Identification of Potential MHC Class-II-Restricted Epitopes Derived from Leishmania donovani Antigens by Reverse Vaccinology and Evaluation of Their CD4+ T-Cell Responsiveness against Visceral Leishmaniasis

Prediction and analysis of promiscuous T cell-epitopes derived from the vaccine candidate antigens of Leishmania donovani binding to MHC class-II alleles using in silico approach

(2017) Manju Kashyap et al.   INFECTION GENETICS AND EVOLUTION

Mining the Proteome of Leishmania donovani for the Development of Novel MHC Class I Restricted Epitope for the Control of Visceral Leishmaniasis

(2017) Manas R. Dikhit et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Structural dynamics of Casein Kinase I (CKI) from malarial parasite Plasmodium falciparum (Isolate 3D7): Insights from theoretical modelling and molecular simulations

(2017) Budheswar Dehury et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Immuno-informatics based approaches to identify CD8+ T cell epitopes within the Leishmania donovani 3-ectonucleotidase in cured visceral leishmaniasis subjects

(2017) Vijayamahantesh et al.   MICROBES AND INFECTION

Immunization with Leishmania donovani protein disulfide isomerase DNA construct induces Th1 and Th17 dependent immune response and protection against experimental visceral leishmaniasis in Balb/c mice

(2017) Ajay Amit et al.   MOLECULAR IMMUNOLOGY

Vaccine potential of HLA-A2 epitopes from Leishmania Cysteine Protease Type III (CPC)

(2017) M. R. Dikhit et al.   PARASITE IMMUNOLOGY

Computer-aided designing of immunosuppressive peptides based on IL-10 inducing potential

(2017) Gandharva Nagpal et al.   Scientific Reports

Role of pro-inflammatory cytokine IL-17 in Leishmania pathogenesis and in protective immunity by Leishmania vaccines

(2016) Antara Banerjee et al.   CELLULAR IMMUNOLOGY

Computational prediction and analysis of potential antigenic CTL epitopes in Zika virus: A first step towards vaccine development

(2016) Manas R. Dikhit et al.   INFECTION GENETICS AND EVOLUTION

Identification of B-cell Epitope of Leishmania donovani and its application in diagnosis of visceral leishmaniasis

(2016) Fauzia Jamal et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Phosphorylation of Translation Initiation Factor 2-Alpha in Leishmania donovani under Stress Is Necessary for Parasite Survival

(2016) Kumar Abhishek et al.   MOLECULAR AND CELLULAR BIOLOGY

Elevated Serum ADA Activity as a Marker for Diagnosis and Prognosis of Visceral Leishmaniasis and Post Kala-Azar Dermal Leishmaniasis in Indian Patients

(2016) Vijayamahantesh et al.   PLoS One

NetMHCpan-3.0; improved prediction of binding to MHC class I molecules integrating information from multiple receptor and peptide length datasets

(2016) Morten Nielsen et al.   Genome Medicine

Post-Genomics and Vaccine Improvement for Leishmania

(2016) Negar Seyed et al.   Frontiers in Microbiology

Combination of In Silico Methods in the Search for Potential CD4+ and CD8+ T Cell Epitopes in the Proteome of Leishmania braziliensis

(2016) Rafael de Freitas e Silva et al.   Frontiers in Immunology

Computational elucidation of potential antigenic CTL epitopes in Ebola virus

(2015) Manas R. Dikhit et al.   INFECTION GENETICS AND EVOLUTION

Leishmania donovani: impairment of the cellular immune response against recombinant ornithine decarboxylase protein as a possible evasion strategy of Leishmania in visceral leishmaniasis

(2015) Anupam Yadav et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

IL-4 contributes to failure, and colludes with IL-10 to exacerbate Leishmania donovani infection following administration of a subcutaneous leishmanial antigen vaccine

(2014) Sudipta Bhowmick et al.   BMC MICROBIOLOGY

Interleukin 17A Acts Synergistically With Interferon γ to Promote Protection Against Leishmania infantum Infection

(2014) Manuela Sales Lima Nascimento et al.   JOURNAL OF INFECTIOUS DISEASES

Th1 Stimulatory Proteins of Leishmania donovani: Comparative Cellular and Protective Responses of rTriose Phosphate Isomerase, rProtein Disulfide Isomerase and rElongation Factor-2 in Combination with rHSP70 against Visceral Leishmaniasis

(2014) Anil Kumar Jaiswal et al.   PLoS One

Combining Cationic Liposomal Delivery with MPL-TDM for Cysteine Protease Cocktail Vaccination against Leishmania donovani : Evidence for Antigen Synergy and Protection

(2014) Amrita Das et al.   PLoS Neglected Tropical Diseases

Experimental Validation of Multi-Epitope Peptides Including Promising MHC Class I- and II-Restricted Epitopes of Four Known Leishmania infantum Proteins

(2014) Maria Agallou et al.   Frontiers in Immunology

Designing of interferon-gamma inducing MHC class-II binders

(2013) Sandeep Kumar Dhanda et al.   Biology Direct

Vaccination with Leishmania Hemoglobin Receptor-Encoding DNA Protects Against Visceral Leishmaniasis

(2013) R. Guha et al.   Science Translational Medicine

Computational Elucidation of Structural Basis for Ligand Binding withLeishmania donovaniAdenosine Kinase

(2013) Rajiv K. Kar et al.   Biomed Research International

Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Christopher J L Murray et al.   LANCET

Leishmaniasis Worldwide and Global Estimates of Its Incidence

(2012) Jorge Alvar et al.   PLoS One

Immunogenicity and immune modulatory effects of in silico predictedL. donovanicandidate peptide vaccines

(2012) Mona E.E. Elfaki et al.   Human Vaccines & Immunotherapeutics

Visceral leishmaniasis: immunology and prospects for a vaccine

(2011) P.M. Kaye et al.   CLINICAL MICROBIOLOGY AND INFECTION

The development and clinical evaluation of second-generation leishmaniasis vaccines

(2011) Malcolm S. Duthie et al.   VACCINE

Vaccines for the Leishmaniases: Proposals for a Research Agenda

(2011) et al.   PLoS Neglected Tropical Diseases

Peptide binding predictions for HLA DR, DP and DQ molecules

(2010) Peng Wang et al.   BMC BIOINFORMATICS

NN-align. An artificial neural network-based alignment algorithm for MHC class II peptide binding prediction

(2009) Morten Nielsen et al.   BMC BIOINFORMATICS

IL-17 and IL-22 are associated with protection against human kala azar caused by Leishmania donovani

(2009) Maira G.R. Pitta et al.   JOURNAL OF CLINICAL INVESTIGATION

PEP-FOLD: an online resource for de novo peptide structure prediction

(2009) J. Maupetit et al.   NUCLEIC ACIDS RESEARCH

Mining the Leishmania genome for novel antigens and vaccine candidates

(2009) Carla Herrera-Najera et al.   PROTEOMICS

Computational Analysis of Cysteine Proteases (Clan CA, Family C1) of Leishmania major to Find Potential Epitopic Regions

(2009) Babak Saffari et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

CD4 T cells: fates, functions, and faults

(2008) J. Zhu et al.   BLOOD

Complexities of Assessing the Disease Burden Attributable to Leishmaniasis

(2008) Caryn Bern et al.   PLoS Neglected Tropical Diseases