Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c Mice

Vaccine candidates against leishmania under current research

(2018) Salvador Iborra et al.   Expert Review of Vaccines

Liposomal Elongation Factor-1α Triggers Effector CD4 and CD8 T Cells for Induction of Long-Lasting Protective Immunity against Visceral Leishmaniasis

(2018) Abdus Sabur et al.   Frontiers in Immunology

NH36 and F3 Antigen-Primed Dendritic Cells Show Preserved Migrating Capabilities and CCR7 Expression and F3 Is Effective in Immunotherapy of Visceral Leishmaniasis

(2018) Dirlei Nico et al.   Frontiers in Immunology

Immunoinformatics Features Linked to Leishmania Vaccine Development: Data Integration of Experimental and In Silico Studies

(2017) Rory Brito et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Vaccination with poly(D,L-lactide-co-glycolide) nanoparticles loaded with soluble Leishmania antigens and modified with a TNFα-mimicking peptide or monophosphoryl lipid A confers protection against experimental visceral leishmaniasis

(2017) Maritsa Margaroni et al.   International Journal of Nanomedicine

Mining the Proteome of Leishmania donovani for the Development of Novel MHC Class I Restricted Epitope for the Control of Visceral Leishmaniasis

(2017) Manas R. Dikhit et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Live AttenuatedLeishmania donovaniCentrin Gene–Deleted Parasites Induce IL-23–Dependent IL-17–Protective Immune Response against Visceral Leishmaniasis in a Murine Model

(2017) Antara Banerjee et al.   JOURNAL OF IMMUNOLOGY

Immuno-informatics based approaches to identify CD8+ T cell epitopes within the Leishmania donovani 3-ectonucleotidase in cured visceral leishmaniasis subjects

(2017) Vijayamahantesh et al.   MICROBES AND INFECTION

Selection strategy of phage-displayed immunogens based on an in vitro evaluation of the Th1 response of PBMCs and their potential use as a vaccine against Leishmania infantum infection

(2017) Fernanda Fonseca Ramos et al.   Parasites & Vectors

Association between mast cells, tissue remodelation and parasite burden in the skin of dogs with visceral leishmaniasis

(2017) Jamille Mirelle de Oliveira Cardoso et al.   VETERINARY PARASITOLOGY

Identification of BALB/c Immune Markers Correlated with a Partial Protection to Leishmania infantum after Vaccination with a Rationally Designed Multi-epitope Cysteine Protease A Peptide-Based Nanovaccine

(2017) Maria Agallou et al.   PLoS Neglected Tropical Diseases

A Poly(Lactic-co-Glycolic) Acid Nanovaccine Based on Chimeric Peptides from Different Leishmania infantum Proteins Induces Dendritic Cells Maturation and Promotes Peptide-Specific IFNγ-Producing CD8+ T Cells Essential for the Protection against Experimental Visceral Leishmaniasis

(2017) Evita Athanasiou et al.   Frontiers in Immunology

Identification of Potential MHC Class-II-Restricted Epitopes Derived from Leishmania donovani Antigens by Reverse Vaccinology and Evaluation of Their CD4+ T-Cell Responsiveness against Visceral Leishmaniasis

(2017) Manas Ranjan Dikhit et al.   Frontiers in Immunology

A Vaccine Therapy for Canine Visceral Leishmaniasis Promoted Significant Improvement of Clinical and Immune Status with Reduction in Parasite Burden

(2017) Bruno Mendes Roatt et al.   Frontiers in Immunology

A Chimera Containing CD4+ and CD8+ T-Cell Epitopes of the Leishmania donovani Nucleoside Hydrolase (NH36) Optimizes Cross-Protection against Leishmania amazonesis Infection

(2017) Marcus Vinícius Alves-Silva et al.   Frontiers in Immunology

A recombinant chimeric protein composed of human and mice-specific CD4+and CD8+T-cell epitopes protects against visceral leishmaniasis

(2016) V. T. Martins et al.   PARASITE IMMUNOLOGY

Characterization of the Canine MHC Class I DLA-88*50101 Peptide Binding Motif as a Prerequisite for Canine T Cell Immunotherapy

(2016) Sharon M. Barth et al.   PLoS One

Immunization with the Leishmania infantum recombinant cyclophilin protein 1 confers partial protection to subsequent parasite infection and generates specific memory T cells

(2014) G.M. Santos-Gomes et al.   VACCINE

Cross-Protective Immunity to Leishmania amazonensis is Mediated by CD4+ and CD8+ Epitopes of Leishmania donovani Nucleoside Hydrolase Terminal Domains

(2014) Dirlei Nico et al.   Frontiers in Immunology

Experimental Validation of Multi-Epitope Peptides Including Promising MHC Class I- and II-Restricted Epitopes of Four Known Leishmania infantum Proteins

(2014) Maria Agallou et al.   Frontiers in Immunology

Live Attenuated Leishmania donovani p27 Gene Knockout Parasites Are Nonpathogenic and Elicit Long-Term Protective Immunity in BALB/c Mice

(2013) R. Dey et al.   JOURNAL OF IMMUNOLOGY

Proteome-Wide Screening Reveals Immunodominance in the CD8 T Cell Response against Classical Swine Fever Virus with Antigen-Specificity Dependent on MHC Class I Haplotype Expression

(2013) Giulia Franzoni et al.   PLoS One

High Quality Long-Term CD4+ and CD8+ Effector Memory Populations Stimulated by DNA-LACK/MVA-LACK Regimen in Leishmania major BALB/c Model of Infection

(2012) Lucas Sánchez-Sampedro et al.   PLoS One

Parasite Burden in Hamsters Infected with Two Different Strains of Leishmania (Leishmania) infantum: “Leishman Donovan Units” versus Real-Time PCR

(2012) Nádia das Dores Moreira et al.   PLoS One

Performance of LBSap Vaccine after Intradermal Challenge with L. infantum and Saliva of Lu. longipalpis: Immunogenicity and Parasitological Evaluation

(2012) Bruno Mendes Roatt et al.   PLoS One

Cellular vaccination with bone marrow-derived dendritic cells pulsed with a peptide of Leishmania infantum KMP-11 and CpG oligonucleotides induces protection in a murine model of visceral leishmaniasis

(2011) Maria Agallou et al.   VACCINE

Immunity to Leishmania and the rational search for vaccines against canine leishmaniasis

(2010) Alexandre B. Reis et al.   TRENDS IN PARASITOLOGY

Adaptive Immunity against Leishmania Nucleoside Hydrolase Maps Its C-Terminal Domain as the Target of the CD4+ T Cell–Driven Protective Response

(2010) Dirlei Nico et al.   PLoS Neglected Tropical Diseases

The use of genomics in microbial vaccine development

(2009) Stefania Bambini et al.   DRUG DISCOVERY TODAY

Intracellular Replication-Deficient Leishmania donovani Induces Long Lasting Protective Immunity against Visceral Leishmaniasis

(2009) A. Selvapandiyan et al.   JOURNAL OF IMMUNOLOGY

Mining the Leishmania genome for novel antigens and vaccine candidates

(2009) Carla Herrera-Najera et al.   PROTEOMICS

The Chimerical Multi-Component Q protein from Leishmania in the absence of adjuvant protects dogs against an experimental Leishmania infantum infection

(2009) J. Carcelén et al.   VACCINE

Sand Fly Salivary Proteins Induce Strong Cellular Immunity in a Natural Reservoir of Visceral Leishmaniasis with Adverse Consequences for Leishmania

(2009) Nicolas Collin et al.   PLoS Pathogens

Systemic and compartmentalized immune response in canine visceral leishmaniasis

(2008) Alexandre Barbosa Reis et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY