(R)-α-trifluoromethylalanine containing short peptide in the inhibition of amyloid peptide fibrillation

Impact of fluorination on proteolytic stability of peptides: a case study with α-chymotrypsin and pepsin

(2014) Vivian Asante et al.   AMINO ACIDS

Potent γ-secretase inhibitors/modulators interact with amyloid-β fibrils but do not inhibit fibrillation: A high-resolution NMR study

(2014) Ravichandran Yesuvadian et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structure–activity relationships of sugar-based peptidomimetics as modulators of amyloid β-peptide early oligomerization and fibrillization

(2014) Julia Kaffy et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Fluorinated beta-sheet breaker peptides

(2014) Joana A. Loureiro et al.   Journal of Materials Chemistry B

Resolution of Oligomeric Species during the Aggregation of Aβ1–40 Using 19F NMR

(2013) Yuta Suzuki et al.   BIOCHEMISTRY

Evaluation of membrane models and their composition for islet amyloid polypeptide-membrane aggregation

(2013) Lucie Caillon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

A small molecule that displays marked reactivity toward copper– versus zinc–amyloid-β implicated in Alzheimer's disease

(2013) Masha G. Savelieff et al.   CHEMICAL COMMUNICATIONS

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

(2013) Jiang Wang et al.   CHEMICAL REVIEWS

Synthesis of an MIF-1 analogue containing enantiopure ( S )-α-trifluoromethyl-proline and biological evaluation on nociception

(2013) Ibtissem Jlalia et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Fluorinated amino acids in amyloid formation: a symphony of size, hydrophobicity and α-helix propensity

(2013) Ulla I. M. Gerling et al.   Chemical Science

Alternative Pathways of Human Islet Amyloid Polypeptide Aggregation Distinguished by 19F Nuclear Magnetic Resonance-Detected Kinetics of Monomer Consumption

(2012) Yuta Suzuki et al.   BIOCHEMISTRY

Structure-Activity Relationships of Organofluorine Inhibitors of β-Amyloid Self-Assembly

(2012) Béla Török et al.   ChemMedChem

Fluorine local environment: from screening to drug design

(2012) Anna Vulpetti et al.   DRUG DISCOVERY TODAY

Local Control of the Cis–Trans Isomerization and Backbone Dihedral Angles in Peptides Using Trifluoromethylated Pseudoprolines

(2012) Debby Feytens et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Inhibition of Amyloid Peptide Fibrillation by Inorganic Nanoparticles: Functional Similarities with Proteins

(2011) Seong Il Yoo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A partially folded structure of amyloid-beta(1–40) in an aqueous environment

(2011) Subramanian Vivekanandan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Fluorinated amino acids: compatibility with native protein structures and effects on protein–protein interactions

(2011) Mario Salwiczek et al.   CHEMICAL SOCIETY REVIEWS

Sugar-based peptidomimetics inhibit amyloid β-peptide aggregation

(2011) Bertrand Dorgeret et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Aromatic Small Molecules Remodel Toxic Soluble Oligomers of Amyloid β through Three Independent Pathways

(2010) Ali Reza A. Ladiwala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aβ42 Neurotoxicity Is Mediated by Ongoing Nucleated Polymerization Process Rather than by Discrete Aβ42 Species

(2010) Asad Jan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Characterization of a Soluble Amyloid β-Peptide Oligomer

(2009) Liping Yu et al.   BIOCHEMISTRY

Convenient Synthesis ofN-Terminal Tfm-Dipeptides from Unprotected Enantiopure α-Tfm-Proline and α-Tfm-Alanine

(2009) Grégory Chaume et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Cognitive-Performance Recovery of Alzheimer's Disease Model Mice by Modulation of Early Soluble Amyloidal Assemblies

(2008) Anat Frydman-Marom et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iodocyclization of Chiral CF3-Allylmorpholinones: A Versatile Strategy for the Synthesis of Enantiopure α-Tfm-Prolines and α-Tfm-Dihydroxyprolines

(2008) Caroline Caupène et al.   ORGANIC LETTERS

Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane

(2008) M. F. M. Engel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA