Cyclopropanation of Fluorinated Sulfur Ylides with 1‐Azadienes: Facile Synthesis of CF 3 ‐Substituted Spiro Scaffolds
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Title
Cyclopropanation of Fluorinated Sulfur Ylides with 1‐Azadienes: Facile Synthesis of CF
3
‐Substituted Spiro Scaffolds
Authors
Keywords
-
Journal
Asian Journal of Organic Chemistry
Volume 8, Issue 12, Pages 2175-2179
Publisher
Wiley
Online
2019-11-06
DOI
10.1002/ajoc.201900651
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Note: Only part of the references are listed.- [4 + 1 + 1] Annulations of α-Bromo Carbonyls and 1-Azadienes toward Fused Benzoazaheterocycles
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- Advances in spirocyclic hybrids: chemistry and medicinal actions
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- Corey–Chaykovsky Reactions of Nitro Styrenes Enable cis-Configured Trifluoromethyl Cyclopropanes
- (2017) Katharina J. Hock et al. JOURNAL OF ORGANIC CHEMISTRY
- Nine-Membered Benzofuran-Fused Heterocycles: Enantioselective Synthesis by Pd-Catalysis and Rearrangement via Transannular Bond Formation
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- Fluorine in medicinal chemistry
- (2007) Sophie Purser et al. CHEMICAL SOCIETY REVIEWS
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