Molecular insights of nanozymes from design to catalytic mechanism

A Library of ROS‐Catalytic Metalloenzyme‐Mimics with Atomic Metal Centers

(2022) Sujiao Cao et al.   ADVANCED MATERIALS

Data-informed discovery of hydrolytic nanozymes

(2022) Sirong Li et al.   Nature Communications

Bridging Oxidase Catalysis and Oxygen Reduction Electrocatalysis by Model Single-Atom Catalysts

(2022) Xiangyu Lu et al.   National Science Review

Prediction and Design of Nanozymes using Explainable Machine Learning

(2022) Yonghua Wei et al.   ADVANCED MATERIALS

Single-Stranded DNA-Encoded Gold Nanoparticle Clusters as Programmable Enzyme Equivalents

(2022) Xiaoliang Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Surface Science of Nanozymes and Defining a Nanozyme Unit

(2022) Mohamad Zandieh et al.   LANGMUIR

Kinetically restrained oxygen reduction to hydrogen peroxide with nearly 100% selectivity

(2022) Jinxing Chen et al.   Nature Communications

纳米酶：新一代人工酶

(2022) Lizeng Gao et al.   Scientia Sinica Chimica

Photothermal‐Amplified Single Atom Nanozyme for Biofouling Control in Seawater

(2022) Wei Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Edge‐site Engineering of Defective Fe‐N 4 nanozymes with Boosted Catalase‐like Performance for Retinal Vasculopathies

(2022) Ruofei Zhang et al.   ADVANCED MATERIALS

A Dopamine-Enabled Universal Assay for Catalase and Catalase-Like Nanozymes

(2022) Anqi Lin et al.   ANALYTICAL CHEMISTRY

Degradable ZnS-Supported Bioorthogonal Nanozymes with Enhanced Catalytic Activity for Intracellular Activation of Therapeutics

(2022) Xianzhi Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Insights on catalytic mechanism of CeO2 as multiple nanozymes

(2022) Yuanyuan Ma et al.   Nano Research

Catalase‐Like Nanozymes: Classification, Catalytic Mechanisms, and Their Applications

(2022) Deting Xu et al.   Small

Single-atom nanozymes catalytically surpassing naturally occurring enzymes as sustained stitching for brain trauma

(2022) Shaofang Zhang et al.   Nature Communications

Ingenious Multifunctional MnO2 Quantum Dot Nanozymes with Superior Catechol Oxidase-like Activity for Highly Selective Sensing of Redox-Active Dopamine Based on an Interfacial Passivation Strategy

(2022) Wenting Zou et al.   ACS Sustainable Chemistry & Engineering

Engineering of coordination environment in bioinspired laccase-mimicking catalysts for monitoring of pesticide poisoning

(2022) Xu Yan et al.   CHEMICAL ENGINEERING JOURNAL

Machine Learning Guided Discovery of Superoxide Dismutase Nanozymes for Androgenetic Alopecia

(2022) Chaohui Zhang et al.   NANO LETTERS

Surface‐Mediated Production of Complexed •OH Radicals and FeO Species as a Mechanism for Iron Oxide Peroxidase‐Like Nanozymes

(2022) Kaiwei Wan et al.   Small

Depletable peroxidase-like activity of Fe3O4 nanozymes accompanied with separate migration of electrons and iron ions

(2022) Haijiao Dong et al.   Nature Communications

A Manganese‐Based Metal–Organic Framework as a Cold‐Adapted Nanozyme

(2022) Yao Chen et al.   ADVANCED MATERIALS

Carbon-based nanozymes: Design, catalytic mechanism, and bioapplication

(2022) Yun Sun et al.   COORDINATION CHEMISTRY REVIEWS

Surface-bound reactive oxygen species generating nanozymes for selective antibacterial action

(2021) Feng Gao et al.   Nature Communications

Catalytic activity tunable ceria nanoparticles prevent chemotherapy-induced acute kidney injury without interference with chemotherapeutics

(2021) Qinjie Weng et al.   Nature Communications

Enzymatic Cascade Reactions Mediated by Highly Efficient Biomimetic Quasi Metal–Organic Frameworks

(2021) Huan Xia et al.   ACS Applied Materials & Interfaces

In vivo activation of pH-responsive oxidase-like graphitic nanozymes for selective killing of Helicobacter pylori

(2021) Lufeng Zhang et al.   Nature Communications

Selective Hydrolysis of Aryl Esters under Acidic and Neutral Conditions by a Synthetic Aspartic Protease Mimic

(2021) Ishani Bose et al.   ACS Catalysis

Bionic design of cytochrome c oxidase-like single-atom nanozymes for oxygen reduction reaction in enzymatic biofuel cells

(2021) He Zhang et al.   Nano Energy

Matching the kinetics of natural enzymes with a single-atom iron nanozyme

(2021) Shufang Ji et al.   Nature Catalysis

Aptamer-Modified Cu2+-Functionalized C-Dots: Versatile Means to Improve Nanozyme Activities-“Aptananozymes”

(2021) Yu Ouyang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Platinum–Copper Bimetallic Colloid Nanoparticle Cluster Nanozymes with Multiple Enzyme-like Activities for Scavenging Reactive Oxygen Species

(2021) Yan Liu et al.   LANGMUIR

Glucose-oxidase like catalytic mechanism of noble metal nanozymes

(2021) Jinxing Chen et al.   Nature Communications

Nanozyme-Enabled Analytical Chemistry

(2021) Sirong Li et al.   ANALYTICAL CHEMISTRY

Defect engineering in nanozymes

(2021) Yu Wu et al.   Materials Today

TiO2 supported single Ag atoms nanozyme for elimination of SARS-CoV2

(2021) Daji Wang et al.   Nano Today

Nanozymes: A clear definition with fuzzy edges

(2021) Hui Wei et al.   Nano Today

Accelerated discovery of superoxide-dismutase nanozymes via high-throughput computational screening

(2021) Zhenzhen Wang et al.   Nature Communications

Specific “Unlocking” Nanozyme-based Butterfly Effect for Breaking the Evolutionary Fitness of Chaotic Tumor

(2020) Wenyao Zhen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanozymes: created by learning from nature

(2020) Ruofei Zhang et al.   Science China-Life Sciences

Self-assembled single-atom nanozyme for enhanced photodynamic therapy treatment of tumor

(2020) Dongdong Wang et al.   Nature Communications

White Peroxidase‐Mimicking Nanozymes: Colorimetric Pesticide Assay without Interferences of O 2 and Color

(2020) Xin Liang et al.   ADVANCED FUNCTIONAL MATERIALS

Chiral Carbon Dots Mimicking Topoisomerase I To Mediate the Topological Rearrangement of Supercoiled DNA Enantioselectively

(2020) Feng Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal–Organic Framework Derived Nanozymes in Biomedicine

(2020) Dongdong Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

The Fe‐N‐C Nanozyme with Both Accelerated and Inhibited Biocatalytic Activities Capable of Accessing Drug–Drug Interactions

(2020) Yuan Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Oxidase-like MOF-818 Nanozyme with High Specificity for Catalysis of Catechol Oxidation

(2020) Minghua Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ultrasmall copper-based nanoparticles for reactive oxygen species scavenging and alleviation of inflammation related diseases

(2020) Tengfei Liu et al.   Nature Communications

An Orally Administered CeO 2 @Montmorillonite Nanozyme Targets Inflammation for Inflammatory Bowel Disease Therapy

(2020) Sheng Zhao et al.   ADVANCED FUNCTIONAL MATERIALS

Cerium vanadate nanozyme with specific superoxide dismutase activity regulates mitochondrial function and ATP synthesis in neuronal cells

(2020) Namrata Singh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Self-Assembled Pd12 Coordination Cage as Photoregulated Oxidase-Like Nanozyme

(2020) Soumalya Bhattacharyya et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure and activity of nanozymes: Inspirations for de novo design of nanozymes

(2020) Zhuoran Wang et al.   Materials Today

Density Functional Theory-Based Method to Predict the Activities of Nanomaterials as Peroxidase Mimics

(2020) Xiaomei Shen et al.   ACS Catalysis

A Nanozyme‐Based Artificial Peroxisome Ameliorates Hyperuricemia and Ischemic Stroke

(2020) Juqun Xi et al.   ADVANCED FUNCTIONAL MATERIALS

Nature‐Inspired Construction of MOF@COF Nanozyme with Active Sites in Tailored Microenvironment and Pseudopodia‐Like Surface for Enhanced Bacterial Inhibition

(2020) Lu Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Coordination Number Regulation of Molybdenum Single-Atom Nanozyme Peroxidase-like Specificity

(2020) Ying Wang et al.   Chem

eg occupancy as an effective descriptor for the catalytic activity of perovskite oxide-based peroxidase mimics

(2019) Xiaoyu Wang et al.   Nature Communications

Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications

(2019) Yanyan Huang et al.   CHEMICAL REVIEWS

A Single-Atom Nanozyme for Wound Disinfection Applications

(2019) Bolong Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Porous metal-metalloporphyrin gel as catalytic binding pocket for highly efficient synergistic catalysis

(2019) Weijie Zhang et al.   Nature Communications

Single-atom nanozymes

(2019) Liang Huang et al.   Science Advances

Heme Cofactor‐Resembling Fe–N Single Site Embedded Graphene as Nanozymes to Selectively Detect H 2 O 2 with High Sensitivity

(2019) Min Su Kim et al.   ADVANCED FUNCTIONAL MATERIALS

Construction of a bioinspired laccase-mimicking nanozyme for the degradation and detection of phenolic pollutants

(2019) Jinghui Wang et al.   APPLIED CATALYSIS B-ENVIRONMENTAL

Photolyase-Like Catalytic Behavior of CeO2

(2019) Zhimin Tian et al.   NANO LETTERS

Designed heterogeneous palladium catalysts for reversible light-controlled bioorthogonal catalysis in living cells

(2018) Faming Wang et al.   Nature Communications

In vivo guiding nitrogen-doped carbon nanozyme for tumor catalytic therapy

(2018) Kelong Fan et al.   Nature Communications

Fe-N-C Artificial Enzyme: Activation of Oxygen for Dehydrogenation and Monoxygenation of Organic Substrates under Mild Condition and Cancer Therapeutic Application

(2018) Fei He et al.   ACS Applied Materials & Interfaces

Electrocatalytic nanoparticles that mimic the three dimensional geometric architecture of enzymes: Nanozymes

(2018) Tania M Benedetti et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single Cobalt Atoms Anchored on Porous N-Doped Graphene with Dual Reaction Sites for Efficient Fenton-like Catalysis

(2018) Xuning Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Novel AuNP-Based Glucose Oxidase Mimic with Enhanced Activity and Selectivity Constructed by Molecular Imprinting and O2 -Containing Nanoemulsion Embedding

(2018) Lin Fan et al.   Advanced Materials Interfaces

Photooxidase-Mimicking Nanovesicles with Superior Photocatalytic Activity and Stability Based on Amphiphilic Amino Acid and Phthalocyanine Co-Assembly

(2018) Jingjing Han et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Molecule-mediated Porous CuxO Nanoparticle Clusters with Antioxidation Activity for Ameliorating Parkinson’s Disease

(2018) Changlong Hao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Structural Mimic of Carbonic Anhydrase in a Metal-Organic Framework

(2018) Ashley M. Wright et al.   Chem

Molecular Imprinting on Inorganic Nanozymes for Hundred-fold Enzyme Specificity

(2017) Zijie Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photoswitchable Catalysis by a Nanozyme Mediated by a Light-Sensitive Cofactor

(2017) Simona Neri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Prussian Blue Nanoparticles as Multienzyme Mimetics and Reactive Oxygen Species Scavengers

(2016) Wei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Deciphering a Nanocarbon-Based Artificial Peroxidase: Chemical Identification of the Catalytically Active and Substrate-Binding Sites on Graphene Quantum Dots

(2015) Hanjun Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanism of pH-switchable peroxidase and catalase-like activities of gold, silver, platinum and palladium

(2015) Junnan Li et al.   BIOMATERIALS

Mechanisms of Oxidase and Superoxide Dismutation-like Activities of Gold, Silver, Platinum, and Palladium, and Their Alloys: A General Way to the Activation of Molecular Oxygen

(2015) Xiaomei Shen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Supramolecular regulation of bioorthogonal catalysis in cells using nanoparticle-embedded transition metal catalysts

(2015) Gulen Yesilbag Tonga et al.   Nature Chemistry

Temperature-Driven Switching of the Catalytic Activity of Artificial Glutathione Peroxidase by the Shape Transition between the Nanotubes and Vesicle-like Structures

(2014) Liang Wang et al.   LANGMUIR

An antioxidant nanozyme that uncovers the cytoprotective potential of vanadia nanowires

(2014) Amit A. Vernekar et al.   Nature Communications

Vanadium pentoxide nanoparticles mimic vanadium haloperoxidases and thwart biofilm formation

(2012) Filipe Natalio et al.   Nature Nanotechnology

Density functional theory in surface chemistry and catalysis

(2011) J. K. Norskov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Towards the computational design of solid catalysts

(2009) J. K. Nørskov et al.   Nature Chemistry