Intradermal delivery of DNA encoding HCV NS3 and perforin elicits robust cell-mediated immunity in mice and pigs

A Multiantigenic DNA Vaccine That Induces Broad Hepatitis C Virus-Specific T-Cell Responses in Mice

(2015) Jason Gummow et al.   JOURNAL OF VIROLOGY

DNA vaccines encoding membrane-bound or secreted forms of heat shock protein 70 exhibit improved potency

(2014) Tamsin J. Garrod et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Sticker shock and the price of new therapies for hepatitis C: Is it worth it?

(2014) Nancy S. Reau et al.   HEPATOLOGY

A novel challenge model to evaluate the efficacy of hepatitis C virus vaccines in mice

(2014) Wenbo Yu et al.   VACCINE

Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack

(2013) J. A. Lopez et al.   BLOOD

Induction of antigen-positive cell death by the expression of Perforin, but not DTa, from a DNA vaccine enhances the immune response

(2013) Tessa Gargett et al.   IMMUNOLOGY AND CELL BIOLOGY

Current progress in development of hepatitis C virus vaccines

(2013) T Jake Liang   NATURE MEDICINE

Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death

(2013) Dimitry Ofengeim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Eat-Me: Autophagy, Phagocytosis, and Reactive Oxygen Species Signaling

(2012) Philip J. Vernon et al.   ANTIOXIDANTS & REDOX SIGNALING

Dendritic cell-based immunity and vaccination against hepatitis C virus infection

(2012) Yun Zhou et al.   IMMUNOLOGY

Complete Definition of Immunological Correlates of Protection and Clearance of Hepatitis C Virus Infection: A Relevant Pending Task for Vaccine Development

(2012) Liz Alvarez-Lajonchere et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Rotaviral Enterotoxin Nonstructural Protein 4 Targets Mitochondria for Activation of Apoptosis during Infection

(2012) Rahul Bhowmick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The future of human DNA vaccines

(2012) Lei Li et al.   JOURNAL OF BIOTECHNOLOGY

The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice

(2012) Santiago Zelenay et al.   JOURNAL OF CLINICAL INVESTIGATION

Discrimination between primary necrosis and apoptosis by necrostatin-1 in Annexin V-positive/propidium iodide-negative cells

(2011) Hirofumi Sawai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

(2011) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Protection from Endogenous Perforin: Glycans and the C Terminus Regulate Exocytic Trafficking in Cytotoxic Lymphocytes

(2011) Amelia J. Brennan et al.   IMMUNITY

Innate and adaptive immune responses to cell death

(2011) Kenneth L. Rock et al.   IMMUNOLOGICAL REVIEWS

Progress in the development of preventive and therapeutic vaccines for hepatitis C virus

(2011) Joseph Torresi et al.   JOURNAL OF HEPATOLOGY

Enhanced and Sustained CD8+ T Cell Responses with an Adenoviral Vector-Based Hepatitis C Virus Vaccine Encoding NS3 Linked to the MHC Class II Chaperone Protein Invariant Chain

(2011) M. Mikkelsen et al.   JOURNAL OF IMMUNOLOGY

The pig: a model for human infectious diseases

(2011) François Meurens et al.   TRENDS IN MICROBIOLOGY

DNA vaccines: an historical perspective and view to the future

(2010) Margaret A. Liu   IMMUNOLOGICAL REVIEWS

The structural basis for membrane binding and pore formation by lymphocyte perforin

(2010) Ruby H. P. Law et al.   NATURE

Comparative ability of IL-12 and IL-28B to regulate Treg populations and enhance adaptive cellular immunity

(2009) M. P. Morrow et al.   BLOOD

Apo2L/TRAIL Inhibits Tumor Growth and Bone Destruction in a Murine Model of Multiple Myeloma

(2009) A. Labrinidis et al.   CLINICAL CANCER RESEARCH

DNA vaccine manufacture: scale and quality

(2009) Ying Cai et al.   Expert Review of Vaccines

Identification of a dendritic cell receptor that couples sensing of necrosis to immunity

(2009) David Sancho et al.   NATURE

Identification of RIP1 kinase as a specific cellular target of necrostatins

(2008) Alexei Degterev et al.   Nature Chemical Biology