CAGE-miR-140-5p-Wnt1 Axis Regulates Autophagic Flux, Tumorigenic Potential of Mouse Colon Cancer Cells and Cellular Interactions Mediated by Exosomes

Multiple myeloma cell-derived IL-32γ increases the immunosuppressive function of macrophages by promoting indoleamine 2,3-dioxygenase (IDO) expression

(2019) Haimeng Yan et al.   CANCER LETTERS

CAFs and TGF-β Signaling Activation by Mast Cells Contribute to Resistance to Gemcitabine/Nabpaclitaxel in Pancreatic Cancer

(2019) Letizia Porcelli et al.   Cancers

Exosomes from differentially activated macrophages influence dormancy or resurgence of breast cancer cells within bone marrow stroma

(2019) Nykia D. Walker et al.   Cell Death & Disease

MIR-1265 regulates cellular proliferation and apoptosis by targeting calcium binding protein 39 in gastric cancer and, thereby, impairing oncogenic autophagy

(2019) Zhipeng Xu et al.   CANCER LETTERS

Alternatively activated macrophage-derived secretome stimulates ovarian cancer spheroid spreading through a JAK2/STAT3 pathway

(2019) Kaitlin C. Fogg et al.   CANCER LETTERS

Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma

(2019) Peiwen Chen et al.   CANCER CELL

MiR-135-5p-p62 Axis Regulates Autophagic Flux, Tumorigenic Potential, and Cellular Interactions Mediated by Extracellular Vesicles During Allergic Inflammation

(2019) Misun Kim et al.   Frontiers in Immunology

HDAC4 regulates vascular inflammation via activation of autophagy

(2018) Di Yang et al.   CARDIOVASCULAR RESEARCH

Activation of WNT/β-catenin signaling results in resistance to a dual PI3K/mTOR inhibitor in colorectal cancer cells harboring PIK3CA mutations

(2018) Ye-Lim Park et al.   INTERNATIONAL JOURNAL OF CANCER

The vitamin D receptor regulates miR-140-5p and targets the MAPK pathway in bone development

(2018) Wenting Luo et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Abrus agglutinin stimulates BMP-2-dependent differentiation through autophagic degradation of β-catenin in colon cancer stem cells

(2018) Prashanta K. Panda et al.   MOLECULAR CARCINOGENESIS

Phosphorylation of ULK1 by AMPK is essential for mouse embryonic stem cell self-renewal and pluripotency

(2018) Jiaqi Gong et al.   Cell Death & Disease

Inhibition of mTOR complex 2 restrains tumor angiogenesis in multiple myeloma

(2018) Aurelia Lamanuzzi et al.   Oncotarget

Autophagy processes are dependent on EGF receptor signaling

(2018) Vincenzo De Iuliis et al.   Oncotarget

Rapamycin Synergizes with Cisplatin in Antiendometrial Cancer Activation by Improving IL-27–Stimulated Cytotoxicity of NK Cells

(2018) Wen-Jie Zhou et al.   NEOPLASIA

Exosomes derived from PEDF modified adipose-derived mesenchymal stem cells ameliorate cerebral ischemia-reperfusion injury by regulation of autophagy and apoptosis

(2018) Xiao Huang et al.   EXPERIMENTAL CELL RESEARCH

CCN6-mediated MMP-9 activation enhances metastatic potential of human chondrosarcoma

(2018) Huey-En Tzeng et al.   Cell Death & Disease

Human mast cells promote colon cancer growth via bidirectional crosstalk: studies in 2D and 3D coculture models

(2018) Yingxin Yu et al.   OncoImmunology

HDAC6 differentially regulates autophagy in stem-like versus differentiated cancer cells

(2018) Tanveer Sharif et al.   Autophagy

APC-activated long noncoding RNA inhibits colorectal carcinoma pathogenesis through reduction of exosome production

(2018) Feng-Wei Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Tumor-promoting effects of pancreatic cancer cell exosomes on THP-1-derived macrophages

(2018) Samuel S. Linton et al.   PLoS One

CAGE Binds to Beclin1, Regulates Autophagic Flux and CAGE-Derived Peptide Confers Sensitivity to Anti-cancer Drugs in Non-small Cell Lung Cancer Cells

(2018) Minjeong Yeon et al.   Frontiers in Oncology

Exosomes derived from miR-181-5p-modified adipose-derived mesenchymal stem cells prevent liver fibrosis via autophagy activation

(2017) Ying Qu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Macrophage-derived IL-10 mediates mucosal repair by epithelial WISP-1 signaling

(2017) Miguel Quiros et al.   JOURNAL OF CLINICAL INVESTIGATION

DDX53 Regulates Cancer Stem Cell-Like Properties by Binding to SOX-2

(2017) Youngmi Kim et al.   MOLECULES AND CELLS

Phthalate exposure promotes chemotherapeutic drug resistance in colon cancer cells

(2017) Hsin-Pao Chen et al.   Oncotarget

miR-122-SOCS1-JAK2 axis regulates allergic inflammation and allergic inflammation-promoted cellular interactions

(2017) Kyeonga Noh et al.   Oncotarget

PIKfyve inhibition increases exosome release and induces secretory autophagy

(2016) Nina Pettersen Hessvik et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Histone Deacetylase-3/CAGE Axis Targets EGFR Signaling and Regulates the Response to Anti-Cancer Drugs

(2016)   MOLECULES AND CELLS

Prodigiosin inhibits Wnt/β-catenin signaling and exerts anticancer activity in breast cancer cells

(2016) Zhongyuan Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exosomes derived from gefitinib-treated EGFR-mutant lung cancer cells alter cisplatin sensitivity via up-regulating autophagy

(2016) Xiao-Qiu Li et al.   Oncotarget

Lower Beclin 1 downregulates HER2 expression to enhance tamoxifen sensitivity and predicts a favorable outcome for ER positive breast cancer

(2016) Yu Gu et al.   Oncotarget

Lin28B/Let-7 Regulates Expression of Oct4 and Sox2 and Reprograms Oral Squamous Cell Carcinoma Cells to a Stem-like State

(2015) C.-S. Chien et al.   CANCER RESEARCH

MicroRNA-140 Provides Robustness to the Regulation of Hypertrophic Chondrocyte Differentiation by the PTHrP-HDAC4 Pathway

(2015) Garyfallia Papaioannou et al.   JOURNAL OF BONE AND MINERAL RESEARCH

MicroRNA-451 regulates stemness of side population cells via PI3K/Akt/mTOR signaling pathway in multiple myeloma

(2015) Juan Du et al.   Oncotarget

Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling

(2015) Rebecca Lamb et al.   Oncotarget

MiR-148b suppresses cell proliferation and invasion in hepatocellular carcinoma by targeting WNT1/β-catenin pathway

(2015) Jun-gang Zhang et al.   Scientific Reports

Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity

(2014) Michelle Cicchini et al.   Autophagy

HDAC3 acts as a negative regulator of angiogenesis

(2014) Deokbum Park et al.   BMB Reports

Mast cell exosomes promote lung adenocarcinoma cell proliferation ¿ role of KIT-stem cell factor signaling

(2014) Hui Xiao et al.   Cell Communication and Signaling

miR-326-Histone Deacetylase-3 Feedback Loop Regulates the Invasion and Tumorigenic and Angiogenic Response to Anti-cancer Drugs

(2014) Youngmi Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Autophagic Flux by Salinomycin Results in Anti-Cancer Effect in Hepatocellular Carcinoma Cells

(2014) Johannes Klose et al.   PLoS One

MicroRNAs-140-5p/140-3p Modulate Leydig Cell Numbers in the Developing Mouse Testis

(2013) J. Rakoczy et al.   BIOLOGY OF REPRODUCTION

miR-200b and Cancer/Testis Antigen CAGE Form a Feedback Loop to Regulate the Invasion and Tumorigenic and Angiogenic Responses of a Cancer Cell Line to Microtubule-targeting Drugs

(2013) Youngmi Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SQSTM1/p62 Interacts with HDAC6 and Regulates Deacetylase Activity

(2013) Jin Yan et al.   PLoS One

M2 Macrophages Activate WNT Signaling Pathway in Epithelial Cells: Relevance in Ulcerative Colitis

(2013) Jesús Cosín-Roger et al.   PLoS One

Leptin-induced Epithelial-Mesenchymal Transition in Breast Cancer Cells Requires β-Catenin Activation via Akt/GSK3- and MTA1/Wnt1 Protein-dependent Pathways

(2012) Dan Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SOX2 Gene Regulates the Transcriptional Network of Oncogenes and Affects Tumorigenesis of Human Lung Cancer Cells

(2012) Si Chen et al.   PLoS One

Crosstalk between Mast Cells and Pancreatic Cancer Cells Contributes to Pancreatic Tumor Progression

(2010) M. J. Strouch et al.   CLINICAL CANCER RESEARCH

The Cancer/Testis Antigen CAGE with Oncogenic Potential Stimulates Cell Proliferation by Up-regulating Cyclins D1 and E in an AP-1- and E2F-dependent Manner

(2010) Elaine Por et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer/Testis Antigen CAGE Exerts Negative Regulation on p53 Expression through HDAC2 and Confers Resistance to Anti-cancer Drugs

(2010) Youngmi Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY