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Title
Regulation of TMPRSS6 by BMP6 and iron in human cells and mice
Authors
Keywords
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Journal
BLOOD
Volume 118, Issue 3, Pages 747-756
Publisher
American Society of Hematology
Online
2011-05-28
DOI
10.1182/blood-2011-04-348698
References
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Related references
Note: Only part of the references are listed.- Proteolytic processing of the serine protease matriptase-2: identification of the cleavage sites required for its autocatalytic release from the cell surface
- (2010) Marit Stirnberg et al. BIOCHEMICAL JOURNAL
- Suppression of hepatic hepcidin expression in response to acute iron deprivation is associated with an increase of matriptase-2 protein
- (2010) A.-S. Zhang et al. BLOOD
- EPO-mediated reduction in Hamp expression in vivo corrects iron deficiency anaemia in TMPRSS6 deficiency
- (2010) Hongfan Peng et al. BRITISH JOURNAL OF HAEMATOLOGY
- Regulation of Type II Transmembrane Serine Proteinase TMPRSS6 by Hypoxia-inducible Factors
- (2010) Samira Lakhal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Matriptase-2- and Proprotein Convertase-cleaved Forms of Hemojuvelin Have Different Roles in the Down-regulation of Hepcidin Expression
- (2010) Julia E. Maxson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dragon (Repulsive Guidance Molecule b) Inhibits IL-6 Expression in Macrophages
- (2010) Y. Xia et al. JOURNAL OF IMMUNOLOGY
- Identification of the First Low-Molecular-Weight Inhibitors of Matriptase-2
- (2010) Mihiret Tekeste Sisay et al. JOURNAL OF MEDICINAL CHEMISTRY
- A genome-wide association analysis of serum iron concentrations
- (2009) T. Tanaka et al. BLOOD
- BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression
- (2009) L. Kautz et al. BLOOD
- SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression
- (2009) K. Mleczko-Sanecka et al. BLOOD
- The RGM/DRAGON family of BMP co-receptors
- (2009) Elena Corradini et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Probing the substrate specificities of matriptase, matriptase-2, hepsin and DESC1 with internally quenched fluorescent peptides
- (2009) François Béliveau et al. FEBS Journal
- Bone Morphogenetic Protein Signaling Is Impaired in an Hfe Knockout Mouse Model of Hemochromatosis
- (2009) Elena Corradini et al. GASTROENTEROLOGY
- Matriptase-2 mutations in iron-refractory iron deficiency anemia patients provide new insights into protease activation mechanisms
- (2009) Andrew J. Ramsay et al. HUMAN MOLECULAR GENETICS
- Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD
- (2009) Guillem Casanovas et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels
- (2009) John C Chambers et al. NATURE GENETICS
- Lack of the bone morphogenetic protein BMP6 induces massive iron overload
- (2009) Delphine Meynard et al. NATURE GENETICS
- BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
- (2009) Billy Andriopoulos Jr et al. NATURE GENETICS
- Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium
- (2009) Santhi K Ganesh et al. NATURE GENETICS
- Common variants in TMPRSS6 are associated with iron status and erythrocyte volume
- (2009) Beben Benyamin et al. NATURE GENETICS
- Structure–activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors
- (2008) Gregory D. Cuny et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis
- (2008) A. R. Folgueras et al. BLOOD
- Iron regulates phosphorylation of Smad1/5/8 and gene expression of Bmp6, Smad7, Id1, and Atoh8 in the mouse liver
- (2008) L. Kautz et al. BLOOD
- Two nonsense mutations in the TMPRSS6 gene in a patient with microcytic anemia and iron deficiency
- (2008) F. Guillem et al. BLOOD
- The Serine Protease Matriptase-2 (TMPRSS6) Inhibits Hepcidin Activation by Cleaving Membrane Hemojuvelin
- (2008) Laura Silvestri et al. Cell Metabolism
- Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)
- (2008) Karin E Finberg et al. NATURE GENETICS
- The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency
- (2008) X. Du et al. SCIENCE
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