The triptolide derivative MRx102 inhibits Wnt pathway activation and has potent anti-tumor effects in lung cancer
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Title
The triptolide derivative MRx102 inhibits Wnt pathway activation and has potent anti-tumor effects in lung cancer
Authors
Keywords
MRx102, Triptolide, Lung cancer, Metastasis, Wnt
Journal
BMC CANCER
Volume 16, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-07-11
DOI
10.1186/s12885-016-2487-7
References
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Related references
Note: Only part of the references are listed.- Cancer statistics, 2014
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- Recent Clinical Advances in Lung Cancer Management
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- Triptolide: Progress on research in pharmacodynamics and toxicology
- (2014) Xiao-Jiaoyang Li et al. JOURNAL OF ETHNOPHARMACOLOGY
- Wnt Signaling Pathway in Non-Small Cell Lung Cancer
- (2013) D. J. Stewart JNCI-Journal of the National Cancer Institute
- Herbal compound triptolide synergistically enhanced antitumor activity of amino-terminal fragment of urokinase
- (2013) Yuli Lin et al. Molecular Cancer
- Wnt Pathway Activation Predicts Increased Risk of Tumor Recurrence in Patients With Stage I Nonsmall Cell Lung Cancer
- (2012) Mark Shapiro et al. ANNALS OF SURGERY
- Non-Small Cell Lung Cancer: Epidemiology, Risk Factors, Treatment, and Survivorship
- (2012) Julian R. Molina et al. MAYO CLINIC PROCEEDINGS
- Triptolide and its expanding multiple pharmacological functions
- (2011) Qiuyan Liu INTERNATIONAL IMMUNOPHARMACOLOGY
- MRx102, a triptolide derivative, has potent antileukemic activity in vitro and in a murine model of AML
- (2011) B Z Carter et al. LEUKEMIA
- Survival by histologic subtype in stage IV nonsmall cell lung cancer based on data from the Surveillance, Epidemiology and End Results Program
- (2011) Karynsa Cetin et al. Clinical Epidemiology
- Early stage and locally advanced (non-metastatic) non-small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
- (2010) L. Crino et al. ANNALS OF ONCOLOGY
- Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
- (2009) Bryan T. MacDonald et al. DEVELOPMENTAL CELL
- Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression
- (2009) Zhipeng Wang et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Triptolide exerts anti-tumor effect on oral cancer and KB cells in vitro and in vivo
- (2009) Yuan-Wu Chen et al. ORAL ONCOLOGY
- Triptolide sensitizes AML cells to TRAIL-induced apoptosis via decrease of XIAP and p53-mediated increase of DR5
- (2008) B. Z. Carter et al. BLOOD
- Wnt signaling and stem cell control
- (2008) Roel Nusse CELL RESEARCH
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