Efficient TALEN-mediated myostatin gene editing in goats

Production of hornless dairy cattle from genome-edited cell lines

(2016) Daniel F Carlson et al.   NATURE BIOTECHNOLOGY

Myostatin Gene Mutated Mice Induced with TALE Nucleases

(2015) Fangfang Zhou et al.   ANIMAL BIOTECHNOLOGY

Engineering large animal models of human disease

(2015) C Bruce A Whitelaw et al.   JOURNAL OF PATHOLOGY

Choosing the Right Tool for the Job: RNAi, TALEN, or CRISPR

(2015) Michael Boettcher et al.   MOLECULAR CELL

Molecular scissors and their application in genetically modified farm animals

(2015) Bjoern Petersen et al.   TRANSGENIC RESEARCH

Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system

(2015) Xiaolong Wang et al.   Scientific Reports

Gene Co-Expression Network Analysis Provides Novel Insights into Myostatin Regulation at Three Different Mouse Developmental Timepoints

(2015) Xuerong Yang et al.   PLoS One

Technology developments in biological tools for targeted genome surgery

(2014) Shahram Teimourian et al.   BIOTECHNOLOGY LETTERS

Development and Applications of CRISPR-Cas9 for Genome Engineering

(2014) Patrick D. Hsu et al.   CELL

Applications of TALENs and CRISPR/Cas9 in Human Cells and Their Potentials for Gene Therapy

(2014) Jingwen Niu et al.   MOLECULAR BIOTECHNOLOGY

Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors

(2014) Jiabiao Hu et al.   NUCLEIC ACIDS RESEARCH

Generation of RAG 1- and 2-deficient rabbits by embryo microinjection of TALENs

(2013) Jun Song et al.   CELL RESEARCH

Knockdown of endogenous myostatin promotes sheep myoblast proliferation

(2013) Chenxi Liu et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

TALEN or Cas9 – Rapid, Efficient and Specific Choices for Genome Modifications

(2013) Chuanxian Wei et al.   Journal of Genetics and Genomics

Targeted disruption of the sheep MSTN gene by engineered zinc-finger nucleases

(2013) Cunfang Zhang et al.   MOLECULAR BIOLOGY REPORTS

Knockout mice created by TALEN-mediated gene targeting

(2013) Young Hoon Sung et al.   NATURE BIOTECHNOLOGY

Targeted genome modification technologies and their applications in crop improvements

(2013) Kunling Chen et al.   PLANT CELL REPORTS

Highly Efficient Generation of GGTA1 Biallelic Knockout Inbred Mini-Pigs with TALENs

(2013) Jige Xin et al.   PLoS One

Role of stem cells in large animal genetic engineering in the TALENs?CRISPR era

(2013) Ki-Eun Park et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Muscle-specific transgenic expression of porcine myostatin propeptide enhances muscle growth in mice

(2013) Kaiyun Wang et al.   TRANSGENIC RESEARCH

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

(2013) Thomas Gaj et al.   TRENDS IN BIOTECHNOLOGY

Targeted Myostatin Gene Editing in Multiple Mammalian Species Directed by a Single Pair of TALE Nucleases

(2013) Li Xu et al.   Molecular Therapy-Nucleic Acids

TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction

(2012) Erin L. Doyle et al.   NUCLEIC ACIDS RESEARCH

Efficient targeted gene disruption in Xenopus embryos using engineered transcription activator-like effector nucleases (TALENs)

(2012) Y. Lei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developmental potential of vitrified goat oocytes following somatic cell nuclear transfer and parthenogenetic activation

(2012) Kanokwan Srirattana et al.   SMALL RUMINANT RESEARCH

Generation of human lactoferrin transgenic cloned goats using donor cells with dual markers and a modified selection procedure

(2012) Li-You An et al.   THERIOGENOLOGY

Production of myostatin-targeted goat by nuclear transfer from cultured adult somatic cells

(2012) Zheng-Rong Zhou et al.   THERIOGENOLOGY

Knockout rats generated by embryo microinjection of TALENs

(2011) Laurent Tesson et al.   NATURE BIOTECHNOLOGY

Mutations in the Myostatin gene leading to hypermuscularity in mammals: indications for a similar mechanism in fish?

(2010) A. Stinckens et al.   ANIMAL GENETICS

Molecular analysis of the first intron in the bovine myostatin gene

(2010) Yulong He et al.   MOLECULAR BIOLOGY REPORTS

Myostatin Inhibition in Muscle, but Not Adipose Tissue, Decreases Fat Mass and Improves Insulin Sensitivity

(2009) Tingqing Guo et al.   PLoS One

Cloned kids derived from caprine mammary gland epithelial cells

(2009) Y.-G. Yuan et al.   THERIOGENOLOGY

Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice

(2007) Masashi Nakatani et al.   FASEB JOURNAL