Fluorohalogenation of gem ‐Difluoroalkenes: Synthesis and Applications of α‐Trifluoromethyl Halides

Hydrogen Bonding Phase-Transfer Catalysis with Potassium Fluoride: Enantioselective Synthesis of β-Fluoroamines

(2019) Gabriele Pupo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Synthesis of α-Trifluoromethyl Carboxylic Acids and Esters via Fluorocarboxylation of gem-Difluoroalkenes

(2019) Woo-Jin Yoo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Photoredox-Coupled F-Nucleophilic Addition: Allylation of gem -Difluoroalkenes

(2019) Haidong Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic, Enantioselective 1,2-Difluorination of Cinnamamides

(2019) Moriana K. Haj et al.   ORGANIC LETTERS

Sulfonyl Fluoride Synthesis through Electrochemical Oxidative Coupling of Thiols and Potassium Fluoride

(2019) Gabriele Laudadio et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereochemical Revision, Total Synthesis, and Solution State Conformation of the Complex Chlorosulfolipid Mytilipin B

(2019) Philipp Sondermann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organotitanium Nucleophiles in Asymmetric Cross-Coupling Reaction: Stereoconvergent Synthesis of Chiral α-CF3 Thioethers

(2019) Andrii Varenikov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Facilitating the transmetalation step with aryl-zincates in nickel-catalyzed enantioselective arylation of secondary benzylic halides

(2019) Weichen Huang et al.   Nature Communications

Catalytic Enantioselective Dihalogenation in Total Synthesis

(2018) Matthew L. Landry et al.   ACCOUNTS OF CHEMICAL RESEARCH

Stille cross-coupling of secondary and tertiary α-(trifluoromethyl)-benzyl chlorides with allylstannanes

(2018) Nagender Punna et al.   CHEMICAL COMMUNICATIONS

Trifluoromethyl Benzoate: A Versatile Trifluoromethoxylation Reagent

(2018) Min Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric nucleophilic fluorination under hydrogen bonding phase-transfer catalysis

(2018) Gabriele Pupo et al.   SCIENCE

Enantioselective, Catalytic Vicinal Difluorination of Alkenes

(2018) Felix Scheidt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

F– Nucleophilic-Addition-Induced [3 + 2] Annulation: Direct Access to CF3-Substituted Indenes

(2018) Hai-Jun Tang et al.   ORGANIC LETTERS

Mechanism and Origins of Chemo- and Stereoselectivities of Aryl Iodide-Catalyzed Asymmetric Difluorinations of β-Substituted Styrenes

(2018) Biying Zhou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Synthesis of α-Trifluoromethyl Benzylic Amines via Fluoroarylation of gem-Difluoro-2-azadienes Enabled by Phosphine-Catalyzed Formation of an Azaallyl–Silver Intermediate

(2018) Paige E. Daniel et al.   ACS Catalysis

Highly Regio- and Enantioselective Vicinal Dihalogenation of Allyl Amides

(2017) Bardia Soltanzadeh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantiospecific Solvolytic Functionalization of Bromochlorides

(2017) Alexander J. Burckle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective Halogenation in Natural Product Synthesis

(2016) Won-jin Chung et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

F– Nucleophilic-Addition-Induced Allylic Alkylation

(2016) Panpan Tian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Difluorination of Olefins

(2016) István Gábor Molnár et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic, Diastereoselective 1,2-Difluorination of Alkenes

(2016) Steven M. Banik et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Enantioselective Dihalogenation and the Selective Synthesis of (−)-Deschloromytilipin A and (−)-Danicalipin A

(2016) Matthew L. Landry et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Mediated Trifluoromethylthiolation–Iodination of Arynes

(2016) Yuwen Zeng et al.   ORGANIC LETTERS

Nickel-Catalyzed Alkyl-Alkyl Cross-Couplings of Fluorinated Secondary Electrophiles: A General Approach to the Synthesis of Compounds having a Perfluoroalkyl Substituent

(2015) Yufan Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biological Investigations of (+)-Danicalipin A Enabled Through Synthesis

(2015) Adrian M. Bailey et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic, Stereoselective Dihalogenation of Alkenes: Challenges and Opportunities

(2015) Alexander J. Cresswell et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Crown ether metal complex fluoride salt as a facile and low hygroscopic fluoride source for nucleophilic fluorination

(2015) Vinod H. Jadhav et al.   CHEMICAL ENGINEERING JOURNAL

Monofluorination of Organic Compounds: 10 Years of Innovation

(2015) Pier Alexandre Champagne et al.   CHEMICAL REVIEWS

Carbon Trifluoromethylation Reactions of Hydrocarbon Derivatives and Heteroarenes

(2015) Concepción Alonso et al.   CHEMICAL REVIEWS

Catalytic Chemo-, Regio-, and Enantioselective Bromochlorination of Allylic Alcohols

(2015) Dennis X. Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Selective Synthesis of Halomon, Plocamenone, and Isoplocamenone

(2015) Cyril Bucher et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoconvergent Negishi Arylations of Racemic Secondary Alkyl Electrophiles: Differentiating between a CF3 and an Alkyl Group

(2015) Yufan Liang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Approaches to the Chemical Synthesis of the Chlorosulfolipids

(2014) Won-Jin Chung et al.   ACCOUNTS OF CHEMICAL RESEARCH

Haloalkynes: A Powerful and Versatile Building Block in Organic Synthesis

(2014) Wanqing Wu et al.   ACCOUNTS OF CHEMICAL RESEARCH

AgF-Mediated Fluorinative Cross-Coupling of Two Olefins: Facile Access to α-CF3Alkenes and β-CF3Ketones

(2014) Bing Gao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modern Carbon–Fluorine Bond Forming Reactions for Aryl Fluoride Synthesis

(2014) Michael G. Campbell et al.   CHEMICAL REVIEWS

Good Partnership between Sulfur and Fluorine: Sulfur-Based Fluorination and Fluoroalkylation Reagents for Organic Synthesis

(2014) Chuanfa Ni et al.   CHEMICAL REVIEWS

Trifluoromethyltrimethylsilane: Nucleophilic Trifluoromethylation and Beyond

(2014) Xiao Liu et al.   CHEMICAL REVIEWS

Electrophilic Trifluoromethylation by Use of Hypervalent Iodine Reagents

(2014) Julie Charpentier et al.   CHEMICAL REVIEWS

Vicinal Difunctionalization of Alkenes with Iodine(III) Reagents and Catalysts

(2014) R. Martín Romero et al.   Chemistry-An Asian Journal

Recent advances in stereoselective bromofunctionalization of alkenes using N-bromoamide reagents

(2013) Chong Kiat Tan et al.   CHEMICAL COMMUNICATIONS

Silver-Mediated Trifluoromethylation–Iodination of Arynes

(2013) Yuwen Zeng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Enantioselective Dibromination of Allylic Alcohols

(2013) Dennis X. Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

AgF-Mediated Fluorinative Homocoupling of gem-Difluoroalkenes

(2013) Bing Gao et al.   ORGANIC LETTERS

Silver-Assisted Difunctionalization of Terminal Alkynes: Highly Regio- and Stereoselective Synthesis of Bromofluoroalkenes

(2012) Yibiao Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Catalytic, Asymmetric Halofunctionalization of Alkenes-A Critical Perspective

(2012) Scott E. Denmark et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in the Total Synthesis of Chlorosulfolipids

(2012) Christian Nilewski et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Three-Component Coupling of Arynes and Organic Bromides

(2011) Hiroto Yoshida et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A simple, rapid procedure for nucleophilic radiosynthesis of aliphatic [18F]trifluoromethyl groups

(2011) Patrick J. Riss et al.   CHEMICAL COMMUNICATIONS

Impact of fluorine substituents on the rates of nucleophilic aliphatic substitution and β-elimination

(2011) Henry Martinez et al.   JOURNAL OF FLUORINE CHEMISTRY

Enantioselective Dichlorination of Allylic Alcohols

(2011) K. C. Nicolaou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalysis for fluorination and trifluoromethylation

(2011) Takeru Furuya et al.   NATURE

Asymmetric Construction of Stereogenic Carbon Centers Featuring a Trifluoromethyl Group from Prochiral Trifluoromethylated Substrates

(2010) Jing Nie et al.   CHEMICAL REVIEWS

Enantioselective Total Synthesis of (−)-Napyradiomycin A1 via Asymmetric Chlorination of an Isolated Olefin

(2009) Scott A. Snyder et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of 2-aryl-3,3,3-trifluoropropanoic acids using electrochemical carboxylation of (1-bromo-2,2,2-trifluoroethyl)arenes and its application to the synthesis of β,β,β-trifluorinated non-steroidal anti-inflammatory drugs

(2009) Yusuke Yamauchi et al.   TETRAHEDRON

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS