Properdin: A Novel Target for Neuroprotection in Neonatal Hypoxic-Ischemic Brain Injury

Mesenchymal Stromal Cell Derived Extracellular Vesicles Reduce Hypoxia-Ischaemia Induced Perinatal Brain Injury

(2019) Claudia Sisa et al.   Frontiers in Physiology

Hypothermia Is Neuroprotective after Severe Hypoxic-Ischaemic Brain Injury in Neonatal Rats Pre-Exposed to PAM3CSK4

(2018) Mari Falck et al.   DEVELOPMENTAL NEUROSCIENCE

Human Properdin Modulates Macrophage: Mycobacterium bovis BCG Interaction via Thrombospondin Repeats 4 and 5

(2018) Maha Ahmed Al-Mozaini et al.   Frontiers in Immunology

Perinatal Hypoxia and Ischemia in Animal Models of Schizophrenia

(2018) Dimitri Hefter et al.   Frontiers in Psychiatry

Intranasal C3a treatment ameliorates cognitive impairment in a mouse model of neonatal hypoxic–ischemic brain injury

(2017) Javier Morán et al.   EXPERIMENTAL NEUROLOGY

Inhibition of Signal Transducer and Activator of Transcription 3 (STAT3) reduces neonatal hypoxic-ischaemic brain damage

(2016) Mariya Hristova et al.   JOURNAL OF NEUROCHEMISTRY

Plasticity in the Neonatal Brain following Hypoxic-Ischaemic Injury

(2016) Eridan Rocha-Ferreira et al.   NEURAL PLASTICITY

Modulation of post-stroke degenerative and regenerative processes and subacute protection by site-targeted inhibition of the alternative pathway of complement

(2015) Ali Alawieh et al.   Journal of Neuroinflammation

The role of different strain backgrounds in bacterial endotoxin-mediated sensitization to neonatal hypoxic–ischemic brain damage

(2015) E. Rocha-Ferreira et al.   NEUROSCIENCE

Antimicrobial Peptides and Complement in Neonatal Hypoxia-Ischemia Induced Brain Damage

(2015) Eridan Rocha-Ferreira et al.   Frontiers in Immunology

Properdin Deficiency in Murine Models of Nonseptic Shock

(2014) N. D. Ivanovska et al.   JOURNAL OF IMMUNOLOGY

Properdin Plays a Protective Role in Polymicrobial Septic Peritonitis

(2014) C. M. Stover et al.   JOURNAL OF IMMUNOLOGY

Peptidylarginine deiminases: novel drug targets for prevention of neuronal damage following hypoxic ischemic insult (HI) in neonates

(2014) Sigrun Lange et al.   JOURNAL OF NEUROCHEMISTRY

Inflammatory responses in hypoxic ischemic encephalopathy

(2013) Fudong Liu et al.   ACTA PHARMACOLOGICA SINICA

Behavioral and histological outcomes following neonatal HI injury in a preterm (P3) and term (P7) rodent model

(2013) M. Alexander et al.   BEHAVIOURAL BRAIN RESEARCH

Brain Hypothermic Therapy Dramatically Decreases Elevated Blood Concentrations of High Mobility Group Box 1 in Neonates with Hypoxic-Ischemic Encephalopathy

(2013) Toshihiko Nakamura et al.   DISEASE MARKERS

Blocking Properdin, the Alternative Pathway, and Anaphylatoxin Receptors Ameliorates Renal Ischemia-Reperfusion Injury in Decay-Accelerating Factor and CD59 Double-Knockout Mice

(2013) T. Miwa et al.   JOURNAL OF IMMUNOLOGY

Biomarkers for Severity of Neonatal Hypoxic-Ischemic Encephalopathy and Outcomes in Newborns Receiving Hypothermia Therapy

(2013) Lina F. Chalak et al.   JOURNAL OF PEDIATRICS

Properdin in complement activation and tissue injury

(2013) Allison M. Lesher et al.   MOLECULAR IMMUNOLOGY

Hypothermia is not neuroprotective after infection-sensitized neonatal hypoxic–ischemic brain injury

(2013) Damjan Osredkar et al.   RESUSCITATION

Distribution of pH Changes in Mouse Neonatal Hypoxic-Ischaemic Insult

(2012) Giles S. Kendall et al.   DEVELOPMENTAL NEUROSCIENCE

The Alternative Complement Pathway Propagates Inflammation and Injury in Murine Ischemic Stroke

(2012) Andrew Elvington et al.   JOURNAL OF IMMUNOLOGY

Implementation and Conduct of Therapeutic Hypothermia for Perinatal Asphyxial Encephalopathy in the UK – Analysis of National Data

(2012) Denis Azzopardi et al.   PLoS One

Predicting motor outcome and death in term hypoxic-ischemic encephalopathy

(2011) M. Martinez-Biarge et al.   NEUROLOGY

Placental pathology in asphyxiated newborns meeting the criteria for therapeutic hypothermia

(2010) Pia Wintermark et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

When and Why Do Brain Cells Die?

(2010) Peter D. Gluckman et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Epidemiology of neonatal encephalopathy and hypoxic–ischaemic encephalopathy

(2010) Jennifer J. Kurinczuk et al.   EARLY HUMAN DEVELOPMENT

Perinatal Hypoxic-Ischemic Encephalopathy

(2010) Ming-Chi Lai et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Genetic and therapeutic targeting of properdin in mice prevents complement-mediated tissue injury

(2010) Yuko Kimura et al.   JOURNAL OF CLINICAL INVESTIGATION

TGFß1 Stimulates the Over-Production of White Matter Astrocytes from Precursors of the “Brain Marrow” in a Rodent Model of Neonatal Encephalopathy

(2010) Jennifer M. Bain et al.   PLoS One

Activation and deactivation of periventricular white matter phagocytes during postnatal mouse development

(2009) Mariya Hristova et al.   GLIA

Lipopolysaccharide Sensitizes Neonatal Hypoxic-Ischemic Brain Injury in a MyD88-Dependent Manner

(2009) X. Wang et al.   JOURNAL OF IMMUNOLOGY

Sex Differences in a Hypoxia Model of Preterm Brain Damage

(2009) Sonia R Mayoral et al.   PEDIATRIC RESEARCH

Activator-specific requirement of properdin in the initiation and amplification of the alternative pathway complement

(2007) Y. Kimura et al.   BLOOD