YAP Inhibition by Nuciferine via AMPK-Mediated Downregulation of HMGCR Sensitizes Pancreatic Cancer Cells to Gemcitabine

AMPK activation induced in pemetrexed‐treated cells is associated with development of drug resistance independently of target enzyme expression

(2019) Yiyang Qin et al.   Molecular Oncology

Central role of Yes-associated protein and WW-domain-containing transcriptional co-activator with PDZ-binding motif in pancreatic cancer development

(2019) Enrique Roz3engurt et al.   WORLD JOURNAL OF GASTROENTEROLOGY

The Hippo Signaling Pathway in Pancreatic Cancer

(2019) DANIEL ANSARI et al.   ANTICANCER RESEARCH

Cordycepin Inhibits Drug-resistance Non-small Cell Lung Cancer Progression by Activating AMPK Signaling Pathway

(2019) Chunli Wei et al.   PHARMACOLOGICAL RESEARCH

Downregulation of RASSF6 promotes breast cancer growth and chemoresistance through regulation of Hippo signaling

(2018) Zheng He et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Naturally occurring compounds in differentiation based therapy of cancer

(2018) Sanja Mijatović et al.   BIOTECHNOLOGY ADVANCES

Plants as sources of natural and recombinant anti-cancer agents

(2018) J.F. Buyel   BIOTECHNOLOGY ADVANCES

Inhibiting YAP expression suppresses pancreatic cancer progression by disrupting tumor-stromal interactions

(2018) Zhengdong Jiang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Corosolic acid reduces 5‑FU chemoresistance in human gastric cancer cells by activating AMPK

(2018) Jun Park et al.   Molecular Medicine Reports

VAOS, a novel vanadyl complexes of alginate saccharides, inducing apoptosis via activation of AKT-dependent ROS production in NSCLC

(2018) Ling Zhou et al.   FREE RADICAL BIOLOGY AND MEDICINE

Deciphering the metabolic role of AMPK in cancer multi-drug resistance

(2018) Wen Tan et al.   SEMINARS IN CANCER BIOLOGY

miR-590-5p suppresses hepatocellular carcinoma chemoresistance by targeting YAP1 expression

(2018) Minjiang Chen et al.   EBioMedicine

Obesity and cancer risk: Emerging biological mechanisms and perspectives

(2018) Konstantinos I. Avgerinos et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Cordycepin Augments the Chemosensitivity of Human Glioma Cells to Temozolomide by Activating AMPK and Inhibiting the AKT Signaling Pathway

(2018) Yiming Bi et al.   MOLECULAR PHARMACEUTICS

Inhibition of Cholesterol Synthesis in HepG2 Cells by GINST-Decreasing HMG-CoA Reductase Expression Via AMP-Activated Protein Kinase

(2017) Joon-Seung Han et al.   JOURNAL OF FOOD SCIENCE

Regulation of the Hippo-YAP Pathway by Glucose Sensor O-GlcNAcylation

(2017) Changmin Peng et al.   MOLECULAR CELL

Hippo pathway mediates resistance to cytotoxic drugs

(2017) Taranjit S. Gujral et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

KRAS, YAP, and obesity in pancreatic cancer: A signaling network with multiple loops

(2017) Guido Eibl et al.   SEMINARS IN CANCER BIOLOGY

Metformin and Prostate Cancer: a New Role for an Old Drug

(2017) Jessica Whitburn et al.   Current Urology Reports

Matrix stiffness induces epithelial–mesenchymal transition and promotes chemoresistance in pancreatic cancer cells

(2017) A J Rice et al.   Oncogenesis

Targeting AMPK Signaling Pathway to Overcome Drug Resistance for Cancer Therapy

(2016) Zhiyu Wang et al.   CURRENT DRUG TARGETS

AMPK activators suppress breast cancer cell growth by inhibiting DVL3-facilitated Wnt/β-catenin signaling pathway activity

(2016) Yu-Feng Zou et al.   Molecular Medicine Reports

YAP overexpression promotes the epithelial-mesenchymal transition and chemoresistance in pancreatic cancer cells

(2015) YANLI YUAN et al.   Molecular Medicine Reports

AMPK modulates Hippo pathway activity to regulate energy homeostasis

(2015) Wenqi Wang et al.   NATURE CELL BIOLOGY

Antitumor Activity of Gemcitabine Can Be Potentiated in Pancreatic Cancer through Modulation of TLR4/NF-κB signaling by 6-Shogaol

(2014) Ling Zhou et al.   AAPS Journal

Cordycepin Down-Regulates Multiple Drug Resistant (MDR)/HIF-1α through Regulating AMPK/mTORC1 Signaling in GBC-SD Gallbladder Cancer Cells

(2014) Wei-Ding Wu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metabolic control of YAP and TAZ by the mevalonate pathway

(2014) Giovanni Sorrentino et al.   NATURE CELL BIOLOGY

Energy Stress Regulates Hippo-YAP Signaling Involving AMPK-Mediated Regulation of Angiomotin-like 1 Protein

(2014) Michael DeRan et al.   Cell Reports

SIRT1 and AMPK Mediate Hypoxia-Induced Resistance of Non-Small Cell Lung Cancers to Cisplatin and Doxorubicin

(2013) D. H. Shin et al.   CANCER RESEARCH

Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility

(2013) Z. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis

(2012) B. Zhao et al.   GENES & DEVELOPMENT

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

MOBKL1A/MOBKL1B Phosphorylation by MST1 and MST2 Inhibits Cell Proliferation

(2008) Maria Praskova et al.   CURRENT BIOLOGY