Subversion of Host Cell Mitochondria by RSV to Favor Virus Production is Dependent on Inhibition of Mitochondrial Complex I and ROS Generation

Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production

(2019) MengJie Hu et al.   eLife

Chronic Supplementation With a Mitochondrial Antioxidant (MitoQ) Improves Vascular Function in Healthy Older AdultsNovelty and Significance

(2018) Matthew J. Rossman et al.   HYPERTENSION

Mitochondria-targeted antioxidant therapy with MitoQ ameliorates aortic stiffening in old mice

(2018) Rachel A. Gioscia-Ryan et al.   JOURNAL OF APPLIED PHYSIOLOGY

Osteopontin plays a pivotal role in increasing severity of respiratory syncytial virus infection

(2018) Viviana Sampayo-Escobar et al.   PLoS One

The mitochondrially targeted antioxidant MitoQ protects the intestinal barrier by ameliorating mitochondrial DNA damage via the Nrf2/ARE signaling pathway

(2018) Qiongyuan Hu et al.   Cell Death & Disease

MitoQ supplementation prevent long-term impact of maternal smoking on renal development, oxidative stress and mitochondrial density in male mice offspring

(2018) Suporn Sukjamnong et al.   Scientific Reports

Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study

(2017) Ting Shi et al.   LANCET

Replication defective viral genomes exploit a cellular pro-survival mechanism to establish paramyxovirus persistence

(2017) Jie Xu et al.   Nature Communications

Product review on the monoclonal antibody palivizumab for prevention of respiratory syncytial virus infection

(2017) Bernhard Resch   Human Vaccines & Immunotherapeutics

Studies of Hematopoietic Cell Differentiation with a Ratiometric and Reversible Sensor of Mitochondrial Reactive Oxygen Species

(2016) Amandeep Kaur et al.   ANTIOXIDANTS & REDOX SIGNALING

Unraveling the complexity of mitochondrial complex I assembly: A dynamic process

(2016) Laura Sánchez-Caballero et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Structure of Mammalian Respiratory Supercomplex I 1 III 2 IV 1

(2016) Meng Wu et al.   CELL

Mutations in the accessory subunitNDUFB10result in isolated complex I deficiency and illustrate the critical role of intermembrane space import for complex I holoenzyme assembly

(2016) Marisa W. Friederich et al.   HUMAN MOLECULAR GENETICS

Structure of mammalian respiratory complex I

(2016) Jiapeng Zhu et al.   NATURE

Accessory subunits are integral for assembly and function of human mitochondrial complex I

(2016) David A. Stroud et al.   NATURE

New Host Factors Important for Respiratory Syncytial Virus (RSV) Replication Revealed by a Novel Microfluidics Screen for Interactors of Matrix (M) Protein

(2015) Sarit Kipper et al.   MOLECULAR & CELLULAR PROTEOMICS

Respiratory syncytial virus (RSV) and its propensity for causing bronchiolitis

(2014) Raymond J Pickles et al.   JOURNAL OF PATHOLOGY

Proteomic analysis of mitochondria in respiratory epithelial cells infected with human respiratory syncytial virus and functional implications for virus and cell biology

(2014) Diane C. Munday et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Mitochondrial impairment triggers cytosolic oxidative stress and cell death following proteasome inhibition

(2014) Sunita Maharjan et al.   Scientific Reports

An Overview of Respiratory Syncytial Virus

(2014) Jia Meng et al.   PLoS Pathogens

Relative Respiratory Syncytial Virus Cytopathogenesis in Upper and Lower Respiratory Tract Epithelium

(2013) Hong Guo-Parke et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

p32 protein levels are integral to mitochondrial and endoplasmic reticulum morphology, cell metabolism and survival

(2013) MengJie Hu et al.   BIOCHEMICAL JOURNAL

Viral degradasome hijacks mitochondria to suppress innate immunity

(2013) Ramansu Goswami et al.   CELL RESEARCH

The Mitochondrial Antiviral Protein MAVS Associates with NLRP3 and Regulates Its Inflammasome Activity

(2013) S. Park et al.   JOURNAL OF IMMUNOLOGY

Human respiratory syncytial virus N, P and M protein interactions in HEK-293T cells

(2013) Andressa P. Oliveira et al.   VIRUS RESEARCH

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Rafael Lozano et al.   LANCET

Respiratory syncytial virus vaccine development

(2011) Julia L Hurwitz   Expert Review of Vaccines

Animal and human studies with the mitochondria-targeted antioxidant MitoQ

(2010) Robin A.J. Smith et al.   Annals of the New York Academy of Sciences

Pharmacologic Advances in the Treatment and Prevention of Respiratory Syncytial Virus

(2010) Kerry M. Empey et al.   CLINICAL INFECTIOUS DISEASES

NDUFA10 mutations cause complex I deficiency in a patient with Leigh disease

(2010) Saskia J G Hoefs et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Quantitative proteome profiling of respiratory virus-infected lung epithelial cells

(2010) Angela van Diepen et al.   Journal of Proteomics

Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

(2010) Harish Nair et al.   LANCET

The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients

(2010) Edward J. Gane et al.   LIVER INTERNATIONAL

Newcastle Disease Virus Infection Promotes Bax Redistribution to Mitochondria and Cell Death in HeLa Cells

(2009) Aidin Molouki et al.   INTERVIROLOGY

Generation of Reactive Oxygen Species by Mitochondrial Complex I: Implications in Neurodegeneration

(2008) Romana Fato et al.   NEUROCHEMICAL RESEARCH

Respiratory syncytial virus uses a Vps4-independent budding mechanism controlled by Rab11-FIP2

(2008) T. J. Utley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA