Engineering the Yeast Saccharomyces cerevisiae for the Production of L-(+)-Ergothioneine

Gram-scale fermentative production of ergothioneine driven by overproduction of cysteine in Escherichia coli

(2019) Naoyuki Tanaka et al.   Scientific Reports

Metabolic engineering of microbial cell factories for production of nutraceuticals

(2019) Shuo-Fu Yuan et al.   Microbial Cell Factories

Structural and Mechanistic Basis for Anaerobic Ergothioneine Biosynthesis

(2019) Florian Leisinger et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gamma-glutamylcysteine protects ergothioneine-deficient Mycobacterium tuberculosis mutants against oxidative and nitrosative stress

(2018) C. Sao Emani et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Substrate Selectivity Check of the Ergothioneine Transporter

(2018) Julia Tschirka et al.   DRUG METABOLISM AND DISPOSITION

Ergothioneine - a diet-derived antioxidant with therapeutic potential

(2018) Barry Halliwell et al.   FEBS LETTERS

Heterologous and High Production of Ergothioneine in Escherichia coli

(2018) Ryo Osawa et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Ergothioneine production using Methylobacterium species, yeast, and fungi

(2018) Yoshiko Fujitani et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Ergothioneine production with Aspergillus oryzae

(2018) Shun Takusagawa et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Prolonging healthy aging: Longevity vitamins and proteins

(2018) Bruce N. Ames   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Understanding metabolite transport gives an upper hand in strain development

(2018) Irina Borodina   Microbial Biotechnology

Mushrooms: A rich source of the antioxidants ergothioneine and glutathione

(2017) Michael D. Kalaras et al.   FOOD CHEMISTRY

EasyClone-MarkerFree: A vector toolkit for marker-less integration of genes intoSaccharomyces cerevisiaevia CRISPR-Cas9

(2016) Mathew M Jessop-Fabre et al.   Biotechnology Journal

Gastrolatathioneine, an unusual ergothioneine derivative from an aqueous extract of “tian ma”: A natural product co-produced by plant and symbiotic fungus

(2016) Qing-Lan Guo et al.   CHINESE CHEMICAL LETTERS

Microbial production of value-added nutraceuticals

(2016) Jian Wang et al.   CURRENT OPINION IN BIOTECHNOLOGY

Localization of Xenobiotic Transporter OCTN1/SLC22A4 in Hepatic Stellate Cells and Its Protective Role in Liver Fibrosis

(2016) Yaliang Tang et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Progress in the microbial production of S-adenosyl-l-methionine

(2016) Hailong Chen et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Ergothioneine Biosynthesis and Functionality in the Opportunistic Fungal Pathogen, Aspergillus fumigatus

(2016) Kevin J. Sheridan et al.   Scientific Reports

EasyClone-MarkerFree: A vector toolkit for marker-less integration of genes intoSaccharomyces cerevisiaevia CRISPR-Cas9

(2016) Mathew M Jessop-Fabre et al.   Biotechnology Journal

Liver ergothioneine accumulation in a guinea pig model of non-alcoholic fatty liver disease. A possible mechanism of defence?

(2015) Irwin K. Cheah et al.   FREE RADICAL RESEARCH

Establishing a synthetic pathway for high-level production of 3-hydroxypropionic acid in Saccharomyces cerevisiae via β-alanine

(2015) Irina Borodina et al.   METABOLIC ENGINEERING

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Membrane transporter engineering in industrial biotechnology and whole cell biocatalysis

(2015) Douglas B. Kell et al.   TRENDS IN BIOTECHNOLOGY

Mechanistic studies of a novel C-S lyase in ergothioneine biosynthesis: the involvement of a sulfenic acid intermediate

(2015) Heng Song et al.   Scientific Reports

Production of ergothioneine by Methylobacterium species

(2015) Kabir M. Alamgir et al.   Frontiers in Microbiology

Application of synthetic biology for production of chemicals in yeastSaccharomyces cerevisiae

(2014) Mingji Li et al.   FEMS YEAST RESEARCH

Ergothioneine and melatonin attenuate oxidative stress and protect against learning and memory deficits in C57BL/6J mice treated with D-galactose

(2014) T.-Y. Song et al.   FREE RADICAL RESEARCH

GeneGenie: optimized oligomer design for directed evolution

(2014) Neil Swainston et al.   NUCLEIC ACIDS RESEARCH

Bioinformatic and Biochemical Characterizations of C–S Bond Formation and Cleavage Enzymes in the Fungus Neurospora crassa Ergothioneine Biosynthetic Pathway

(2014) Wen Hu et al.   ORGANIC LETTERS

Genetic and Metabolomic Dissection of the Ergothioneine and Selenoneine Biosynthetic Pathway in the Fission Yeast, S. pombe, and Construction of an Overproduction System

(2014) Tomáš Pluskal et al.   PLoS One

Ergothioneine Is a Secreted Antioxidant in Mycobacterium smegmatis

(2013) Carine Sao Emani et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Ergothioneine protects against neuronal injury induced by β-amyloid in mice

(2012) Nae-Cherng Yang et al.   FOOD AND CHEMICAL TOXICOLOGY

Regulation of Amino Acid, Nucleotide, and Phosphate Metabolism in Saccharomyces cerevisiae

(2012) P. O. Ljungdahl et al.   GENETICS

Ergothioneine; antioxidant potential, physiological function and role in disease

(2011) Irwin K. Cheah et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cyanobacteria produce high levels of ergothioneine

(2011) Carolin Pfeiffer et al.   FOOD CHEMISTRY

Organic Hydroperoxide Resistance Protein and Ergothioneine Compensate for Loss of Mycothiol in Mycobacterium smegmatis Mutants

(2011) P. Ta et al.   JOURNAL OF BACTERIOLOGY

In Vitro Reconstitution of Mycobacterial Ergothioneine Biosynthesis

(2010) Florian P. Seebeck   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The unusual amino acid L-ergothioneine is a physiologic cytoprotectant

(2009) B D Paul et al.   CELL DEATH AND DIFFERENTIATION

Measurement of mass, density, and volume during the cell cycle of yeast

(2009) A. K. Bryan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterologous production of secondary metabolites as pharmaceuticals in Saccharomyces cerevisiae

(2008) Beibei Huang et al.   BIOTECHNOLOGY LETTERS

Ergothioneine prevents acute lung injury in mesenteric ischemia and reperfusion injury in rats

(2008) Ömer Sakrak et al.   JOURNAL OF CRITICAL CARE

Ergothioneine Modulates Proinflammatory Cytokines and Heat Shock Protein 70 in Mesenteric Ischemia and Reperfusion Injury

(2007) Omer Sakrak et al.   JOURNAL OF SURGICAL RESEARCH