Article
Chemistry, Multidisciplinary
Jasmine Jan, Juan Zhu, Jonathan Ting, Ana C. Arias
Summary: This study utilizes surface-energy-patterning to enable simultaneous blade coating of organic photodiode and organic light-emitting diode films, achieving dual functionality on a single flexible substrate. Optimized performance of each device is achieved by optimizing active layer thicknesses. This technique allows for the printing of two functionally distinct devices in a single step without compromising their performance.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Qiuyu Yang, Xiuli Sun, Yichao Sun, Xiaofang Shen, Yuehong Pang
Summary: An electrochemical sensor, Bi-BDC-NH2@NMCS, was developed by combining an amino-functionalized bismuth metal-organic framework (Bi-BDC-NH2) with nitrogen-doped mesoporous carbon nanosphere (NMCS), enabling simultaneous determination of Pb(II) and Cd(II). The Bi-BDC-NH2@NMCS electrode exhibited improved charge transfer, stability, and conductivity compared to the traditional bismuth film electrode. The method demonstrated excellent stripping performance with low detection limits and a wide linear range, and was successfully applied to the detection of Pb(II) and Cd(II) in liver, fish, and shrimp samples with high recoveries.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Yang Wang, Yang Hu, Junfeng Guo, Zongrui Wang, Yang Li, Fengxiang Qie, Chunfeng Shi, Lei Zhang, Yonggang Zhen
Summary: In this study, a series of difunctionalized acenaphthylene imides (ANIs) with varied optoelectronic properties were successfully synthesized through copper-promoted domino cyanation/Ullmann coupling. The optical and electrical characteristics of the ANI compounds could be rationally tailored by altering the functional units, leading to the achievement of p, n or ambipolar semiconducting properties. This research opens up possibilities for the development of organic semiconducting materials based on ANIs without aromatic extension, showing promising applications in organic electronics.
SCIENCE CHINA-CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Youxing Liu, Yanan Wei, Minghui Liu, Yichao Bai, Guocai Liu, Xinyu Wang, Shengcong Shang, Wenqiang Gao, Changsheng Du, Jianyi Chen, Yunqi Liu
Summary: Researchers have fabricated a novel 2D MOF film and successfully applied it in simulating human brain synapses, demonstrating excellent synaptic plasticity and stability. This paves the way for potential applications in artificial intelligence.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Nanoscience & Nanotechnology
Tongtong Guo, Yuanhang Xiang, Hao Lu, Minmin Huang, Fengfei Liu, Min Fang, Jia Liu, Yujin Tang, Xinchun Li, Fan Yang
Summary: In this study, a DNA framework-reversed signal-gain strategy was developed to improve the signal-to-noise ratio in charge-based electrochemical DNA sensors for ultrasensitive and highly specific electrical detection of microRNAs (miRNAs) in blood. The DNA framework-based electrochemical sensor exhibited high sensitivity and specificity, allowing for the detection of tumor-associated miRNAs in complex matrices and the differentiation of tumor patients from normal individuals.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Multidisciplinary
Sophia S. Y. Chan, Denise Lee, Maria Prisca Meivita, Lunna Li, Yaw Sing Tan, Natasa Bajalovic, Desmond K. Loke
Summary: This study demonstrates the use of carbon nanotubes to alter the bioelectrical signatures of cells and develop a sensor based on alternating current pulses and light irradiation to differentiate between healthy and cancer cells. Molecular dynamics simulations reveal the interaction between carbon nanotubes and cancer cell membranes, resulting in a change in lipid bilayer structure and enhancing current. This cancer cell-specific method offers a promising route for early diagnosis and monitoring of cancer.
Article
Chemistry, Multidisciplinary
Xu Yan, Dandan Su, Hongxia Li, Xu Zhao, Xiaomin Liu, Fangmeng Liu, Peng Sun, Geyu Lu
Summary: Hierarchically porous enzyme@peptide-directed metal-organic frameworks (enzyme@MOFs-P) nanoarchitectures were constructed by implemented site-selective epitaxial growth to create mesopore and defect structures. The enzyme@MOFs-P-based plasmonic immunosensor showed improved sensitivity for the detection of imidacloprid pesticide compared to a typical immunoassay, achieving quantitative detection with a half maximal inhibitory concentration of 0.02 ng mL(-1). This work provides valuable insights into engineering size-tunable nanostructures and the structure-activity relationship of MOFs, guiding the construction of plasmonic biosensors for on-site application.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Jihyung Lee, Byeongsu Kim, Changjo Kim, Min-Ho Lee, Irem Kozakci, Sungjun Cho, Beomil Kim, Sang Yeon Lee, Junho Kim, Jihun Oh, Jung-Yong Lee
Summary: To unlock the potential of CQD/organic hybrid devices, we adjusted the interface properties between the ETL and CQD layers by incorporating an EIL. The EIL with a cascading band offset effectively suppressed potential barriers and local charge accumulation at the interfaces, leading to reduced recombination. An optimal EIL expanded the depletion region and facilitated charge extraction, preventing the formation of shallow traps. Devices with an EIL achieved a maximum power conversion efficiency of 14.01% and maintained over 80% of initial performance after 300 hours of continuous operation.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Bo Li, Xinlei Yu, Junjun Wang, Hui Tang, Xianshun Sun, Longjiu Cheng, Hongping Zhou, Yupeng Tian, Dandan Li
Summary: This study demonstrates the importance of engineering high-order multiphoton excited fluorescent materials in the fields of sensing, 3D optical data storage, and bioimaging. By incorporating octupolar modules within a metal-organic framework, new possibilities for the design of attractive H-MPEF materials are created. The study also shows that these materials have the potential for cancer cell-specific targeting oncotherapy using tissue-penetrating NIR-II light.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Analytical
Mei-Jie Wei, Xin-Yang Lu, Jing Li, Fen-Ying Kong, Jie Zhou, Zhong-Xia Wang, Wei Wang
Summary: A highly conductive covalent organic framework coupled with nitrogen doped carbon nanotubes was developed for the simultaneous quantitation of xanthine and hypoxanthine. The nanocomposites exhibited low detection limits, wide linear ranges, and excellent selectivity, repeatability, and stability. The approach was successfully applied to quantify xanthine and hypoxanthine in human urine and fish meat.
MICROCHEMICAL JOURNAL
(2023)
Article
Spectroscopy
Zahra Khoshbin, Javad Zamanian, Negin Davoodian, Noor Mohammad Danesh, Mohammad Ramezani, Mona Alibolandi, Khalil Abnous, Seyed Mohammad Taghdisi
Summary: The designed aptasensor in this study allows for ultra-sensitive detection of ethanolamine at low cost, demonstrating high sensitivity and simplicity, suitable for applications in food safety control, human diagnostics, and environmental monitoring.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Multidisciplinary
Sumon Hati, Xuehui Yang, Prashant Gupta, Barry B. Muhoberac, Jingzhi Pu, Jing Zhang, Rajesh Sardar
Summary: This study reports the programmable manipulation of inorganic-organic interfacial electronic properties of ligand-functionalized plasmonic nanoparticles (NPs), which is crucial for their applications such as catalysis, photovoltaics, and biosensing. By functionalizing gold triangular nanoprisms (Au TNPs) with thiocinnamate ligands of varying surface dipole moments, the localized surface plasmon resonance (LSPR) properties of the Au TNPs in solid state can be reversibly tuned with a significant peak broadening. The shape of the NPs has a significant impact on the plasmonic response and work function modulation.
Article
Chemistry, Physical
Xin Zhao, Muhammad Sajjad, Yaqian Zheng, Miaomiao Zhao, Zijie Li, Zhengyi Wu, Kun Kang, Li Qiu
Summary: This study introduces ordered nanoporous C-60 prepared using covalent organic frameworks (COFs) as a template for high-performance supercapacitors. Through optimization, the device exhibits high energy density and excellent electrochemical behavior, showing promising prospects for future energy storage.
Article
Biophysics
Xiaojuan Liu, Yuecan Zhao, Feng Li
Summary: This study presents an immobilization-free PEC biosensor for ultrasensitive determination of CEA, utilizing DNA-functionalized MOFs and T7 exonuclease-assisted recycling amplification. The biosensor shows a low detection limit, wide linear range, high selectivity for CEA detection, and great potential for application in bioanalysis and early disease diagnosis.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Multidisciplinary
Samraj Mollick, Sujeet Rai, Louis Frentzel-Beyme, Vishal Kachwal, Lorenzo Dona, Dagmar Schuermann, Bartolomeo Civalleri, Sebastian Henke, Jin-Chong Tan
Summary: A water-resistant metal-organic framework (MOF)-based composite has been developed for selective detection of acetone vapor in the diabetic range, achieving rapid detection through fluorescence approach and the ability of reuse.
Article
Biophysics
Mengyuan Chen, Zhenqiang Ning, Xue Ge, Erli Yang, Qian Sun, Fei Yin, Mingming Zhang, Yuanjian Zhang, Yanfei Shen
Summary: This study presents a simple and effective strategy to prepare gold nanoclusters with high photoluminescence (PL) through ligands engineering. The assembled arginine ligands on the MTU-protected Au nanoclusters led to significantly enhanced PL emission, which displayed rapid and reversible responses to various types of ions. These findings provide new insights into regulating the PL emission of Au nanoclusters and advance their potential applications in information encryption and bioassays.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Materials Science, Multidisciplinary
Yuhua Hou, Yanfeng Fang, Zhixin Zhou, Qing Hong, Wang Li, Hong Yang, Kaiqing Wu, Yuan Xu, Xuwen Cao, Dan Han, Songqin Liu, Yanfei Shen, Yuanjian Zhang
Summary: This study reports a highly stable carbon nitride film with an unusually enhanced electrochemically generated chemiluminescence (ECL) efficiency, which is 2256 times higher than that of the reference Ru(bpy)(3)Cl-2/K2S2O8. Double crystallization plays a crucial role in the preparation. The improved ECL efficiency is attributed to the suppression of futile co-reagent reduction by little pinholes, the maintenance of more orbit-delocalized heptazine subunits to improve ECL kinetics, and the high transparency of the film to avoid self-absorption. Furthermore, an ultrasensitive visual DNA biosensor by the naked eye is successfully developed with a linear detection range of 100 pm to 1 μm and a limit of detection of 27 pm (S/N = 3).
ADVANCED OPTICAL MATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Ran Chen, Songqin Liu, Yuanjian Zhang
Summary: The development of low-cost and efficient catalytic materials is crucial for meeting energy demands and pursuing sustainable energy. Traditional electrochemical measurements lack the ability to characterize nanoscale surface features, but nanoelectrode-based studies offer a new approach. This mini-review summarizes recent progress in nanoelectrode-based studies on various nanostructured catalytic materials.
MATERIALS HORIZONS
(2023)
Article
Chemistry, Analytical
Yanfeng Fang, Zhixin Zhou, Yuhua Hou, Chenchen Wang, Xuwen Cao, Songqin Liu, Yanfei Shen, Yuanjian Zhang
Summary: We synthesized highly efficient polymeric carbon nitride (CN) films with fine-tuned electrochemiluminescence (ECL) emission from blue to green. The naked eye observable emission was significantly enhanced, and the cathodic ECL efficiency was greatly improved compared to the reference. The mechanism studies revealed crucial factors for the high ECL efficiency of CN. Based on the high ECL efficiency and different colors of ECL emission, a multiplexed ECL biosensor was constructed to detect miRNA-21 and miRNA-141 simultaneously with low detection limits.
ANALYTICAL CHEMISTRY
(2023)
Review
Chemistry, Multidisciplinary
Yuan Xu, Zhixin Zhou, Nankai Deng, Kangchun Fu, Caixia Zhu, Qing Hong, Yanfei Shen, Songqin Liu, Yuanjian Zhang
Summary: Nanozymes have emerged as cost-effective alternatives to natural enzymes and have gained increasing interest. To fully exploit their potential, rational structural engineering and explicit catalytic mechanisms at the molecular scale are required. Impressive progress has been made in mimicking the characteristics of natural enzymes, including the construction of metal active sites, binding pockets, scaffolds, and delicate allosteric regulation. This review introduces the state-of-the-art synthesis strategies and summarizes the general overview of the nanozyme mechanism, with a focus on adsorbed intermediates and descriptors that predict nanozyme activity. The emerging activity assessment methodology that illustrates the relationship between electrochemical oxygen reduction and enzymatic oxygen reduction is discussed, along with future opportunities and challenges to encourage further research in the field of nanozymes.
SCIENCE CHINA-CHEMISTRY
(2023)
Article
Chemistry, Analytical
Kaiqing Wu, Jingjing Ji, Hong Yang, Zhixin Zhou, Ran Chen, Sicheng Liang, Wang Li, Yanfei Shen, Songqin Liu, Yuanjian Zhang
Summary: A biosensor with a self-checking function for sensitive telomerase activity detection was constructed by integrating the ability of fluorescence detection and photodegradation by carbon nitride nanosheets (CNNS). The biosensor not only showed highly sensitive detection of telomerase activity, but also had an internal self-checking function by photodegradation of the dye acriflavine (AF) via continuous excitation and measurement of recovered fluorescence. This study provides a novel approach using CNNS-based electronic donor-acceptor interfaces for future clinical diagnosis with high sensitivity and reliability.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Multidisciplinary Sciences
Qing Hong, Hong Yang, Yanfeng Fang, Wang Li, Caixia Zhu, Zhuang Wang, Sicheng Liang, Xuwen Cao, Zhixin Zhou, Yanfei Shen, Songqin Liu, Yuanjian Zhang
Summary: This study reports an adaptable graphitic C6N6-based copper single-atom catalyst, capable of driving basic oxidation reactions of peroxidase substrates through a copper-oxo pathway and performing a second gain reaction triggered by light via a free hydroxyl radical pathway. The reactive oxygen-related intermediates of the same oxidation reaction enable consistent reaction conditions. The unique topological structure of CuSAC6N6 promotes intramolecular charge separation and migration, inhibiting negative interferences. The catalyst exhibits superior activity and gain compared to controls and is further applied to a glucose biosensor.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Analytical
Wang Li, Mingming Zhang, Dan Han, Hong Yang, Qing Hong, Yanfeng Fang, Zhixin Zhou, Yanfei Shen, Songqin Liu, Chaofeng Huang, Haibin Zhu, Yuanjian Zhang
Summary: Photoelectrochemical (PEC) sensing allows fast, accurate, and highly sensitive detection of biologically important chemicals. However, achieving high selectivity without external biological elements remains a challenge due to the poor selectivity of PEC reactions. This study presents a strategy to address this issue by regulating charge-transfer pathways using polymeric carbon nitride (pCN)-based heterojunction photoelectrodes. By controlling the redox reactions at different semiconductor/electrolyte interfaces, each analyte showed a unique combination of photocurrent-change polarity, leading to the development of a highly selective PEC sensor for ascorbic acid in serum against common interferences.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Caixia Zhu, Hong Yang, Xuwen Cao, Qing Hong, Yuan Xu, Kaiyuan Wang, Yanfei Shen, Songqin Liu, Yuanjian Zhang
Summary: This study demonstrates a direct two-electron oxidation pathway of TMB using SDS-based micelles, which overcomes the instability issue of TMB and enables reliable glucose measurement without the need for strong acid termination.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Qian Sun, Zhenqiang Ning, Erli Yang, Fei Yin, Guoqiu Wu, Yuanjian Zhang, Yanfei Shen
Summary: A facile and scalable approach for preparing self-assembled copper nanoclusters (CuNCsAssy) with high electrochemiluminescence (ECL) efficiency and stability was proposed. The self-assembly strategy promoted the electrochemical excitation and radiative transition, leading to significant enhancement of ECL. This work provides a simple and effective method to improve the ECL performance of metal nanoclusters for bioassays and clinical diagnosis.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Caixia Zhu, Zhixin Zhou, Xuejiao J. Gao, Yanhong Tao, Xuwen Cao, Yuan Xu, Yanfei Shen, Songqin Liu, Yuanjian Zhang
Summary: This article reports a nanozyme-based chemical reaction network (CRN) with feedback and feedforward functions, which can generate multiple responses to a single H2O2 stimulus. By confining this nanozymatic network to a microfluidic chip, it exhibits remarkable selectivity and linearity in perceiving H2O2 stimulus and provides an instructive platform for studying primordial life-like processes.
Article
Chemistry, Multidisciplinary
Ying Li, Yujie Chen, Kaiyuan Wang, Yufeng Zhou, Wei Wei, Yuanjian Zhang, Songqin Liu
Summary: Significant progress has been made in improving the activity of nanozymes, but there are still challenges in modulating their catalytic functions. In this study, a nanozyme (CZIF/Au) was synthesized by depositing Au nanoparticles on a CZIF. CZIF/Au displayed enhanced peroxidase-like activity under 655 nm laser irradiation and improved catalase-like activity under 808 nm laser irradiation. The different catalytic mechanisms were explained by the electron transitions triggered by the two lasers. The insights gained from this study provide a strategy for regulating the properties of nanozymes and offer prospects for their versatile use in the future.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Physical
Xiaofei Gu, Tianyi Huang, Yixin Hong, Yafeng Wu, Zhi Wang, Yuanjian Zhang, Songqin Liu, Jianyu Han
Summary: Inspired by natural photosynthesis, researchers have developed various artificial bio-coupled photocatalytic systems with promising results. However, the efficiency of these systems is hindered by the slow electron transfer kinetics. In this study, a semiartificial photosynthesis system was established using a solid electron conveyor to facilitate rapid electron transfer from the photosensitizer to the enzyme. The conformational changes induced by the framework-enzyme interaction improved the catalytic CO2 reduction rate by 190-fold compared to the traditional coenzyme system.
JOURNAL OF MATERIALS CHEMISTRY A
(2023)
Article
Chemistry, Multidisciplinary
Xiaoxiao Peng, Jin Ma, Zhixin Zhou, Hong Yang, Jingjing Chen, Ran Chen, Kaiqing Wu, Guangcheng Xi, Songqin Liu, Yanfei Shen, Yuanjian Zhang
Summary: In this study, the dissolution of polymeric carbon nitride (pCN) in polyphosphoric acid (PPA) and its fluid-phase assembly with carbon nanotubes (CNTs) into a flexible free-standing membrane were reported for the first time. The pCN/CNTs molecular composite membrane exhibited superior mechanical properties, cycling performance, and outstanding bactericidal and wound healing effects through photogenerated oxygen radicals. This opens up new possibilities for biomedical applications of pCN in molecular composite membranes beyond traditional solar fuel applications in powders.
