- Home
- Publications
- Publication Search
- Publication Details
Title
Medulloblastoma genomics in the modern molecular era
Authors
Keywords
-
Journal
BRAIN PATHOLOGY
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2019-12-04
DOI
10.1111/bpa.12804
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The lysine‐specific methyltransferase KMT2C/MLL3 regulates DNA repair components in cancer
- (2019) Theodoros Rampias et al. EMBO REPORTS
- Lsd1 as a therapeutic target in Gfi1-activated medulloblastoma
- (2019) Catherine Lee et al. Nature Communications
- Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes
- (2019) Tanvi Sharma et al. ACTA NEUROPATHOLOGICA
- Childhood cerebellar tumours mirror conserved fetal transcriptional programs
- (2019) Maria C. Vladoiu et al. NATURE
- Resolving medulloblastoma cellular architecture by single-cell genomics
- (2019) Volker Hovestadt et al. NATURE
- Integrated Analysis of TP53 Gene and Pathway Alterations in The Cancer Genome Atlas
- (2019) Lawrence A. Donehower et al. Cell Reports
- Diagnostic challenges in a child with early onset desmoplastic medulloblastoma and homozygous variants in MSH2 and MSH6
- (2018) Julia Taeubner et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort
- (2018) Sebastian M Waszak et al. LANCET ONCOLOGY
- Risk-adapted therapy for young children with medulloblastoma (SJYC07): therapeutic and molecular outcomes from a multicentre, phase 2 trial
- (2018) Giles W Robinson et al. LANCET ONCOLOGY
- CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2011–2015
- (2018) Quinn T Ostrom et al. NEURO-ONCOLOGY
- DNA-methylation profiling is a method of choice for molecular verification of pediatric WNT activated medulloblastomas.
- (2018) Andrey Korshunov et al. NEURO-ONCOLOGY
- Computerized assessment of cognitive impairment among children undergoing radiation therapy for medulloblastoma
- (2018) Andrew M. Heitzer et al. JOURNAL OF NEURO-ONCOLOGY
- Prognostic effect of whole chromosomal aberration signatures in standard-risk, non-WNT/non-SHH medulloblastoma: a retrospective, molecular analysis of the HIT-SIOP PNET 4 trial
- (2018) Tobias Goschzik et al. LANCET ONCOLOGY
- ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair
- (2017) Justin W.C. Leung et al. GENES & DEVELOPMENT
- Hedgehog signaling drives medulloblastoma growth via CDK6
- (2017) David R. Raleigh et al. JOURNAL OF CLINICAL INVESTIGATION
- Novel molecular subgroups for clinical classification and outcome prediction in childhood medulloblastoma: a cohort study
- (2017) Edward C Schwalbe et al. LANCET ONCOLOGY
- A UTX-MLL4-p300 Transcriptional Regulatory Network Coordinately Shapes Active Enhancer Landscapes for Eliciting Transcription
- (2017) Shu-Ping Wang et al. MOLECULAR CELL
- The whole-genome landscape of medulloblastoma subtypes
- (2017) Paul A. Northcott et al. NATURE
- OTX2 Activity at Distal Regulatory Elements Shapes the Chromatin Landscape of Group 3 Medulloblastoma
- (2017) Gaylor Boulay et al. Cancer Discovery
- Irreversible growth plate fusions in children with medulloblastoma treated with a targeted hedgehog pathway inhibitor
- (2017) Giles W. Robinson et al. Oncotarget
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- A Recurrent Mosaic Mutation in SMO , Encoding the Hedgehog Signal Transducer Smoothened, Is the Major Cause of Curry-Jones Syndrome
- (2016) Stephen R.F. Twigg et al. AMERICAN JOURNAL OF HUMAN GENETICS
- New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs
- (2016) Dominik Sturm et al. CELL
- Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma
- (2016) Michele Ceccarelli et al. CELL
- Molecular Pathways: Emergence of Protein Kinase CK2 (CSNK2) as a Potential Target to Inhibit Survival and DNA Damage Response and Repair Pathways in Cancer Cells
- (2016) A. J. Rabalski et al. CLINICAL CANCER RESEARCH
- MSI detection and its pitfalls in CMMRD syndrome in a family with a bi-allelic MLH1 mutation
- (2016) Aurélia Nguyen et al. Familial Cancer
- Active medulloblastoma enhancers reveal subgroup-specific cellular origins
- (2016) Charles Y. Lin et al. NATURE
- SMARCA4/Brg1 coordinates genetic and epigenetic networks underlying Shh-type medulloblastoma development
- (2016) X Shi et al. ONCOGENE
- The putative tumor suppressor gene EphA7 is a novel BMI-1 target
- (2016) Gaëlle Prost et al. Oncotarget
- Landscape of Phosphatidylinositol-3-Kinase Pathway Alterations Across 19 784 Diverse Solid Tumors
- (2016) Sherri Z. Millis et al. JAMA Oncology
- Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog–Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032
- (2015) Giles W. Robinson et al. JOURNAL OF CLINICAL ONCOLOGY
- Biomarker-driven stratification of disease-risk in non-metastatic medulloblastoma: Results from the multi-center HIT-SIOP-PNET4 clinical trial
- (2015) Steven C. Clifford et al. Oncotarget
- RNA interference screening identifies a novel role for PCTK1/CDK16 in medulloblastoma with c-Myc amplification
- (2015) Paulina Ćwiek et al. Oncotarget
- Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort
- (2014) Torsten Pietsch et al. ACTA NEUROPATHOLOGICA
- Late toxicity following craniospinal radiation for early-stage medulloblastoma
- (2014) Kaitlin M. Christopherson et al. ACTA ONCOLOGICA
- Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition
- (2014) Marcel Kool et al. CANCER CELL
- Germline Mutations inSUFUCause Gorlin Syndrome–Associated Childhood Medulloblastoma and Redefine the Risk Associated WithPTCH1Mutations
- (2014) Miriam J. Smith et al. JOURNAL OF CLINICAL ONCOLOGY
- Cytogenetic Prognostication Within Medulloblastoma Subgroups
- (2014) David J.H. Shih et al. JOURNAL OF CLINICAL ONCOLOGY
- Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
- (2014) Paul A. Northcott et al. NATURE
- The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes
- (2014) Robert Huether et al. Nature Communications
- PTEN Loss Mitigates the Response of Medulloblastoma to Hedgehog Pathway Inhibition
- (2013) C. Metcalfe et al. CANCER RESEARCH
- Structural Basis for Cul3 Protein Assembly with the BTB-Kelch Family of E3 Ubiquitin Ligases
- (2013) Peter Canning et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Subgroup-Specific Prognostic Implications ofTP53Mutation in Medulloblastoma
- (2013) Nataliya Zhukova et al. JOURNAL OF CLINICAL ONCOLOGY
- Simultaneous Colonic Adenocarcinoma and Medulloblastoma in a 12-Year-Old with Biallelic Deletions in PMS2
- (2013) Holly Lindsay et al. JOURNAL OF PEDIATRICS
- Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis
- (2013) Vijay Ramaswamy et al. LANCET ONCOLOGY
- Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy
- (2013) Cigall Kadoch et al. NATURE GENETICS
- Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas
- (2012) Marcel Kool et al. ACTA NEUROPATHOLOGICA
- A Mouse Model of the Most Aggressive Subgroup of Human Medulloblastoma
- (2012) Daisuke Kawauchi et al. CANCER CELL
- An Animal Model of MYC-Driven Medulloblastoma
- (2012) Yanxin Pei et al. CANCER CELL
- Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations
- (2012) Tobias Rausch et al. CELL
- MYC on the Path to Cancer
- (2012) Chi V. Dang CELL
- Outcome of Children With Metastatic Medulloblastoma Treated With Carboplatin During Craniospinal Radiotherapy: A Children's Oncology Group Phase I/II Study
- (2012) Regina I. Jakacki et al. JOURNAL OF CLINICAL ONCOLOGY
- Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations
- (2012) Trevor J. Pugh et al. NATURE
- Novel mutations target distinct subgroups of medulloblastoma
- (2012) Giles Robinson et al. NATURE
- Dissecting the genomic complexity underlying medulloblastoma
- (2012) David T. W. Jones et al. NATURE
- Subgroup-specific structural variation across 1,000 medulloblastoma genomes
- (2012) Paul A. Northcott et al. NATURE
- Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct
- (2011) Paul A. Northcott et al. ACTA NEUROPATHOLOGICA
- Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups
- (2011) David W. Ellison et al. ACTA NEUROPATHOLOGICA
- Molecular subgroups of medulloblastoma: the current consensus
- (2011) Michael D. Taylor et al. ACTA NEUROPATHOLOGICA
- OTX2 directly activates cell cycle genes and inhibits differentiation in medulloblastoma cells
- (2011) Jens Bunt et al. INTERNATIONAL JOURNAL OF CANCER
- Adult Medulloblastoma Comprises Three Major Molecular Variants
- (2011) Marc Remke et al. JOURNAL OF CLINICAL ONCOLOGY
- Joint Binding of OTX2 and MYC in Promotor Regions Is Associated with High Gene Expression in Medulloblastoma
- (2011) Jens Bunt et al. PLoS One
- Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
- (2010) Houtan Noushmehr et al. CANCER CELL
- Impact of radiation avoidance on survival and neurocognitive outcome in infant medulloblastoma
- (2010) L. Lafay-Cousin et al. Current Oncology
- Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome
- (2010) Yoon-Jae Cho et al. JOURNAL OF CLINICAL ONCOLOGY
- Medulloblastoma Comprises Four Distinct Molecular Variants
- (2010) Paul A. Northcott et al. JOURNAL OF CLINICAL ONCOLOGY
- Subtypes of medulloblastoma have distinct developmental origins
- (2010) Paul Gibson et al. NATURE
- The Genetic Landscape of the Childhood Cancer Medulloblastoma
- (2010) D. W. Parsons et al. SCIENCE
- Outcome Prediction in Pediatric Medulloblastoma Based on DNA Copy-Number Aberrations of Chromosomes 6q and 17q and theMYCandMYCNLoci
- (2009) Stefan Pfister et al. JOURNAL OF CLINICAL ONCOLOGY
- Large cell/anaplastic medulloblastoma: Outcome according to myc status, histopathological, and clinical risk factors
- (2009) Katja von Hoff et al. PEDIATRIC BLOOD & CANCER
- Two new patients with Curry-Jones syndrome with trichoblastoma and medulloblastoma suggest an etiologic role of the sonic hedgehog-patched-GLI pathway
- (2008) Dorothy K. Grange et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Acquisition of Granule Neuron Precursor Identity Is a Critical Determinant of Progenitor Cell Competence to Form Shh-Induced Medulloblastoma
- (2008) Ulrich Schüller et al. CANCER CELL
- Hyperfractionated Accelerated Radiotherapy in the Milan Strategy for Metastatic Medulloblastoma
- (2008) Lorenza Gandola et al. JOURNAL OF CLINICAL ONCOLOGY
- Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features
- (2008) Marcel Kool et al. PLoS One
- PRDM6 is enriched in vascular precursors during development and inhibits endothelial cell proliferation, survival, and differentiation
- (2007) Yaxu Wu et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now