Silencing of circFoxO3 Protects HT22 Cells from Glutamate-Induced Oxidative Injury via Regulating the Mitochondrial Apoptosis Pathway

LZ-101, a novel derivative of danofloxacin, induces mitochondrial apoptosis by stabilizing FOXO3a via blocking autophagy flux in NSCLC cells

(2019) Yongjian Guo et al.   Cell Death & Disease

A Novel Indolizine Derivative Induces Apoptosis Through the Mitochondria p53 Pathway in HepG2 Cells

(2019) Yushuang Liu et al.   Frontiers in Pharmacology

Circular RNAs: Biogenesis, Mechanism, and Function in Human Cancers

(2019) Xing Zhao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Circular RNA circ-ZKSCAN1 inhibits bladder cancer progression through miR-1178-3p/p21 axis and acts as a prognostic factor of recurrence

(2019) Junming Bi et al.   Molecular Cancer

Highly Dynamic Changes in the Activity and Regulation of Macroautophagy in Hearts Subjected to Increased Proteotoxic Stress

(2019) Bo Pan et al.   Frontiers in Physiology

Neuroprotective effect of Annona glabra extract against ethanol-induced apoptotic neurodegeneration in neonatal rats

(2018) Hongru Ma et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Protective effect of mitochondrial-targeted antioxidant MitoQ against iron ion 56 Fe radiation induced brain injury in mice

(2018) Lu Gan et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Artemisinin Prevents Glutamate-Induced Neuronal Cell Death Via Akt Pathway Activation

(2018) Shao-Peng Lin et al.   Frontiers in Cellular Neuroscience

SK channel activation is neuroprotective in conditions of enhanced ER–mitochondrial coupling

(2018) Birgit Honrath et al.   Cell Death & Disease

Leptin Maintained Zinc Homeostasis Against Glutamate-Induced Excitotoxicity by Preventing Mitophagy-Mediated Mitochondrial Activation in HT22 Hippocampal Neuronal Cells

(2018) Mei-fang Jin et al.   Frontiers in Neurology

The Therapeutic Potential of Metformin in Neurodegenerative Diseases

(2018) Carola Rotermund et al.   Frontiers in Endocrinology

TFEB activation protects against cardiac proteotoxicity via increasing autophagic flux

(2017) Bo Pan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Aging, Metabolism, and Cancer Development: from Peto’s Paradox to the Warburg Effect

(2017) Tia R. Tidwell et al.   Aging and Disease

IL-17A Enhances Microglial Response to OGD by Regulating p53 and PI3K/Akt Pathways with Involvement of ROS/HMGB1

(2017) Bin Zhang et al.   Frontiers in Molecular Neuroscience

Artemisinin protects PC12 cells against β-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway

(2017) Zhiwen Zeng et al.   Redox Biology

Foxo3 circular RNA promotes cardiac senescence by modulating multiple factors associated with stress and senescence responses

(2016) William W. Du et al.   EUROPEAN HEART JOURNAL

Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2

(2016) William W. Du et al.   NUCLEIC ACIDS RESEARCH

Aging and Neurodegeneration: A Tangle of Models and Mechanisms

(2016) Sasanka Chakrabarti et al.   Aging and Disease

Death Receptor 6 and Caspase-6 Regulate Prion Peptide-Induced Axonal Degeneration in Rat Spinal Neurons

(2015) Yunsheng Wang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

STI571 protects neuronal cells from neurotoxic prion protein fragment-induced apoptosis

(2015) Yaoqian Pan et al.   NEUROPHARMACOLOGY

Foxo3 activity promoted by non-coding effects of circular RNA and Foxo3 pseudogene in the inhibition of tumor growth and angiogenesis

(2015) W Yang et al.   ONCOGENE

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

c-Abl Tyrosine Kinase Mediates Neurotoxic Prion Peptide-Induced Neuronal Apoptosis via Regulating Mitochondrial Homeostasis

(2014) Bo Pan et al.   MOLECULAR NEUROBIOLOGY

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

From pseudo-ceRNAs to circ-ceRNAs: a tale of cross-talk and competition

(2013) Riccardo Taulli et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY