. The rising incidence of brain tumors has sparked interest in studying pollutants found in food, air, and water supply. These compounds chemically alter biological molecules in the body, leading to harmful effects and an increased risk of pathologies like cancer. This review aims to discuss the impact of environmental carcinogens on brain tumorigenesis risk, focusing on specific categories of pollutants and their sources.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Fisheries
Ali Raza Jahejo, Fa-jie Jia, Sayed Haidar Abbas Raza, Mujahid Ali Shah, Jiao-jiao Yin, Anam Ahsan, Muhammad Waqas, Sheng Niu, Guan-bao Ning, Ding Zhang, Ajab Khan, Wen-xia Tian
Summary: Genes related to the Toll-like receptors (TLRs) signaling pathway showed significant differences in expression after being induced by disease, and the rGSTA3 protein was found to prevent chondrocyte death.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
Tomasz Suchocki, Bartosz Czech, Aleksandra Dunislawska, Anna Slawinska, Natalia Derebecka, Joanna Wesoly, Maria Siwek, Joanna Szyda
Summary: In this study, single nucleotide polymorphisms (SNPs) with significant impacts on antibody response were identified using a SNP prioritization method in F2 experimental individuals created by crossing Green-legged Partridgelike and White Leghorn. SNPs located in specific genomic regions were pre-targeted based on literature references and database information. The analysis revealed that certain SNPs, particularly located on GGA2 in the MYD88 gene, played a crucial role in determining antibody response.
Article
Environmental Sciences
Lucia Rodriguez-Lopez, Vanesa Santas-Miguel, Raquel Cela-Dablanca, Avelino Nunez-Delgado, Esperanza Alvarez-Rodriguez, Andres Rodriguez-Seijo, Manuel Arias-Estevez
Summary: Antibiotics pollution is a growing concern in the environment, with high levels of these compounds being found in soil, water, and sediments. This study investigates the adsorption/desorption processes of the macrolide antibiotic clarithromycin (CLA) in different agricultural soils, highlighting the influence of various soil characteristics. The results show varying levels of CLA adsorption, with the silt fraction content and exchangeable Ca content having the strongest influence. Desorption was found to be lower than adsorption, with factors such as total nitrogen, organic carbon, and exchangeable Ca and Mg contents influencing the process. pH values did not significantly impact the adsorption/desorption process. These findings can be used to develop effective strategies to mitigate the presence of antibiotics in the environment.
ENVIRONMENTAL RESEARCH
(2023)
Article
Chemistry, Physical
Sufei Wang, Yang Li, Qing Liu, Jingyi Wang, Yujie Zhao, Yawen Cai, Hua Li, Zhongshan Chen
Summary: With the development of industry and agriculture, large amounts of pollutants are released to the natural environment, posing a threat to human health. This review summarizes recent studies on the degradation of organic pollutants and the reduction of metal radionuclides/ions through catalytic processes. Various catalytic techniques for the elimination of environmental pollutants are discussed, with a focus on the role of free active radicals. The relationship between pollutant properties, catalyst structures, and environmental conditions is also explored.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2023)
Review
Microbiology
Samradhi Singh, Poonam Sharma, Namrata Pal, Manoj Kumawat, Swasti Shubham, Devojit Kumar Sarma, Rajnarayan R. Tiwari, Manoj Kumar, Ravinder Nagpal
Summary: In recent years, the microbiome has become a high-priority research area for uncovering the connection between brain health and gut dysbiosis. Through metabolites produced by the microbiome and the involvement of various systems, the gut microbiome plays a crucial role in regulating the gut-brain axis. Environmental pollutants may impact the communication between gut microbes and the brain, potentially leading to neurological and psychiatric disorders.
Article
Cell Biology
Carolina Duarte-Hospital, Arnaud Tete, Francois Brial, Louise Benoit, Meriem Koual, Celine Tomkiewicz, Min Ji Kim, Etienne B. Blanc, Xavier Coumoul, Sylvie Bortoli
Summary: Environmental factors have a significant impact on human health, including diet, sedentary lifestyle, and exposure to pollutants. The cellular and molecular events triggered by exposure to environmental pollutants vary greatly depending on age, chronicity, and exposure doses. Mitochondrial dysfunction is increasingly recognized as a major characteristic of environmental damage. This article reviews the multiple mechanisms by which pollutants cause mitochondrial toxicity in relation to chronic diseases and proposes the Aryl hydrocarbon Receptor (AhR) as an exposome receptor model that activates various toxic events through mitochondrial dysfunction. Finally, some remarks are provided on mitotoxicity and risk assessment.
Review
Chemistry, Multidisciplinary
Guo-Li Yang, Xiao-Lei Jiang, Hang Xu, Bin Zhao
Summary: Environmental pollution poses serious health risks and requires the urgent detection of pollutants for protection. Luminescent metal-organic frameworks (LMOFs) with tunable structures have shown excellent performance as sensors for detecting various environmental pollutants.
Review
Environmental Sciences
Tatiana Duque-Cartagena, Eduardo Mundstock, Marcello Dala Dalla Bernardina, Alexandre Vontobel Padoin, Wilson Canon-Montanez, Rita Mattiello
Summary: The effect of environmental pollution on human health is significant, leading to higher mortality and morbidity rates. This study aimed to explore the impact of pollutants on various measures of body composition. The findings suggest that endocrine-disrupting chemicals, such as dioxins, furans, PCBs, and pesticides, are associated with changes in body composition, particularly waist circumference and the sum of four skinfolds.
ENVIRONMENTAL RESEARCH
(2023)
Article
Chemistry, Physical
Ze Jian, Maximilian Heide, Nianjun Yang, Carsten Engelhard, Xin Jiang
Summary: The efficient electrocatalytic degradation of environmental pollutants is achieved by synthesizing diamond fibers (DFs) with a large surface area and high peak current density as the electrode. DFs can effectively degrade organic pollutants in a short period of time due to their unique structure combining boron dopped diamond film and carbon fibers.
Article
Neurosciences
Ajay Yadav, Steven Verhaegen, Mussie Ghezu Hadera, Hanne Friis Berntsen, Vidar Berg, Jan Ludvig Lyche, Azemira Sabaredzovic, Line Smastuen Haug, Oddvar Myhre, Karin Elisabeth Zimmer, Ragnhild Elisabeth Paulsen, Erik Ropstad, Fernando Boix
Summary: Persistent organic pollutants (POPs) were found to reach the fetal brain, with differences observed in the distribution speed between different compounds. PFASs displayed slow elimination and high persistence in the brain, while OCPs and PCBs showed high levels relative to the dose administrated. Chicken embryos proved to be a suitable model for studying the distribution of POPs in the developing brain.
Article
Environmental Sciences
Mayank Gupta, Tejasvi Chauhan, Raghu Murtugudde, Subimal Ghosh
Summary: The dynamics of interactions between environmental and meteorological variables in urban regions are complex due to continuously evolving coupled human-natural processes. Analysis indicates that pollutant concentration dynamics drive interactions between variables in the urban meteorological system, especially during the COVID-19 lockdown period.
ENVIRONMENTAL RESEARCH LETTERS
(2021)
Review
Environmental Sciences
Sheng Yang, Zaozao Chen, Yanping Cheng, Tong Liu, Lihong Yin, Yuepu Pu, Geyu Liang
Summary: Environmental pollution poses a serious threat to human health, highlighting the importance of rapidly and efficiently evaluating environmental pollutants. The development of organ-on-a-chip systems offers new opportunities for screening environmental pollutants, providing a comparable microenvironment and realistic response capabilities.
ENVIRONMENTAL POLLUTION
(2021)
Review
Immunology
Teresa Balbi, Manon Auguste, Caterina Ciacci, Laura Canesi
Summary: Studies have identified marine bivalves as a key group for studying immunological responses to pollutant exposure, with the need for measuring immune biomarkers in hemocytes and hemolymph to evaluate overall impact. Utilizing cutting-edge technology such as -omics can reveal the complexity of immune responses and help understand the mechanisms behind immune dysfunction induced by pollutants. Integrating different approaches can contribute to knowledge on sensitivity of bivalve species to multiple stressors and their susceptibility to disease.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Environmental Sciences
Yu Wang, Hongjing Zhao, Yizhi Shao, Juanjuan Liu, Jinglun Li, Liyang Luo, Mingwei Xing
Article
Immunology
Juanjuan Liu, Hongjing Zhao, Yu Wang, Yizhi Shao, Lina Zhang, Mingwei Xing
INTERNATIONAL IMMUNOPHARMACOLOGY
(2018)
Article
Environmental Sciences
Juanjuan Liu, Hongjing Zhao, Yu Wang, Yizhi Shao, Hui Zong, Xiangwei Zeng, Mingwei Xing
Article
Biochemistry & Molecular Biology
Xin Yang, Hongjing Zhao, Yu Wang, Juanjuan Liu, Menghao Guo, Dongxue Fei, Mengyao Mu, Mingwei Xing
BIOLOGICAL TRACE ELEMENT RESEARCH
(2020)
Article
Environmental Sciences
Dongxue Fei, Hongjing Zhao, Yu Wang, Juanjuan Liu, Mengyao Mu, Menghao Guo, Xin Yang, Mingwei Xing
Article
Fisheries
Hongjing Zhao, Yu Wang, Xin Yang, Dongxue Fei, Mengyao Mu, Menghao Guo, Hongxian Yu, Mingwei Xing
FISH & SHELLFISH IMMUNOLOGY
(2019)
Article
Environmental Sciences
Hongjing Zhao, Yu Wang, Menghao Guo, Dongxue Fei, Menghao Mu, Hongxian Yu, Mingwei Xing
Article
Engineering, Environmental
Yu Wang, Hongjing Zhao, Menghao Guo, Dongxue Fei, Lina Zhang, Mingwei Xing
JOURNAL OF HAZARDOUS MATERIALS
(2020)
Article
Engineering, Environmental
Hongjing Zhao, Yu Wang, Yachen Liu, Kai Yin, Dongxu Wang, Baoying Li, Hongxian Yu, Mingwei Xing
Summary: The study focused on the toxic effects of Cypermethrin on grass carp, showing hepatotoxicity in terms of pathological changes, oxidative stress, and apoptosis in the liver. RNA-Seq analysis suggested that proteasome and oxidative phosphorylation pathways were compromised under CMN exposure, leading to toxic effects. In vitro studies further confirmed that proteasome pathway inhibition could protect against CMN-induced toxicity by enhancing antioxidative and anti-inflammatory capability.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Kai Yin, Hongmin Lu, Yue Zhang, Lulu Hou, Xin Meng, Junbo Li, Hongjing Zhao, Mingwei Xing
Summary: Microplastics, unlike regular pollutants, cannot dissolve in liquids. Physical contact with tissue can damage tissue structure, and cerebral ischemia may be a main way in which brain tissue is affected by microplastics. Inflammatory response plays a significant role in this process.
CHEMICO-BIOLOGICAL INTERACTIONS
(2022)
Article
Environmental Sciences
Hongmin Lu, Kai Yin, Heng Su, Dongxu Wang, Yue Zhang, Lulu Hou, Jun Bo Li, Yu Wang, Mingwei Xing
Summary: This study found that polystyrene microplastics (PS-MPs) can cause lung injury in broiler chickens, leading to oxidative stress through inhibition of the PTEN/PI3K/AKT pathway and induction of autophagy and cell apoptosis. These results are of great significance to the toxicological study of PS-MPs and the protection of the ecosystem.
ENVIRONMENTAL TOXICOLOGY
(2023)
Article
Engineering, Environmental
Kai Yin, Dongxu Wang, Yue Zhang, Hongmin Lu, Lulu Hou, Tiantian Guo, Hongjing Zhao, Mingwei Xing
Summary: Microplastics, a new and increasing environmental pollutant, induce liver inflammation and the formation of macrophage extracellular traps (METs). Macrophages actively phagocytose microplastics, leading to elevated ROS levels, disruption of mitochondrial homeostasis, activation of mitochondrial autophagy and lysosomes, and eventually lysosome rupture and release of calcium ions to induce METs formation.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Hongjing Zhao, Yu Wang, Mengyao Mu, Menghao Guo, Hongxian Yu, Mingwei Xing
Article
Biochemistry & Molecular Biology
Yu Wang, Hongjing Zhao, Menghao Guo, Yizhi Shao, Juanjuan Liu, Guangshun Jiang, Mingwei Xing