In Vitro Thrombogenicity Testing of Biomaterials

BloodSurf 2017: News from the Blood-Biomaterial Frontier

(2019) Irini Sotiri et al.   Acta Biomaterialia

Unraveling the Mechanobiology of the Immune System

(2019) Jeong-Ki Kim et al.   Advanced Healthcare Materials

Three-dimensional extent of flow stagnation in transcatheter heart valves

(2019) Vrishank Raghav et al.   Journal of the Royal Society Interface

Sterilization of implantable polymer-based medical devices: A review

(2018) Namita P. Tipnis et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Tissue Engineering at the Blood-Contacting Surface: A Review of Challenges and Strategies in Vascular Graft Development

(2018) Daniel Radke et al.   Advanced Healthcare Materials

Blood damage in Left Ventricular Assist Devices: Pump thrombosis or system thrombosis?

(2018) Matteo Selmi et al.   INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS

Genotoxicity testing: progress and prospects for the next decade

(2017) Hasan Turkez et al.   Expert Opinion on Drug Metabolism & Toxicology

Platelet Aggregometry Testing: Molecular Mechanisms, Techniques and Clinical Implications

(2017) Katalin Koltai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neutrophil-mediated vascular barrier injury: Role of neutrophil extracellular traps

(2017) Jamie E. Meegan et al.   MICROCIRCULATION

Biocompatibility assessment of silk nanoparticles: hemocompatibility and internalization by human blood cells

(2017) Manfred F. Maitz et al.   Nanomedicine-Nanotechnology Biology and Medicine

Cardiovascular disease in haemodialysis: role of the intravascular innate immune system

(2017) Kristina N. Ekdahl et al.   Nature Reviews Nephrology

Interaction of endothelial cells with macrophages—linking molecular and metabolic signaling

(2017) Joanna Kalucka et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Surface dependent contact activation of factor XII and blood plasma coagulation induced by mixed thiol surfaces

(2017) James W. Bauer et al.   Biointerphases

Application of advanced sampling and analysis methods to predict the structure of adsorbed protein on a material surface

(2017) Tigran M. Abramyan et al.   Biointerphases

Absence of conformational change in complement factor 3 and factor XII adsorbed to acrylate polymers is related to a high degree of polymer backbone flexibility

(2017) Karin Fromell et al.   Biointerphases

Response to “Correspondence Concerning Hemocompatibility of Superhemophobic Titania Surfaces”

(2017) S. Movafaghi et al.   Advanced Healthcare Materials

Comment on: “Hemocompatibility of Superhemophobic Titania Surfaces”

(2017) Steffen Braune et al.   Advanced Healthcare Materials

Neutrophil extracellular trap formation upon exposure of hydrophobic materials to human whole blood causes thrombogenic reactions

(2017) Claudia Sperling et al.   Biomaterials Science

In vitro blood flow model with physiological wall shear stress for hemocompatibility testing—An example of coronary stent testing

(2016) Gerwin Erik Engels et al.   Biointerphases

Thrombogenicity and hemocompatibility of biomaterials

(2016) Friedrich Jung et al.   Biointerphases

Role of flow for the deposition of platelets

(2016) Klaus Affeld et al.   Biointerphases

Platelets and coronary artery disease: Interactions with the blood vessel wall and cardiovascular devices

(2016) Markus Reinthaler et al.   Biointerphases

In vitro hemocompatibility testing: The importance of fresh blood

(2016) Sjoerd Leendert Johannes Blok et al.   Biointerphases

Acquired von Willebrand syndrome associated with left ventricular assist device

(2016) A. Nascimbene et al.   BLOOD

Emerging anticoagulant strategies

(2016) James C. Fredenburgh et al.   BLOOD

Trend to move from permanent metals to degradable, multifunctional polymer or metallic implants in the example of coronary stents

(2016) Markus Reinthaler et al.   Expert Review of Medical Devices

The pathology of the foreign body reaction against biomaterials

(2016) R. Klopfleisch et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Platelet Interaction with Innate Immune Cells

(2016) Julia Barbara Kral et al.   TRANSFUSION MEDICINE AND HEMOTHERAPY

In vitro blood flow model with physiological wall shear stress for hemocompatibility testing—An example of coronary stent testing

(2016) Gerwin Erik Engels et al.   Biointerphases

Thrombogenicity and hemocompatibility of biomaterials

(2016) Friedrich Jung et al.   Biointerphases

Role of flow for the deposition of platelets

(2016) Klaus Affeld et al.   Biointerphases

Platelets and coronary artery disease: Interactions with the blood vessel wall and cardiovascular devices

(2016) Markus Reinthaler et al.   Biointerphases

In vitro hemocompatibility testing: The importance of fresh blood

(2016) Sjoerd Leendert Johannes Blok et al.   Biointerphases

Hemocompatibility of Superhemophobic Titania Surfaces

(2016) Sanli Movafaghi et al.   Advanced Healthcare Materials

Experimental characterization of adsorbed protein orientation, conformation, and bioactivity

(2015) Aby A. Thyparambil et al.   Biointerphases

Prediction of inflammatory responses induced by biomaterials in contact with human blood using protein fingerprint from plasma

(2015) Anna E. Engberg et al.   BIOMATERIALS

Venous stasis and whole blood platelet aggregometry

(2015) Gabriel Lima-Oliveira et al.   BLOOD COAGULATION & FIBRINOLYSIS

Diet and haemostasis — A comprehensive overview

(2015) Marlien Pieters et al.   BLOOD REVIEWS

Cell-based detection of microbial biomaterial contaminations

(2015) Toralf Roch et al.   CLINICAL HEMORHEOLOGY AND MICROCIRCULATION

Quantification of adherent platelets on polymer-based biomaterials. Comparison of colorimetric and microscopic assessment

(2015) S. Braune et al.   CLINICAL HEMORHEOLOGY AND MICROCIRCULATION

Neoatherosclerosis: overview of histopathologic findings and implications for intravascular imaging assessment

(2015) Fumiyuki Otsuka et al.   EUROPEAN HEART JOURNAL

Laboratory testing for platelet function disorders

(2015) S. J. Israels   International Journal of Laboratory Hematology

Adhesion and activation of platelets from subjects with coronary artery disease and apparently healthy individuals on biomaterials

(2015) S. Braune et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Medical device-induced thrombosis: what causes it and how can we prevent it?

(2015) I. H. Jaffer et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet adhesion, aggregation, and embolism on artificial surfaces in non-parallel blood flow

(2015) Thorsten Kragh et al.   Microfluidics and Nanofluidics

Heparin-Induced Thrombocytopenia

(2015) Andreas Greinacher   NEW ENGLAND JOURNAL OF MEDICINE

The Effect of Ginger (Zingiber officinale) on Platelet Aggregation: A Systematic Literature Review

(2015) Wolfgang Marx et al.   PLoS One

The Effect of Omega-3 Polyunsaturated Fatty Acids on Fibrin and Thrombin Generation in Healthy Subjects and Subjects with Cardiovascular Disease

(2015) Bradley McEwen et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Experimental characterization of adsorbed protein orientation, conformation, and bioactivity

(2015) Aby A. Thyparambil et al.   Biointerphases

Platelets and Infections – Complex Interactions with Bacteria

(2015) Hind Hamzeh-Cognasse et al.   Frontiers in Immunology

Technical-Induced Hemolysis in Patients with Respiratory Failure Supported with Veno-Venous ECMO – Prevalence and Risk Factors

(2015) Karla Lehle et al.   PLoS One

Preclinical Evaluation of the Thrombogenicity and Endothelialization of Bare Metal and Surface-Coated Neurovascular Stents

(2014) S. Krajewski et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Dynamic in vitro hemocompatibility testing – improving the signal to noise ratio

(2014) M. Mueller et al.   Biomedical Engineering-Biomedizinische Technik

Proteins, platelets, and blood coagulation at biomaterial interfaces

(2014) Li-Chong Xu et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Optimal anticoagulation duration of unfractionated and low molecular weight heparin in non-ST elevation acute coronary syndrome: A systematic review of the literature

(2014) Irbaz Bin Riaz et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Shear-Stress-Induced Conformational Changes of von Willebrand Factor in a Water–Glycerol Mixture Observed with Single Molecule Microscopy

(2014) Robrecht M. A. Vergauwe et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Hemocompatibility testing according to ISO 10993-4: Discrimination between pyrogen- and device-induced hemostatic activation

(2014) Katharina Stang et al.   Materials Science & Engineering C-Materials for Biological Applications

Platelet adhesion changes during storage studied with a novel method using flow cytometry and protein-coated beads

(2014) Nahreen Tynngård et al.   PLATELETS

Neutrophils scan for activated platelets to initiate inflammation

(2014) Vinatha Sreeramkumar et al.   SCIENCE

The Influence of Diet and Nutrients on Platelet Function

(2014) Bradley McEwen   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Effects of storage time and temperature on coagulation tests and factors in fresh plasma

(2014) Limin Feng et al.   Scientific Reports

Decreased tissue factor expression with increased CD11b upregulation on elastin-based biomaterial coatings

(2014) M. K. Rooney et al.   Biomaterials Science

Blood compatible materials: state of the art

(2014) Xiaoli Liu et al.   Journal of Materials Chemistry B

In Vitro Shear Stress-Induced Platelet Activation: Sensitivity of Human and Bovine Blood

(2013) Qijin Lu et al.   ARTIFICIAL ORGANS

Effect of Air Exposure and Suction on Blood Cell Activation and Hemolysis in an In Vitro Cardiotomy Suction Model

(2013) Ahmed M. El-Sabbagh et al.   ASAIO JOURNAL

Are there sufficient standards for the in vitro hemocompatibility testing of biomaterials?

(2013) Steffen Braune et al.   Biointerphases

A review of adaptive mechanisms in cell responses towards oxidative stress caused by dental resin monomers

(2013) Stephanie Krifka et al.   BIOMATERIALS

Von Willlebrand Adhesion to Surfaces at High Shear Rates Is Controlled by Long-Lived Bonds

(2013) Charles E. Sing et al.   BIOPHYSICAL JOURNAL

Hierarchical organization in the hemostatic response and its relationship to the platelet-signaling network

(2013) T. J. Stalker et al.   BLOOD

Inhibition of biomaterial-induced complement activation attenuates the inflammatory host response to implantation

(2013) Ioannis Kourtzelis et al.   FASEB JOURNAL

Recommendations for the standardization of light transmission aggregometry: a consensus of the working party from the platelet physiology subcommittee of SSC/ISTH

(2013) M. Cattaneo et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Mechanisms of hemolysis-associated platelet activation

(2013) C. C. Helms et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The physiological and pathophysiological roles of platelet CLEC-2

(2013) Stacey A. Langan et al.   THROMBOSIS AND HAEMOSTASIS

State of the Art in Platelet Function Testing

(2013) Beate E. Kehrel et al.   TRANSFUSION MEDICINE AND HEMOTHERAPY

The Vroman effect: Competitive protein exchange with dynamic multilayer protein aggregates

(2012) Stacey L. Hirsh et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Comparison of HemoCue® hemoglobin-meter and automated hematology analyzer in measurement of hemoglobin levels in pregnant women at Khartoum hospital, Sudan

(2012) Ishag Adam et al.   Diagnostic Pathology

Guidelines on the laboratory aspects of assays used in haemostasis and thrombosis

(2012) I. Mackie et al.   International Journal of Laboratory Hematology

The effect of shear on in vitro platelet and leukocyte material-induced activation

(2012) Xiaojian Chang et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Numerical and experimental evaluation of platelet deposition to collagen coated surface at low shear rates

(2012) Klaus Affeld et al.   JOURNAL OF BIOMECHANICS

Platelet-targeting sensor reveals thrombin gradients within blood clots forming in microfluidic assays and in mouse

(2012) J. D. WELSH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Time-of-Flight Secondary Ion Mass Spectrometry with Principal Component Analysis of Titania–Blood Plasma Interfaces

(2012) Ricardo Tejero et al.   LANGMUIR

Quality Standards for Sample Collection in Coagulation Testing

(2012) Giuseppe Lippi et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Red blood cell-derived microparticles isolated from blood units initiate and propagate thrombin generation

(2012) Olivier Rubin et al.   TRANSFUSION

Novel Biopolymers to Enhance Endothelialisation of Intra-vascular Devices

(2012) Salvatore Pernagallo et al.   Advanced Healthcare Materials

Understanding protein adsorption phenomena at solid surfaces

(2011) Michael Rabe et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

Evidence of Platelet Activation at Medically Used Hypothermia and Mechanistic Data Indicating ADP as a Key Mediator and Therapeutic Target

(2011) Andreas Straub et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The effect of upstream platelet–fibrinogen interactions on downstream adhesion and activation

(2011) Lindsey E. Corum et al.   BIOMATERIALS

Protein adsorption in three dimensions

(2011) Erwin A. Vogler   BIOMATERIALS

Platelet activation by heparin

(2011) A. Greinacher   BLOOD

Heparin promotes platelet responsiveness by potentiating  IIb 3-mediated outside-in signaling

(2011) C. Gao et al.   BLOOD

A novel in vitro model for preclinical testing of the hemocompatibility of intravascular stents according to ISO 10993-4

(2011) Stefan Sinn et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Time-Dependent Conformational Changes in Adsorbed Albumin and Its Effect on Platelet Adhesion

(2011) Balakrishnan Sivaraman et al.   LANGMUIR

Degradable, Multifunctional Cardiovascular Implants: Challenges and Hurdles

(2011) Friedrich Jung et al.   MRS BULLETIN

Heparin modulates the conformation and signaling of platelet integrin αIIbβ3

(2011) Mayumi Yagi et al.   THROMBOSIS RESEARCH

Collection of Blood Specimens by Venipuncture for Plasma-Based Coagulation Assays

(2010) Maarten T.M. Raijmakers et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Signaling During Platelet Adhesion and Activation

(2010) Zhenyu Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The immobilization of recombinant human tropoelastin on metals using a plasma-activated coating to improve the biocompatibility of coronary stents

(2010) Anna Waterhouse et al.   BIOMATERIALS

Complement anaphylatoxin C5a contributes to hemodialysis-associated thrombosis

(2010) I. Kourtzelis et al.   BLOOD

Discard tubes are not necessary when drawing samples for specialized coagulation testing

(2010) Kristi J Smock et al.   BLOOD COAGULATION & FIBRINOLYSIS

Contemporary platelet function testing

(2010) Emmanuel J. Favaloro et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Porcine platelets in vitro and in vivo studies: Relevance to human thrombosis research

(2010) Eirik Søfteland et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Cytocompatibility testing of cell culture modules fabricated from specific candidate biomaterials using injection molding

(2010) Bernhard Hiebl et al.   JOURNAL OF BIOTECHNOLOGY

Complement Component C3 Binds to Activated Normal Platelets without Preceding Proteolytic Activation and Promotes Binding to Complement Receptor 1

(2010) Osama A. Hamad et al.   JOURNAL OF IMMUNOLOGY

Hydrophilic polymer emboli: an under-recognized iatrogenic cause of ischemia and infarct

(2010) Rupal I Mehta et al.   MODERN PATHOLOGY

A novel nanocomposite polymer for development of synthetic heart valve leaflets

(2009) Asmeret G. Kidane et al.   Acta Biomaterialia

The Relationships Between Air Exposure, Negative Pressure, and Hemolysis

(2009) Joshua R. Pohlmann et al.   ASAIO JOURNAL

Inhibition of complement activation on a model biomaterial surface by streptococcal M protein-derived peptides

(2009) Anna E. Engberg et al.   BIOMATERIALS

Immunocompatibility properties of lipid–polymer hybrid nanoparticles with heterogeneous surface functional groups

(2009) Carolina Salvador-Morales et al.   BIOMATERIALS

Contact activation of blood-plasma coagulation

(2009) Erwin A. Vogler et al.   BIOMATERIALS

Surface-energy dependent contact activation of blood factor XII

(2009) Avantika Golas et al.   BIOMATERIALS

The Adherence of platelets to adsorbed albumin by receptor-mediated recognition of binding sites exposed by adsorption-induced unfolding

(2009) Balakrishnan Sivaraman et al.   BIOMATERIALS

The relationship between platelet adhesion on surfaces and the structure versus the amount of adsorbed fibrinogen

(2009) Balakrishnan Sivaraman et al.   BIOMATERIALS

Standardization of incubation conditions for hemolysis testing of biomaterials

(2009) Sandra Henkelman et al.   Materials Science & Engineering C-Materials for Biological Applications

A shear gradient–dependent platelet aggregation mechanism drives thrombus formation

(2009) Warwick S Nesbitt et al.   NATURE MEDICINE

The effect of ex vivo anticoagulants on whole blood platelet aggregation

(2009) Madeleine L. Kalb et al.   PLATELETS

Mechanoenzymatic Cleavage of the Ultralarge Vascular Protein von Willebrand Factor

(2009) X. Zhang et al.   SCIENCE

Biological Influence of Physical Exercise on Hemostasis

(2009) Giuseppe Lippi et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Novel and unexpected clearance mechanisms for cold platelets

(2009) Viktoria Rumjantseva et al.   TRANSFUSION AND APHERESIS SCIENCE

Soluble, platelet-bound, and total P-selectin as indices of platelet activation in congestive heart failure

(2008) Irene Chung et al.   ANNALS OF MEDICINE

Blood compatibility of surfaces with superlow protein adsorption

(2008) Zheng Zhang et al.   BIOMATERIALS

Surface Chemistry Influences Implant Biocompatibility

(2008) Liping Tang et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Contributions of contact activation pathways of coagulation factor XII in plasma

(2008) Kaushik Chatterjee et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Hirudin versus heparin for use in whole bloodin vitrobiocompatibility models

(2008) Fredrik Bexborn et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Vanadate-Induced Suicidal Erythrocyte Death

(2008) Michael Föller et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Foreign body reaction to biomaterials

(2008) James M. Anderson et al.   SEMINARS IN IMMUNOLOGY

Platelet anaesthesia during extracorporeal circulation: Differential effects of GP IIb/IIIa blockers on platelet activation marker P-selectin expression at hypothermia

(2008) Andreas Straub et al.   THROMBOSIS RESEARCH