Viral degradasome hijacks mitochondria to suppress innate immunity

The Interactome of the Human Respiratory Syncytial Virus NS1 Protein Highlights Multiple Effects on Host Cell Biology

(2012) W. Wu et al.   JOURNAL OF VIROLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Respiratory Syncytial Virus NS1 Protein Colocalizes with Mitochondrial Antiviral Signaling Protein MAVS following Infection

(2012) Sandhya Boyapalle et al.   PLoS One

Respiratory Syncytial Virus Matrix Protein Induces Lung Epithelial Cell Cycle Arrest through a p53 Dependent Pathway

(2012) Tao Bian et al.   PLoS One

Orchestrating the interferon antiviral response through the mitochondrial antiviral signaling (MAVS) adapter

(2011) S Mehdi Belgnaoui et al.   CURRENT OPINION IN IMMUNOLOGY

Pathogen Recognition by the Innate Immune System

(2011) Himanshu Kumar et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Molecular mechanisms and physiologic functions of mitochondrial dynamics

(2011) H. Otera et al.   JOURNAL OF BIOCHEMISTRY

A novel mechanism for the inhibition of interferon regulatory factor-3-dependent gene expression by human respiratory syncytial virus NS1 protein

(2011) J. Ren et al.   JOURNAL OF GENERAL VIROLOGY

Multiple Functional Domains and Complexes of the Two Nonstructural Proteins of Human Respiratory Syncytial Virus Contribute to Interferon Suppression and Cellular Location

(2011) S. Swedan et al.   JOURNAL OF VIROLOGY

Characterization of the Interaction between Human Respiratory Syncytial Virus and the Cell Cycle in Continuous Cell Culture and Primary Human Airway Epithelial Cells

(2011) W. Wu et al.   JOURNAL OF VIROLOGY

Negative Regulation of Interferon-β Gene Expression during Acute and Persistent Virus Infections

(2011) Junqiang Ye et al.   PLoS One

Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus

(2011) S. M. Horner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Viral apoptosis is induced by IRF-3-mediated activation of Bax

(2010) Saurabh Chattopadhyay et al.   EMBO JOURNAL

The ISG56/IFIT1 Gene Family

(2010) Volker Fensterl et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Quantitative Proteomic Analysis of A549 Cells Infected with Human Respiratory Syncytial Virus

(2010) Diane C. Munday et al.   MOLECULAR & CELLULAR PROTEOMICS

Virus-Infection or 5′ppp-RNA Activates Antiviral Signal through Redistribution of IPS-1 Mediated by MFN1

(2010) Kazuhide Onoguchi et al.   PLoS Pathogens

Interferons and viral infections

(2009) Volker Fensterl et al.   BIOFACTORS

Mitochondrial dynamics regulate the RIG-I-like receptor antiviral pathway

(2009) Céline Castanier et al.   EMBO REPORTS

Interactions between the endoplasmic reticulum, mitochondria, plasma membrane and other subcellular organelles

(2009) Magdalena Lebiedzinska et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Human Respiratory Syncytial Virus Nonstructural Protein NS2 Antagonizes the Activation of Beta Interferon Transcription by Interacting with RIG-I

(2009) Z. Ling et al.   JOURNAL OF VIROLOGY

Respiratory Syncytial Virus Nonstructural Proteins Decrease Levels of Multiple Members of the Cellular Interferon Pathways

(2009) S. Swedan et al.   JOURNAL OF VIROLOGY

Cell Cycle Arrest by Transforming Growth Factor  1 Enhances Replication of Respiratory Syncytial Virus in Lung Epithelial Cells

(2009) J. D. Gibbs et al.   JOURNAL OF VIROLOGY

GM1-Ganglioside Accumulation at the Mitochondria-Associated ER Membranes Links ER Stress to Ca2+-Dependent Mitochondrial Apoptosis

(2009) Renata Sano et al.   MOLECULAR CELL

Recognition of viral nucleic acids in innate immunity

(2009) Mitsutoshi Yoneyama et al.   REVIEWS IN MEDICAL VIROLOGY

MAM: more than just a housekeeper

(2009) Teruo Hayashi et al.   TRENDS IN CELL BIOLOGY

Negative regulation of cytoplasmic RNA-mediated antiviral signaling

(2008) Akihiko Komuro et al.   CYTOKINE

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE

Crystal structure of human IPS-1/MAVS/VISA/Cardif caspase activation recruitment domain

(2008) Jane A Potter et al.   BMC STRUCTURAL BIOLOGY

The interplay between viruses and innate immune signaling: Recent insights and therapeutic opportunities

(2007) Leonie Unterholzner et al.   BIOCHEMICAL PHARMACOLOGY

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY