Death Receptor 6 and Caspase-6 Regulate Prion Peptide-Induced Axonal Degeneration in Rat Spinal Neurons

Sarm1-Mediated Axon Degeneration Requires Both SAM and TIR Interactions

(2013) J. Gerdts et al.   JOURNAL OF NEUROSCIENCE

Death receptor 6 (DR6) antagonist antibody is neuroprotective in the mouse SOD1G93A model of amyotrophic lateral sclerosis

(2013) G Huang et al.   Cell Death & Disease

A DR6/p75NTR complex is responsible for β-amyloid-induced cortical neuron death

(2013) Y Hu et al.   Cell Death & Disease

Distinct pathways mediate axon degeneration during apoptosis and axon-specific pruning

(2013) Corey L. Cusack et al.   Nature Communications

Rescue from excitotoxicity and axonal degeneration accompanied by age-dependent behavioral and neuroanatomical alterations in caspase-6-deficient mice

(2012) Valeria Uribe et al.   HUMAN MOLECULAR GENETICS

The NALP3 inflammasome is involved in neurotoxic prion peptide-induced microglial activation

(2012) Fushan Shi et al.   Journal of Neuroinflammation

A Caspase Cascade Regulating Developmental Axon Degeneration

(2012) D. J. Simon et al.   JOURNAL OF NEUROSCIENCE

Death receptor 6 negatively regulates oligodendrocyte survival, maturation and myelination

(2011) Sha Mi et al.   NATURE MEDICINE

Amyloid Precursor Protein Cleavage-Dependent and -Independent Axonal Degeneration Programs Share a Common Nicotinamide Mononucleotide Adenylyltransferase 1-Sensitive Pathway

(2010) B. P. S. Vohra et al.   JOURNAL OF NEUROSCIENCE

Degenerating Synaptic Boutons in Prion Disease

(2009) Zuzana Šišková et al.   AMERICAN JOURNAL OF PATHOLOGY

APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

(2009) Anatoly Nikolaev et al.   NATURE

Microtubule assembly, organization and dynamics in axons and dendrites

(2009) Cecilia Conde et al.   NATURE REVIEWS NEUROSCIENCE

Selective presynaptic degeneration in the synaptopathy associated with ME7-induced hippocampal pathology

(2009) Bryony C. Gray et al.   NEUROBIOLOGY OF DISEASE

PrP(106-126) Does Not Interact with Membranes under Physiological Conditions

(2008) Sónia Troeira Henriques et al.   BIOPHYSICAL JOURNAL

Signaling by death receptors in the nervous system

(2008) Georg Haase et al.   CURRENT OPINION IN NEUROBIOLOGY

Targets of Caspase-6 Activity in Human Neurons and Alzheimer Disease

(2008) Guy Klaiman et al.   MOLECULAR & CELLULAR PROTEOMICS