Gain‐of‐function mutations in PIEZO1 directly impair hepatic iron metabolism via the inhibition of the BMP/SMADs pathway
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Gain‐of‐function mutations in PIEZO1 directly impair hepatic iron metabolism via the inhibition of the BMP/SMADs pathway
Authors
Keywords
-
Journal
AMERICAN JOURNAL OF HEMATOLOGY
Volume 95, Issue 2, Pages 188-197
Publisher
Wiley
Online
2019-11-18
DOI
10.1002/ajh.25683
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Clinical and biological features in PIEZO1-hereditary xerocytosis and Gardos-channelopathy: A retrospective series of 126 patients
- (2019) Véronique Picard et al. HAEMATOLOGICA
- Advances in understanding the pathogenesis of red cell membrane disorders
- (2019) Achille Iolascon et al. BRITISH JOURNAL OF HAEMATOLOGY
- To induce or not to induce: the fight over hepcidin regulation
- (2019) Veena Sangkhae et al. HAEMATOLOGICA
- Multi-gene panel testing improves diagnosis and management of patients with hereditary anemias
- (2018) Roberta Russo et al. AMERICAN JOURNAL OF HEMATOLOGY
- Inherited or acquired modifiers of iron status may dramatically affect the phenotype in dehydrated hereditary stomatocytosis
- (2018) Corentin Orvain et al. EUROPEAN JOURNAL OF HAEMATOLOGY
- Structure and mechanogating mechanism of the Piezo1 channel
- (2018) Qiancheng Zhao et al. NATURE
- Piezo1 is a mechanically activated ion channel and mediates pressure induced pancreatitis
- (2018) Joelle M.-J. Romac et al. Nature Communications
- Genotype-phenotype correlation and risk stratification in a cohort of 123 hereditary stomatocytosis patients
- (2018) Andolfo Immacolata et al. AMERICAN JOURNAL OF HEMATOLOGY
- The mechanosensitive Piezo1 channel: a three‐bladed propeller‐like structure and a lever‐like mechanogating mechanism
- (2018) Qiancheng Zhao et al. FEBS Journal
- Red blood cell Gardos channel (KCNN4): the essential determinant of erythrocyte dehydration in hereditary xerocytosis
- (2017) Raphaël Rapetti-Mauss et al. HAEMATOLOGICA
- PIEZO1-R1864H rare variant accounts for a genetic phenotype-modifier role in dehydrated hereditary stomatocytosis
- (2017) Immacolata Andolfo et al. HAEMATOLOGICA
- Mechanical stretch triggers rapid epithelial cell division through Piezo1
- (2017) S. A. Gudipaty et al. NATURE
- Heterologous Expression of the Piezo1-ASIC1 Chimera Induces Mechanosensitive Currents with Properties Distinct from Piezo1
- (2017) Qiancheng Zhao et al. NEURON
- PIEZO1-R1864H rare variant accounts for a genetic phenotype-modifier role in dehydrated hereditary stomatocytosis
- (2017) Immacolata Andolfo et al. HAEMATOLOGICA
- Red blood cell Gardos channel (KCNN4): the essential determinant of erythrocyte dehydration in hereditary xerocytosis
- (2017) Raphaël Rapetti-Mauss et al. HAEMATOLOGICA
- ‘Gardos Channelopathy’: a variant of hereditary Stomatocytosis with complex molecular regulation
- (2017) Elisa Fermo et al. Scientific Reports
- Piezo type mechanosensitive ion channel component 1 functions as a regulator of the cell fate determination of mesenchymal stem cells
- (2017) Asuna Sugimoto et al. Scientific Reports
- Hereditary xerocytosis, a misleading anemia
- (2016) R. Del Orbe Barreto et al. ANNALS OF HEMATOLOGY
- Increased levels of ERFE-encoding FAM132B in patients with congenital dyserythropoietic anemia type II
- (2016) R. Russo et al. BLOOD
- Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice
- (2016) A. Nai et al. BLOOD
- New insights on hereditary erythrocyte membrane defects
- (2016) Immacolata Andolfo et al. HAEMATOLOGICA
- Signaling Cross Talk between TGF-β/Smad and Other Signaling Pathways
- (2016) Kunxin Luo Cold Spring Harbor Perspectives in Biology
- New insights on hereditary erythrocyte membrane defects
- (2016) Immacolata Andolfo et al. HAEMATOLOGICA
- Novel Gardos channel mutations linked to dehydrated hereditary stomatocytosis (xerocytosis)
- (2015) Immacolata Andolfo et al. AMERICAN JOURNAL OF HEMATOLOGY
- Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of -thalassemia
- (2015) L. Kautz et al. BLOOD
- Mutations in the Gardos channel (KCNN4) are associated with hereditary xerocytosis
- (2015) E. Glogowska et al. BLOOD
- A mutation in the Gardos channel is associated with hereditary xerocytosis
- (2015) R. Rapetti-Mauss et al. BLOOD
- Architecture of the mammalian mechanosensitive Piezo1 channel
- (2015) Jingpeng Ge et al. NATURE
- Piezo1 links mechanical forces to red blood cell volume
- (2015) Stuart M Cahalan et al. eLife
- Diagnosis and management of rare congenital nonimmune hemolytic disease
- (2015) P. G. Gallagher Hematology-American Society of Hematology Education Program
- Hereditary xerocytosis revisited
- (2014) Natasha M. Archer et al. AMERICAN JOURNAL OF HEMATOLOGY
- Human PIEZO1: Removing Inactivation
- (2013) Chilman Bae et al. BIOPHYSICAL JOURNAL
- Multiple clinical forms of dehydrated hereditary stomatocytosis arise from mutations in PIEZO1
- (2013) I. Andolfo et al. BLOOD
- Dehydrated stomatocytic anemia due to the heterozygous mutation R2456H in the mechanosensitive cation channel PIEZO1: a case report
- (2013) Boris E. Shmukler et al. BLOOD CELLS MOLECULES AND DISEASES
- Recurrent mutation in thePIEZO1gene in two families of hereditary xerocytosis with fetal hydrops
- (2013) C. Beneteau et al. CLINICAL GENETICS
- Xerocytosis is caused by mutations that alter the kinetics of the mechanosensitive channel PIEZO1
- (2013) C. Bae et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels
- (2013) Juliette Albuisson et al. Nature Communications
- Mutations in the mechanotransduction protein PIEZO1 are associated with hereditary xerocytosis
- (2012) R. Zarychanski et al. BLOOD
- Regulation of TMPRSS6 by BMP6 and iron in human cells and mice
- (2011) D. Meynard et al. BLOOD
- A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis
- (2010) D. Girelli et al. HAEMATOLOGICA
- Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
- (2010) B. Coste et al. SCIENCE
- Hereditary stomatocytosis and cation leaky red cells — Recent developments
- (2009) Lesley J. Bruce BLOOD CELLS MOLECULES AND DISEASES
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More