Cytosolic domain of SIDT2 carries an arginine-rich motif that binds to RNA/DNA and is important for the direct transport of nucleic acids into lysosomes

Lysosomal targeting of SIDT2 via multiple YxxΦ motifs is required for SIDT2 function in the process of RNautophagy

(2017) Viorica Raluca Contu et al.   JOURNAL OF CELL SCIENCE

SIDT2 mediates gymnosis, the uptake of naked single-stranded oligonucleotides into living cells

(2017) Masayuki Takahashi et al.   RNA Biology

Lysosomal membrane protein SIDT2 mediates the direct uptake of DNA by lysosomes

(2016) Shu Aizawa et al.   Autophagy

Lysosomal putative RNA transporter SIDT2 mediates direct uptake of RNA by lysosomes

(2016) Shu Aizawa et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

An RNautophagy/DNautophagy receptor, LAMP2C, possesses an arginine-rich motif that mediates RNA/DNA-binding

(2015) Yuuki Fujiwara et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Systemic RNA Interference Deficiency-1 (SID-1) Extracellular Domain Selectively Binds Long Double-stranded RNA and Is Required for RNA Transport by SID-1

(2015) Weiqiang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular basis of ligand recognition and transport by glucose transporters

(2015) Dong Deng et al.   NATURE

RNautophagy/DNautophagy possesses selectivity for RNA/DNA substrates

(2015) Katsunori Hase et al.   NUCLEIC ACIDS RESEARCH

Structural basis for substrate specificity of an amino acid ABC transporter

(2015) Jie Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polyglutamine (PolyQ) Diseases: Genetics to Treatments

(2014) Hueng-Chuen Fan et al.   CELL TRANSPLANTATION

Discovery of a novel type of autophagy targeting RNA

(2013) Yuuki Fujiwara et al.   Autophagy

Direct uptake and degradation of DNA by lysosomes

(2013) Yuuki Fujiwara et al.   Autophagy

An Extended Proteome Map of the Lysosomal Membrane Reveals Novel Potential Transporters

(2013) Agnès Chapel et al.   MOLECULAR & CELLULAR PROTEOMICS

SID-1 is a dsRNA-selective dsRNA-gated channel

(2011) J. D. Shih et al.   RNA

SID1 transmembrane family, member 2 (Sidt2): A novel lysosomal membrane protein

(2010) Gao Jialin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS