Modulation of post-stroke degenerative and regenerative processes and subacute protection by site-targeted inhibition of the alternative pathway of complement

Complement in the Homeostatic and Ischemic Brain

(2015) Ali Alawieh et al.   Frontiers in Immunology

A Novel Targeted Inhibitor of the Alternative Pathway of Complement and Its Therapeutic Application in Ischemia/Reperfusion Injury

(2014) Y. Huang et al.   JOURNAL OF IMMUNOLOGY

Receptor for complement peptide C3a: a therapeutic target for neonatal hypoxic-ischemic brain injury

(2013) Katarina Järlestedt et al.   FASEB JOURNAL

Targeting Mannose-Binding Lectin Confers Long-Lasting Protection With a Surprisingly Wide Therapeutic Window in Cerebral Ischemia

(2012) Franca Orsini et al.   CIRCULATION

The complement system in ischemia–reperfusion injuries

(2012) William B. Gorsuch et al.   IMMUNOBIOLOGY

The Alternative Complement Pathway Propagates Inflammation and Injury in Murine Ischemic Stroke

(2012) Andrew Elvington et al.   JOURNAL OF IMMUNOLOGY

Complement activation in the injured central nervous system: another dual-edged sword?

(2012) Faith H Brennan et al.   Journal of Neuroinflammation

Complement Inhibition Promotes Endogenous Neurogenesis and Sustained Anti-Inflammatory Neuroprotection following Reperfused Stroke

(2012) Andrew F. Ducruet et al.   PLoS One

Activation and Control of CNS Innate Immune Responses in Health and Diseases: A Balancing Act Finely Tuned by Neuroimmune Regulators (NIReg)

(2011) Jean-Jacques Hoarau et al.   CNS & Neurological Disorders-Drug Targets

The Contribution of Mannose Binding Lectin to Reperfusion Injury after Ischemic Stroke

(2011) Helena Morrison et al.   CURRENT NEUROVASCULAR RESEARCH

Developmental dysregulation of adult neurogenesis

(2011) H. Georg Kuhn et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Complement Receptor 2 Is Expressed in Neural Progenitor Cells and Regulates Adult Hippocampal Neurogenesis

(2011) M. Moriyama et al.   JOURNAL OF NEUROSCIENCE

The Neuroprotective Effect of Genetic Mannose-Binding Lectin Deficiency Is Not Sustained in the Subacute Phase of Stroke

(2011) Andrew F. Ducruet et al.   Translational Stroke Research

Review: Soluble innate immune pattern-recognition proteins for clearing dying cells and cellular components: implications on exacerbating or resolving inflammation

(2010) Michael L. Litvack et al.   Innate Immunity

Complement Component C1q Mediates Mitochondria-Driven Oxidative Stress in Neonatal Hypoxic-Ischemic Brain Injury

(2010) V. S. Ten et al.   JOURNAL OF NEUROSCIENCE

Genetically-Defined Deficiency of Mannose-Binding Lectin Is Associated with Protection after Experimental Stroke in Mice and Outcome in Human Stroke

(2010) Alvaro Cervera et al.   PLoS One

Recombinant C1 inhibitor in brain ischemic injury

(2009) Raffaella Gesuete et al.   ANNALS OF NEUROLOGY

Complement-Derived Anaphylatoxin C3a Regulates In Vitro Differentiation and Migration of Neural Progenitor Cells

(2009) Noriko Shinjyo et al.   STEM CELLS

Evaluation of spatial memory of C57BL/6J and CD1 mice in the Barnes maze, the Multiple T-maze and in the Morris water maze

(2008) Sudarshan S. Patil et al.   BEHAVIOURAL BRAIN RESEARCH

Complement anaphylatoxin C5a neuroprotects through regulation of glutamate receptor subunit 2 in vitro and in vivo

(2008) Piali Mukherjee et al.   Journal of Neuroinflammation

Direct multiplexed measurement of gene expression with color-coded probe pairs

(2008) Gary K Geiss et al.   NATURE BIOTECHNOLOGY