Salinomycin inhibits metastatic colorectal cancer growth and interferes with Wnt/β-catenin signaling in CD133+ human colorectal cancer cells

Salinomycin inhibits growth of pancreatic cancer and cancer cell migration by disruption of actin stress fiber integrity

(2015) Miriam Schenk et al.   CANCER LETTERS

Intradermal delivery of DNA encoding HCV NS3 and perforin elicits robust cell-mediated immunity in mice and pigs

(2015) B Grubor-Bauk et al.   GENE THERAPY

Salinomycin decreases doxorubicin resistance in hepatocellular carcinoma cells by inhibiting the β-catenin/TCF complex association via FOXO3a activation

(2015) Yue Zhou et al.   Oncotarget

Inhibition of Wnt signaling and cancer stem cells

(2015) Desheng Lu et al.   Oncotarget

Salinomycin Suppresses LRP6 Expression and Inhibits Both Wnt/β-catenin and mTORC1 Signaling in Breast and Prostate Cancer Cells

(2014) Wenyan Lu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Oncogenic KRAS signalling promotes the Wnt/β-catenin pathway through LRP6 in colorectal cancer

(2014) E Lemieux et al.   ONCOGENE

The Synergistic In Vitro and In Vivo Antitumor Effect of Combination Therapy with Salinomycin and 5-Fluorouracil against Hepatocellular Carcinoma

(2014) Fan Wang et al.   PLoS One

Inhibition of Autophagic Flux by Salinomycin Results in Anti-Cancer Effect in Hepatocellular Carcinoma Cells

(2014) Johannes Klose et al.   PLoS One

Roles of Wnt/β-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment

(2014) J Mao et al.   Cell Death & Disease

LGR5 positivity defines stem-like cells in colorectal cancer

(2013) Daniela Hirsch et al.   CARCINOGENESIS

Mechanism of action of salinomycin on growth and migration in pancreatic cancer cell lines

(2013) Lei He et al.   PANCREATOLOGY

Differential Effects of Drugs Targeting Cancer Stem Cell (CSC) and Non-CSC Populations on Lung Primary Tumors and Metastasis

(2013) Leyre Larzabal et al.   PLoS One

Fibronectin extra domain A (EDA) sustains CD133+/CD44+ subpopulation of colorectal cancer cells

(2013) Juanjuan Ou et al.   Stem Cell Research

Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species

(2013) Jin Zhou et al.   TOXICOLOGY LETTERS

Impact of Salinomycin on human cholangiocarcinoma: induction of apoptosis and impairment of tumor cell proliferation in vitro

(2012) Thorsten Lieke et al.   BMC CANCER

Salinomycin as a Drug for Targeting Human Cancer Stem Cells

(2012) Cord Naujokat et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Salinomycin Induces Autophagy in Colon and Breast Cancer Cells with Concomitant Generation of Reactive Oxygen Species

(2012) Berlinda Verdoodt et al.   PLoS One

Salinomycin Inhibits Proliferation and Induces Apoptosis of Human Hepatocellular Carcinoma Cells In Vitro and In Vivo

(2012) Fan Wang et al.   PLoS One

Salinomycin Selectively Targets ‘CD133+’ Cell Subpopulations and Decreases Malignant Traits in Colorectal Cancer Lines

(2011) Tao-Tao Dong et al.   ANNALS OF SURGICAL ONCOLOGY

Combination of salinomycin and gemcitabine eliminates pancreatic cancer cells

(2011) Guan-Nan Zhang et al.   CANCER LETTERS

The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse

(2011) Anna Merlos-Suárez et al.   Cell Stem Cell

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

(2011) Wim de Lau et al.   NATURE

Salinomycin inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells

(2011) Desheng Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/ -catenin signaling

(2011) K. S. Carmon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Simvastatin Induces Apoptosis and Alters Cytoskeleton in Endometrial Stromal Cells

(2010) Anna Sokalska et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Salinomycin in cancer: A new mission for an old agent

(2010) Naujokat   Molecular Medicine Reports

The Stem Cell Marker CD133 Associates with Enhanced Colony Formation and Cell Motility in Colorectal Cancer

(2010) Tarek M. A. Elsaba et al.   PLoS One

Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

(2009) Piyush B. Gupta et al.   CELL