Defective Excitatory/Inhibitory Synaptic Balance and Increased Neuron Apoptosis in a Zebrafish Model of Dravet Syndrome

Drug repurposing for Dravet syndrome in scn1Lab −/− mutant zebrafish

(2019) Jo Sourbron et al.   EPILEPSIA

Tuning GABAergic Inhibition: Gephyrin Molecular Organization and Functions

(2019) Rocco Pizzarelli et al.   NEUROSCIENCE

Non-canonical mTOR-Independent Role of DEPDC5 in Regulating GABAergic Network Development

(2018) Amrutha Swaminathan et al.   CURRENT BIOLOGY

Alterations of apoptosis and autophagy in developing brain of rats with epilepsy: Changes in LC3, P62, Beclin-1 and Bcl-2 levels

(2018) Qinrui Li et al.   NEUROSCIENCE RESEARCH

Excitatory synaptic dysfunction cell-autonomously decreases inhibitory inputs and disrupts structural and functional plasticity

(2018) Hai-yan He et al.   Nature Communications

γ-Aminobutyric acid receptor alpha 1 subunit loss of function causes genetic generalized epilepsy by impairing inhibitory network neurodevelopment

(2018) Éric Samarut et al.   EPILEPSIA

Spatial patterning of excitatory and inhibitory neuropil territories during spinal circuit development

(2017) Qing Yan et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Serotonergic Modulation as Effective Treatment for Dravet Syndrome in a Zebrafish Mutant Model

(2016) Jo Sourbron et al.   ACS Chemical Neuroscience

Plasticity of Hippocampal Excitatory-Inhibitory Balance: Missing the Synaptic Control in the Epileptic Brain

(2016) Christian Bonansco et al.   NEURAL PLASTICITY

Animal models in epilepsy research: legacies and new directions

(2015) Brian P Grone et al.   NATURE NEUROSCIENCE

Cross-talk and regulation between glutamate and GABAB receptors

(2015) Sriharsha Kantamneni   Frontiers in Cellular Neuroscience

Pharmacological Characterization of an Antisense Knockdown Zebrafish Model of Dravet Syndrome: Inhibition of Epileptic Seizures by the Serotonin Agonist Fenfluramine

(2015) Yifan Zhang et al.   PLoS One

Transgenic tools to characterize neuronal properties of discrete populations of zebrafish neurons

(2013) C. Satou et al.   DEVELOPMENT

Synaptic inhibition and ^|^gamma;-aminobutyric acid in the mammalian central nervous system

(2013) Kunihiko OBATA   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Of fish and men: using zebrafish to fight human diseases

(2013) Julien Ablain et al.   TRENDS IN CELL BIOLOGY

Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment

(2013) Scott C. Baraban et al.   Nature Communications

Generation of Multiple Classes of V0 Neurons in Zebrafish Spinal Cord: Progenitor Heterogeneity and Temporal Control of Neuronal Diversity

(2012) C. Satou et al.   JOURNAL OF NEUROSCIENCE

Optimization of a GCaMP Calcium Indicator for Neural Activity Imaging

(2012) J. Akerboom et al.   JOURNAL OF NEUROSCIENCE

Epilepsy as a Neurodevelopmental Disorder

(2012) Yuri Bozzi et al.   Frontiers in Psychiatry

Dravet syndrome history

(2011) CHARLOTTE DRAVET   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

A case of SUDEP in a patient with Dravet syndrome with SCN1A mutation

(2010) François Le Gal et al.   EPILEPSIA

Scn1a missense mutation causes limbic hyperexcitability and vulnerability to experimental febrile seizures

(2010) Yukihiro Ohno et al.   NEUROBIOLOGY OF DISEASE

Glycinergic tonic inhibition of hippocampal neurons with depolarizing GABAergic transmission elicits histopathological signs of temporal lobe epilepsy

(2008) Sabrina A. Eichler et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Modulators of neuronal cell death in epilepsy

(2007) D HENSHALL et al.   CURRENT OPINION IN PHARMACOLOGY