Platelet and immune characteristics of immune thrombocytopaenia patients non-responsive to therapy reveal severe immune dysregulation

Platelet Apoptosis and PAI-1 are Involved in the Pro-Coagulant State of Immune Thrombocytopaenia Patients Treated with Thrombopoietin Receptor Agonists

(2019) Raul Justo Sanz et al.   THROMBOSIS AND HAEMOSTASIS

Thrombopoietin receptor agonist (TPO-RA) treatment raises platelet counts and reduces anti-platelet antibody levels in mice with immune thrombocytopenia (ITP)

(2019) Rick Kapur et al.   PLATELETS

Immune Thrombocytopenia

(2019) Nichola Cooper et al.   NEW ENGLAND JOURNAL OF MEDICINE

Platelet Function in ITP, Independent of Platelet Count, Is Consistent Over Time and Is Associated with Both Current and Subsequent Bleeding Severity

(2018) R. Grace et al.   THROMBOSIS AND HAEMOSTASIS

Multirefractory primary immune thrombocytopenia; targeting the decreased sialic acid content

(2018) Nuria Revilla et al.   PLATELETS

Effect of thrombopoietin receptor agonists on markers of coagulation and P-selectin in patients with immune thrombocytopenia

(2017) Lamya Garabet et al.   PLATELETS

Pathogenesis and Therapeutic Mechanisms in Immune Thrombocytopenia (ITP)

(2017) Anne Zufferey et al.   Journal of Clinical Medicine

Thrombopoietin receptor agonists shift the balance of Fcγ receptors toward inhibitory receptor IIb on monocytes in ITP

(2016) Xin-guang Liu et al.   BLOOD

Investigation of platelet apoptosis in adult patients with chronic immune thrombocytopenia

(2016) Gang Deng et al.   Hematology

Effect of thrombopoietin-receptor agonists on circulating cytokine and chemokine levels in patients with primary immune thrombocytopenia (ITP)

(2016) Sif Gudbrandsdottir et al.   PLATELETS

Glycans and the platelet life cycle

(2016) Renhao Li et al.   PLATELETS

Sialic acid-modified antigens impose tolerance via inhibition of T-cell proliferation and de novo induction of regulatory T cells

(2016) Maurizio Perdicchio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Platelet clearance by the hepatic Ashwell-Morrell receptor: mechanisms and biological significance

(2016) Karin M. Hoffmeister et al.   THROMBOSIS RESEARCH

Platelet Apoptosis in Adult Immune Thrombocytopenia: Insights into the Mechanism of Damage Triggered by Auto-Antibodies

(2016) Nora P. Goette et al.   PLoS One

Nouvelle Cuisine: Platelets Served with Inflammation

(2015) Rick Kapur et al.   JOURNAL OF IMMUNOLOGY

Severe bleeding events in adults and children with primary immune thrombocytopenia: a systematic review

(2015) C. Neunert et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia

(2015) June Li et al.   Nature Communications

The role of apoptosis in megakaryocytes and platelets

(2014) Benjamin T. Kile   BRITISH JOURNAL OF HAEMATOLOGY

Alterations in immune cell subsets and their cytokine secretion profile in childhood idiopathic thrombocytopenic purpura (ITP)

(2014) R. M. Talaat et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Association of autoantibody specificity and response to intravenous immunoglobulin G therapy in immune thrombocytopenia: a multicenter cohort study

(2014) J. Peng et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Glycoprotein Ibα clustering induces macrophage-mediated platelet clearance in the liver

(2014) R. Yan et al.   THROMBOSIS AND HAEMOSTASIS

Cellular immune dysfunction in immune thrombocytopenia (ITP)

(2013) Christopher G. J. McKenzie et al.   BRITISH JOURNAL OF HAEMATOLOGY

Platelet apoptosis and agonist-mediated activation in myelodysplastic syndromes

(2013) Víctor Jiménez-Yuste et al.   THROMBOSIS AND HAEMOSTASIS

Elevated NKT cell levels in adults with severe chronic immune thrombocytopenia

(2013) RUILONG XU et al.   Experimental and Therapeutic Medicine

CD16+ monocytes control T-cell subset development in immune thrombocytopenia

(2012) H. Zhong et al.   BLOOD

Relative efficacy of steroid therapy in immune thrombocytopenia mediated by anti-platelet GPIIbIIIa versus GPIbα antibodies

(2011) Qingshu Zeng et al.   AMERICAN JOURNAL OF HEMATOLOGY

Improved regulatory T-cell activity in patients with chronic immune thrombocytopenia treated with thrombopoietic agents

(2010) W. Bao et al.   BLOOD

Th1 (CXCL10) and Th2 (CCL2) chemokine expression in patients with immune thrombocytopenia

(2010) Dongsheng Gu et al.   HUMAN IMMUNOLOGY

Standardization of terminology, definitions and outcome criteria in immune thrombocytopenic purpura of adults and children: report from an international working group

(2008) F. Rodeghiero et al.   BLOOD

Matrix metalloproteinase 9 is involved in Crohn's disease-associated platelet hyperactivation through the release of soluble CD40 ligand

(2008) L Menchen et al.   GUT