Herbal compound triptolide synergistically enhanced antitumor activity of amino-terminal fragment of urokinase

The combination of bendamustine, bortezomib, and rituximab for patients with relapsed/refractory indolent and mantle cell non-Hodgkin lymphoma

(2011) J. W. Friedberg et al.   BLOOD

Plasminogen Activator uPA Is a Direct Transcriptional Target of the JAG1-Notch Receptor Signaling Pathway in Breast Cancer

(2011) M. Shimizu et al.   CANCER RESEARCH

Triptolide and its expanding multiple pharmacological functions

(2011) Qiuyan Liu   INTERNATIONAL IMMUNOPHARMACOLOGY

Synthesis and biological evaluation of novel triptolide analogues for anticancer activity

(2010) Bing Zhou et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Triptolide simultaneously induces reactive oxygen species, inhibits NF-κB activity and sensitizes 5-fluorouracil in colorectal cancer cell lines

(2009) Bing Xu et al.   CANCER LETTERS

Phase I dose-escalation study of F60008, a novel apoptosis inducer, in patients with advanced solid tumours

(2009) J.J.E.M. Kitzen et al.   EUROPEAN JOURNAL OF CANCER

Triptolide-induced suppression of phospholipase D expression inhibits proliferation of MDA-MB-231 breast cancer cells

(2009) Dong Woo Kang et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

RNAi targeting urokinase-type plasminogen activator receptor inhibits metastasis and progression of oral squamous cell carcinomain vivo

(2009) Hao Zhou et al.   INTERNATIONAL JOURNAL OF CANCER

A Small-Molecule Triptolide Suppresses Angiogenesis and Invasion of Human Anaplastic Thyroid Carcinoma Cells via Down-Regulation of the Nuclear Factor- B Pathway

(2009) W. Zhu et al.   MOLECULAR PHARMACOLOGY

Triptolide alters histone H3K9 and H3K27 methylation state and induces G0/G1 arrest and caspase-dependent apoptosis in multiple myeloma in vitro

(2009) Fei Zhao et al.   TOXICOLOGY

Effects of cytochrome P4503A inducer dexamethasone on the metabolism and toxicity of triptolide in rat

(2009) Xiaochuan Ye et al.   TOXICOLOGY LETTERS

Akt-dependent regulation of NF- B is controlled by mTOR and Raptor in association with IKK

(2008) H. C. Dan et al.   GENES & DEVELOPMENT

JNK signaling in apoptosis

(2008) D N Dhanasekaran et al.   ONCOGENE

Cross-talk between the Akt and NF-κB Signaling Pathways Inhibits MEHP-Induced Germ Cell Apoptosis

(2008) Rachel Rogers et al.   TOXICOLOGICAL SCIENCES