Article
Biochemical Research Methods
Rupesh Banerjee, Barun Das Gupta, Amit Kar, Pardeep Kumar Bhardwaj, Nanaocha Sharma, Pallab Kanti Haldar, Rajib Bandyopadhyay, Pulok Kumar Mukherjee
Summary: This study evaluated the quality of pre- and post-marketed black rice samples using a validated high-performance thin layer chromatography method, and determined variations in total phenolics and total flavonoids with antioxidant potential. The results identified differences in quality among different varieties of black rice and demonstrated correlations between phenolic and flavonoid content and antioxidant potential. This study provides a useful method for the quality evaluation and nutritional authentication of black rice and its derived products.
PHYTOCHEMICAL ANALYSIS
(2023)
Article
Chemistry, Applied
Brian Quinn, Philip McCarron, Yunhe Hong, Nicholas Birse, Di Wu, Christopher T. Elliott, Ratnasekhar Ch
Summary: The COVID-19 pandemic has increased the risk of food fraud in the food industry, specifically in the case of rice, due to production gaps and changes in supply and demand. This study successfully used ICP-MS elemental profiling and elementomic modelling to identify the geographical origins of Indian, Chinese, and Vietnamese rice. The developed models exhibited good discrimination, sensitivity, and specificity.
Article
Food Science & Technology
Miso Kim, Junyoung Hong, Dongwon Lee, Sohyun Kim, Hyang Sook Chun, Yoon-Ho Cho, Byung Hee Kim, Sangdoo Ahn
Summary: This study successfully discriminated between the geographical origins of Asian red pepper powders using FT-IR spectroscopy and multivariate analysis. The establishment of canonical discriminant functions based on eight peak variables was validated through blind testing, indicating the feasibility of identifying the origins of red pepper powders.
Article
Food Science & Technology
Araceli Rivera-Perez, Roberto Romero-Gonzalez, Antonia Garrido Frenich
Summary: An untargeted metabolomics approach using UHPLC-HRMS technology was applied to study metabolic differences of black pepper from different geographical origins and processing methods. PCA and OPLSDA were utilized for sample clustering and discrimination, with 8 potential differential metabolites identified. The NMR-UHPLC-GC mid-level fused model showed excellent performance in geographical and processing discrimination.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Food Science & Technology
Emily Fanning, Graham Eyres, Russell Frew, Biniam Kebede
Summary: This paper reviews the methods to trace the geographical origin of cocoa beans and classify cocoa or chocolate based on specific quality attributes. The integration of instrumental and sensory attributes is important to establish robust geographical indications. There is a need for a more rapid and non-destructive analytical approach to modernize traditional traceability methods.
Article
Food Science & Technology
Huan Cheng, Wenyan Wu, Jin Chen, Haibo Pan, Enbo Xu, Shiguo Chen, Xingqian Ye, Jianle Chen
Summary: The study found that anthocyanin content plays a significant role in distinguishing the geographical origin of black wolfberries, making it a useful chemical marker for identification. By analyzing the chemical compositions and anthocyanin fingerprints of black wolfberries from different provinces, the study identified new individual anthocyanins and demonstrated a clear separation of geographical origins based on anthocyanin profiles.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Applied
Suel Hye Hur, Hyoyoung Kim, Yong-Kyoung Kim, Jae Min An, Ji Hye Lee, Seyeon Kim, Young-Hwa Choi, Ho Jin Kim
Summary: This study developed a method using inductively coupled plasma optical emission spectroscopy and mass spectrometry to accurately identify the origin of dry red pepper. Acid treated samples were analyzed for the contents of 60 elements, and the results showed a high ratio and prediction ratio of the model used. By selecting 26 elements with a VIP value greater than 1, the accuracy of identifying domestic and imported products was confirmed to be 98.7% based on ROC analysis. The content of rare earth elements (REEs) in imported dry red pepper was significantly higher than in domestic samples.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Chemistry, Analytical
Trung Nguyen-Quang, Minh Bui-Quang, Minh Truong-Ngoc
Summary: In this study, ICP-MS analytical method and multivariate statistical methods were used to analyze 38 soybean samples from 4 countries, determining significant differences in elemental composition among the samples and establishing accurate classification of soybeans based on their original locations. This research provides a foundation for future studies on soybean provenance using a combination of elemental composition analysis and statistical methods to identify key markers for origin discrimination.
JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY
(2021)
Article
Soil Science
Chinedu C. Obieze, Paul B. L. George, Brian Boyle, Damase P. Khasa
Summary: This study evaluated the health status of black pepper rhizosphere bacterial communities in two provinces in Vietnam and identified biomarkers and keystone species associated with plant health. Unhealthy orchards had higher electrical conductivity, clay, and nitrogen levels. The composition of bacterial communities differed between healthy and unhealthy orchards, with orchard state and physicochemical variables playing a significant role. Gemmatimonas was identified as a potential plant growth antagonist and a keystone species in unhealthy orchards. The study presents biomarkers and keystone species that can contribute to black pepper rhizosphere pathogen management.
APPLIED SOIL ECOLOGY
(2023)
Article
Chemistry, Applied
Ratnasekhar Ch, Olivier Chevallier, Philip McCarron, Terence F. McGrath, Di Wu, Le Nguyen Doan Duy, Arun P. Kapil, Mary McBride, Christopher T. Elliott
Summary: The study utilized HS-GC-MS technology to establish a model that can accurately identify rice samples from China, India, and Vietnam, with high discrimination and accuracy.
Article
Geosciences, Multidisciplinary
D. J. MacAllister, G. Krishan, M. Basharat, D. Cuba, A. M. MacDonald
Summary: The groundwater systems of northwest India and central Pakistan are heavily exploited and have experienced significant depletion. This study provides a historical context for groundwater depletion by analyzing long-term observation-well data. The results reveal the combined effects of human activity and climate on historical groundwater trends.
Article
Chemistry, Applied
Araceli Rivera-Perez, Roberto Romero-Gonzalez, Antonia Garrido Frenich
Summary: This study successfully differentiated black pepper samples based on their geographical origin and quality processing using H-1 NMR spectroscopy and chemometrics. PCA and OPLS-DA analysis resulted in high goodness-of-fit and predictive ability models, and identified major chemical markers in black pepper.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2022)
Article
Chemistry, Analytical
Shangyong Zhao, Weiran Song, Zongyu Hou, Zhe Wang
Summary: This study successfully utilized LIBS and HSI technologies combined with chemometrics to rapidly and accurately determine the plant species, geographical origin, and age of ginseng samples. The results demonstrated the effectiveness of this method for assessing the authenticity of ginseng.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2021)
Article
Spectroscopy
Wanjun Long, Qi Zhang, Si-Rui Wang, Yixin Suo, Hengye Chen, Xiuyun Bai, Xiaolong Yang, Yan-Ping Zhou, Jian Yang, Haiyan Fu
Summary: In this study, hyperspectral imaging combined with chemometrics was used to accurately classify the geographical origin of Hangbaiju. The results showed that the bagging classification tree-radial basis function based on optimal wavelengths achieved superior classification performances compared to traditional methods.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Biochemistry & Molecular Biology
Alvaro Cruz-Carrion, Ma. Josefina Ruiz de Azua, Francisca Isabel Bravo, Gerard Aragones, Begona Muguerza, Manuel Suarez, Anna Arola-Arnal
Summary: Tomatoes are an important source of health-promoting antioxidants, with seasonal consumption showing potential to improve or maintain antioxidant biomarkers and reduce oxidative stress. The protective effect of tomatoes against oxidative stress depends on their geographical origin, suggesting that in-season consumption may have health benefits by preventing oxidative stress.
Review
Integrative & Complementary Medicine
Rizwan Ahmad, Hawra Adnan Alsadah, Muhammad Riaz, Lina Hussain AlLehaibi, Reem Ahmed Alraya, Ahmed Aljamea, Saira Zahoor
Summary: Gingko biloba (GB) has interactions with drugs, herbs, and nutraceuticals, affecting drug metabolism and platelet function, leading to potential adverse effects. Monitoring and seeking advice from healthcare professionals are recommended for GB use.
BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMATICAS
(2021)
Article
Biochemistry & Molecular Biology
Ashraf N. Abdalla, Miriana Di Stefano, Giulio Poli, Tiziano Tuccinardi, Ammar Bader, Antonio Vassallo, Mohamed E. Abdallah, Mahmoud Zaki El-Readi, Bassem Refaat, Alanood S. Algarni, Rizwan Ahmad, Hamad M. Alkahtani, Alaa A. -M. Abdel-Aziz, Adel S. El-Azab, Aljawharah Alqathama
Summary: The present study investigated the cytotoxic, chemosensitizing, and apoptotic effects of a compound called HAA(2021) on breast cancer cells and breast cancer cells resistant to doxorubicin. The study also explored the binding mode of HAA(2021) with P-glycoprotein (P-gp) and heat shock protein 90 (Hsp90) and its contribution to chemosensitization. The results showed that when combined with doxorubicin, HAA(2021) synergistically inhibited proliferation and induced significant apoptosis in breast cancer cells. It also increased the chemosensitization of resistant cells to doxorubicin. Furthermore, molecular modeling studies revealed that HAA(2021) binds to P-gp and Hsp90, leading to inhibition of the MDR efflux pump and increased chemosensitization.
Article
Chemistry, Multidisciplinary
Mohammed Aldholmi, Rizwan Ahmad, Daniel Carretero-Molina, Ignacio Perez-Victoria, Jesus Martin, Fernando Reyes, Olga Genilloud, Lea Gourbeyre, Thierry Gefflaut, Hanne Carlsson, Alexei Maklakov, Ellis O'Neill, Robert A. Field, Barrie Wilkinson, Maria O'Connell, A. Ganesan
Summary: The study discovered that euglenatides from Euglena gracilis can inhibit pathogenic fungi and cancer cells, and bear resemblance to nemamides in Caenorhabditis elegans. Molecular network analysis also revealed the presence of multiple euglenatide-like metabolites in Euglena species.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Review
Integrative & Complementary Medicine
Muhammad Riaz, Majid Khan, Rizwan Ahmad, Lina Hussain AlLehaibi, Najmur Rahman, Dou Deqiang
Summary: This study investigates the potential effects of Nigella sativa L. (NS) on coronavirus and finds that it can boost the immune system and alleviate respiratory symptoms. NS plays a significant role in treating various diseases. The research shows that NS has a notable antiviral effect against a specific coronavirus strain.
BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMATICAS
(2022)
Article
Chemistry, Applied
Rizwan Ahmad, Heba Shaaban, Sahar Y. Issa, Anwar Alsaad, Majd Alghamdi, Njoud Hamid, Rand Osama, Sara Algarni, Ahmed Mostafa, Abdulmalik M. Alqarni, Mohammed Aldholmi, Muhammad Riaz
Summary: The study found that various elements were widely present in medicinal plant samples from the Kingdom of Saudi Arabia, with some elements exceeding the maximum limits. Statistical analysis validated the data and provided baseline information for selecting safe medicinal plants.
FOOD ADDITIVES & CONTAMINANTS PART B-SURVEILLANCE
(2022)
Article
Food Science & Technology
Rizwan Ahmad, Mohammed Aldholmi, Ahmed Mostafa, Aljawharah Alqathama, Alaa Aldarwish, Asma Abuhassan, Leena Alateeq, Salem Bubshait, Muath Aljaber, Saeed Aldossary
Summary: This study developed a novel and green ASE technique combined with UPLC-MS/MS for comprehensive characterization of MG in mango fruit. The results showed that the highest yield and MG amount were obtained through ASE with H2O at 80 degrees C for the mesocarp fruit part. The intra-variation of MG was found to be mesocarp > endocarp > epicarp > seed. Statistical models revealed significant correlations between origin, solvent, temperature, and MG amount, while there was no significant correlation between origin and extract yield. This study provides valuable insights into the inter- and intra-variation of MG in different parts of mango fruit.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Review
Plant Sciences
Aljawharah A. Alqathama, Rizwan Ahmad, Ruba B. Alsaedi, Raghad A. Alghamdi, Ekram H. Abkar, Rola H. Alrehaly, Ashraf N. Abdalla
Summary: This review focuses on natural products and their derivatives that have been evaluated for antiviral, anti-inflammatory, and immunomodulatory properties. Various classes of compounds, including flavonoids, polyphenols, peptides, and tannins, have shown inhibitory properties against viral and host proteins. Many of these compounds are in different phases of clinical trials.
PHARMACEUTICAL BIOLOGY
(2022)
Article
Pharmacology & Pharmacy
Heba Shaaban, Sahar Y. Issa, Rizwan Ahmad, Ahmed Mostafa, Sara Refai, Nooran Alkharraa, Batool T. Albaqshi, Dania Hussien, Abdulmalik M. Alqarni
Summary: This study investigated the metal contamination in popular lip cosmetic products sold in Saudi Arabian markets and assessed the associated human health risks. The concentrations of most investigated metals were below the safe limits, except for Cd, Pb, and Hg. Cd was identified as the primary metal contaminant, contributing to the majority of the carcinogenic health risk. Overall, the use of these lip products was found to have no significant health risks.
SAUDI PHARMACEUTICAL JOURNAL
(2022)
Article
Plant Sciences
Mohd Amir, Ameeduzzafar Zafar, Rizwan Ahmad, Wasim Ahmad, Mohammad Sarafroz, Mohammad Khalid, Mohammed M. Ghoneim, Sultan Alshehri, Shadma Wahab, Sayeed Ahmad, Mohd Mujeeb
Summary: The increase in the use of herbal medicines has led to more stringent regulations for quality variation and standardization. This study aimed to standardize Prunus domestica Linn. using various evaluation techniques, advanced instrumental analysis, and biological and toxicological techniques. The results showed that the fruit met quality requirements and did not contain harmful substances beyond the permissible limits.
Article
Plant Sciences
Rizwan Ahmad, Aljawharah Alqathama, Mohammed Aldholmi, Muhammad Riaz, Ashraf N. Abdalla, Ahmed Mostafa, Hamdi M. Al-Said, Abdulmalik M. Alqarni, Riaz Ullah, Sami S. Asgher, Mohd Amir, Heba Shaaban, Wasim Ahmad
Summary: This study evaluates the quality variation of twenty-seven capsicum fruit samples in terms of their volatile oil composition and biological activities. The results indicated that the C16 sample exhibited the best activity and showed significant potential for further study.
Article
Chemistry, Analytical
Ahmed Mostafa, Heba Shaaban, Abdulmalik M. Alqarni, Meshal Alghamdi, Semat Alsultan, Jenan Saleh Al-Saeed, Sahar Alsaba, Amal AlMoslem, Yasir Alshehry, Rizwan Ahmad
Summary: This study explores the use of natural deep eutectic solvents (NDESs) for the extraction and trace analysis of sulfonamides. The results show that using a thymol/acetic acid mixture as the extracting solvent yields the best extraction recovery. The proposed method is found to be superior to other methods based on ecological assessments and other metrics. Overall, this method can serve as a valid eco-friendly alternative for the routine analysis of sulfonamides in different water samples.
MICROCHEMICAL JOURNAL
(2022)
Review
Chemistry, Medicinal
Ashraf Ullah Khan, Adnan Khan, Bushra Shal, Salman Khan, Majid Khan, Rizwan Ahmad, Muhammad Riaz
Summary: Cancer is a major global health issue, with increasing cases each year. The development of cancer is influenced by various factors such as radiation, lifestyle, smoking, environment, and genetics. The cell cycle, regulated by molecular signaling proteins, is disrupted when these proteins are altered, affecting cellular growth and proliferation. Natural products, including phytosterols, have shown promising anti-cancer activities by modulating molecular signaling pathways involved in the tumor microenvironment. Further research is required to establish the clinical efficacy and safety of phytosterols.
PHYTOTHERAPY RESEARCH
(2023)
Article
Acoustics
Rizwan Ahmad, Mohammed Aldholmi, Aljawharah Alqathama, Ebtihal Althomali, Fatema Aljishi, Ahmed Mostafa, Abdulmalik M. Alqarni, Heba Shaaban
Summary: This is the first report to evaluate the effect of natural antioxidants, pH, and green solvents on the yield and stability of catechins during the extraction process from green tea leaves. The results showed that using green solvents augmented with natural antioxidants and at a low pH of 2 resulted in the highest yield and better stability of catechins.
ULTRASONICS SONOCHEMISTRY
(2023)
Article
Acoustics
Rizwan Ahmad, Aljawharah Alqathama, Mohammed Aldholmi, Muhammad Riaz, Sayed M. Eldin, Mohammad Mahtab Alam, Shaimaa A. M. Abdelmohsen
Summary: This study reports the simultaneous determination of flavonoids in fenugreek seeds samples using a green UHPLC-DAD analysis. Different polarity solvents were used for the ultrasound-assisted extraction of flavonoids. The results showed significant variations in the flavonoid content among different origins of fenugreek seeds.
ULTRASONICS SONOCHEMISTRY
(2023)
Article
Chemistry, Medicinal
Rizwan Ahmad, Aljawharah Alqathama, Mohammed Aldholmi, Muhammad Riaz, Ashraf N. Abdalla, Fatema Aljishi, Ebtihal Althomali, Mohd Amir, Omeima Abdullah, Muntathir Ali Alamer, Deema Alaswad, Wala Alsulais, Ahad Alsulays
Summary: This study comprehensively screened the biological activities of all four parts of mango fruit from twelve different origins and found that the seed part exhibited significant biological activities. Further metabolomic and in vivo studies are essential to effectively utilize the seed part for the treatment of various diseases.