Extracellular vesicles derived from human Wharton’s jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Extracellular vesicles derived from human Wharton’s jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers
Authors
Keywords
-
Journal
Stem Cell Research & Therapy
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-11-20
DOI
10.1186/s13287-019-1432-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Secretome of Mesenchymal Stem Cells and Its Potential Protective Effects on Brain Pathologies
- (2019) Eliana Baez-Jurado et al. MOLECULAR NEUROBIOLOGY
- Secretome of adipose-derived mesenchymal stem cells promotes skeletal muscle regeneration through synergistic action of extracellular vesicle cargo and soluble proteins
- (2019) Robert Mitchell et al. Stem Cell Research & Therapy
- Exosomes derived from hypoxia-preconditioned mesenchymal stromal cells ameliorate cognitive decline by rescuing synaptic dysfunction and regulating inflammatory responses in APP/PS1 mice
- (2018) Guo-Hong Cui et al. FASEB JOURNAL
- The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimer's disease
- (2018) Andre F Batista et al. JOURNAL OF PATHOLOGY
- Dysregulation of Mesenchymal Stromal Cell Antioxidant Responses in Progressive Multiple Sclerosis
- (2018) Juliana Redondo et al. Stem Cells Translational Medicine
- Human Wharton’s jelly mesenchymal stem cells protect axotomized rat retinal ganglion cells via secretion of anti-inflammatory and neurotrophic factors
- (2018) Jose E. Millán-Rivero et al. Scientific Reports
- Mesenchymal Stromal Cell Secretome: Influencing Therapeutic Potential by Cellular Pre-conditioning
- (2018) Joana R. Ferreira et al. Frontiers in Immunology
- Mesenchymal stem cell-derived extracellular vesicles: a glimmer of hope in treating Alzheimer’s disease
- (2017) Lee Chuen Liew et al. INTERNATIONAL IMMUNOLOGY
- Mesenchymal Stem/Stromal Cell-Derived Extracellular Vesicles and Their Potential as Novel Immunomodulatory Therapeutic Agents
- (2017) Verena Börger et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine
- (2017) Francisco Vizoso et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice
- (2017) Jordano Brito-Moreira et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mesenchymal stem cells and cell-derived extracellular vesicles protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers
- (2017) Mariana A. de Godoy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mesenchymal stem/stromal cell extracellular vesicles: From active principle to next generation drug delivery system
- (2017) Barbara Crivelli et al. JOURNAL OF CONTROLLED RELEASE
- Astrocyte Transforming Growth Factor Beta 1 Protects Synapses against Aβ Oligomers in Alzheimer's Disease Model
- (2017) Luan Pereira Diniz et al. JOURNAL OF NEUROSCIENCE
- Astrocyte dysfunction in Alzheimer disease
- (2017) Crystal Acosta et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Neurotoxic reactive astrocytes are induced by activated microglia
- (2017) Shane A. Liddelow et al. NATURE
- Administrations of human adult ischemia-tolerant mesenchymal stem cells and factors reduce amyloid beta pathology in a mouse model of Alzheimer's disease
- (2017) Taoufiq Harach et al. NEUROBIOLOGY OF AGING
- Comparative phenotypic transcriptional characterization of human full-term placenta-derived mesenchymal stromal cells compared to bone marrow-derived mesenchymal stromal cells after differentiation in myogenic medium
- (2017) Melanie L. Hart et al. PLACENTA
- Concise Review: Mesenchymal Stem Cells in Neurodegenerative Diseases
- (2017) Rotem Volkman et al. STEM CELLS
- Non-coding RNAs in Mesenchymal Stem Cell-Derived Extracellular Vesicles: Deciphering Regulatory Roles in Stem Cell Potency, Inflammatory Resolve, and Tissue Regeneration
- (2017) Farah Fatima et al. Frontiers in Genetics
- Reactive Oxygen Species: Stuck in the Middle of Neurodegeneration
- (2017) David A. Patten et al. JOURNAL OF ALZHEIMERS DISEASE
- Mitochondria Dysfunction and Neurodegenerative Disorders: Cause or Consequence
- (2017) Vanessa A. Morais et al. JOURNAL OF ALZHEIMERS DISEASE
- Factors secreted from dental pulp stem cells show multifaceted benefits for treating experimental rheumatoid arthritis
- (2016) Jun Ishikawa et al. BONE
- Therapeutic effects of intranigral transplantation of mesenchymal stem cells in rat models of Parkinson's disease
- (2016) Dandan Chen et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Exosome-mediated transfer of miR-222 is sufficient to increase tumor malignancy in melanoma
- (2016) Federica Felicetti et al. Journal of Translational Medicine
- Prospects for bone marrow cell therapy in amyotrophic lateral sclerosis: how far are we from a clinical treatment?
- (2016) Fernanda Gubert et al. Neural Regeneration Research
- Extracellular Vesicles in Physiology, Pathology, and Therapy of the Immune and Central Nervous System, with Focus on Extracellular Vesicles Derived from Mesenchymal Stem Cells as Therapeutic Tools
- (2016) Sylwia Koniusz et al. Frontiers in Cellular Neuroscience
- Functional characterization of human umbilical cord-derived mesenchymal stem cells for treatment of systolic heart failure
- (2016) Zhihua Fang et al. Experimental and Therapeutic Medicine
- Mesenchymal Stem Cells Modulate the Functional Properties of Microglia via TGF-β Secretion
- (2016) Min Young Noh et al. Stem Cells Translational Medicine
- Exosomes from dental pulp stem cells rescue human dopaminergic neurons from 6-hydroxy-dopamine–induced apoptosis
- (2015) Akvilė Jarmalavičiūtė et al. CYTOTHERAPY
- Exosomes as drug delivery vehicles for Parkinson's disease therapy
- (2015) Matthew J. Haney et al. JOURNAL OF CONTROLLED RELEASE
- Effect of exosomes derived from multipluripotent mesenchymal stromal cells on functional recovery and neurovascular plasticity in rats after traumatic brain injury
- (2015) Yanlu Zhang et al. JOURNAL OF NEUROSURGERY
- Mesenchymal Stem Cell-derived Extracellular Vesicles: Toward Cell-free Therapeutic Applications
- (2015) Sweta Rani et al. MOLECULAR THERAPY
- Aβ and NMDAR activation cause mitochondrial dysfunction involving ER calcium release
- (2015) Ildete Luísa Ferreira et al. NEUROBIOLOGY OF AGING
- Chromatographically isolated CD63+CD81+extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments after TBI
- (2015) Dong-ki Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pancreatic cancer-derived exosomes transfer miRNAs to dendritic cells and inhibit RFXAP expression via miR-212-3p
- (2015) Guoping Ding et al. Oncotarget
- Extracellular membrane vesicles as a mechanism of cell-to-cell communication: advantages and disadvantages
- (2014) Giuseppina Turturici et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles
- (2014) Marina Colombo et al. Annual Review of Cell and Developmental Biology
- Future directions in Alzheimer's disease from risk factors to prevention
- (2014) Bushra Imtiaz et al. BIOCHEMICAL PHARMACOLOGY
- Transplantation of bone marrow mesenchymal stem cells decreases oxidative stress, apoptosis, and hippocampal damage in brain of a spontaneous stroke model
- (2014) Michele Longoni Calió et al. FREE RADICAL BIOLOGY AND MEDICINE
- Alzheimer's Disease-Like Pathology Induced by Amyloid-β Oligomers in Nonhuman Primates
- (2014) Leticia Forny-Germano et al. JOURNAL OF NEUROSCIENCE
- The Anti-Oxidative Role of Micro-Vesicles Derived from Human Wharton-Jelly Mesenchymal Stromal Cells through NOX2/gp91(phox) Suppression in Alleviating Renal Ischemia-Reperfusion Injury in Rats
- (2014) Guangyuan Zhang et al. PLoS One
- Distribution of Mesenchymal Stem Cells and Effects on Neuronal Survival and Axon Regeneration after Optic Nerve Crush and Cell Therapy
- (2014) Louise Alessandra Mesentier-Louro et al. PLoS One
- TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer’s β-Amyloid Oligomers in Mice and Monkeys
- (2013) Mychael V. Lourenco et al. Cell Metabolism
- Alzheimer´s Disease and Oxidative Stress: A Review
- (2013) Miroslav Pohanka CURRENT MEDICINAL CHEMISTRY
- Extracellular vesicles: Exosomes, microvesicles, and friends
- (2013) Graça Raposo et al. JOURNAL OF CELL BIOLOGY
- Systemic Administration of Exosomes Released from Mesenchymal Stromal Cells Promote Functional Recovery and Neurovascular Plasticity After Stroke in Rats
- (2013) Hongqi Xin et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Memantine Rescues Transient Cognitive Impairment Caused by High-Molecular-Weight A Oligomers But Not the Persistent Impairment Induced by Low-Molecular-Weight Oligomers
- (2013) C. P. Figueiredo et al. JOURNAL OF NEUROSCIENCE
- Emerging roles of astrocytes in neural circuit development
- (2013) Laura E. Clarke et al. NATURE REVIEWS NEUROSCIENCE
- Therapeutics of Alzheimer's disease: Past, present and future
- (2013) R. Anand et al. NEUROPHARMACOLOGY
- MiR-133b Promotes Neural Plasticity and Functional Recovery After Treatment of Stroke with Multipotent Mesenchymal Stromal Cells in Rats Via Transfer of Exosome-Enriched Extracellular Particles
- (2013) Hongqi Xin et al. STEM CELLS
- Mesenchymal stem cell-derived secretome and microvesicles as a cell-free therapeutics for neurodegenerative disorders
- (2013) Hyun Ok Kim et al. Tissue Engineering and Regenerative Medicine
- Placenta-derived mesenchymal stem cells improve memory dysfunction in an Aβ1–42-infused mouse model of Alzheimer’s disease
- (2013) H-M Yun et al. Cell Death & Disease
- Human adipose tissue-derived mesenchymal stem cells secrete functional neprilysin-bound exosomes
- (2013) Takeshi Katsuda et al. Scientific Reports
- Neurotoxicity of Amyloid -Protein: Synaptic and Network Dysfunction
- (2013) L. Mucke et al. Cold Spring Harbor Perspectives in Medicine
- Human Mesenchymal Stem Cells Increase Anti-oxidant Defences in Cells Derived from Patients with Friedreich’s Ataxia
- (2012) Rimi Dey et al. CEREBELLUM
- Amyloid-β Oligomers Induce Differential Gene Expression in Adult Human Brain Slices
- (2012) Adriano Sebollela et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondria, oxidative stress and neurodegeneration
- (2012) Antonio Federico et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- From Mitochondrial Dysfunction to Amyloid Beta Formation: Novel Insights into the Pathogenesis of Alzheimer’s Disease
- (2012) Kristina Leuner et al. MOLECULAR NEUROBIOLOGY
- Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice
- (2012) J H Ledo et al. MOLECULAR PSYCHIATRY
- Neuroprotective effects and magnetic resonance imaging of mesenchymal stem cells labeled with SPION in a rat model of Huntington's disease
- (2012) Louise Moraes et al. Stem Cell Research
- Bone Marrow–derived Mesenchymal Stem Cells Transplantation Accelerates Tissue Expansion by Promoting Skin Regeneration During Expansion
- (2011) Mei Yang et al. ANNALS OF SURGERY
- Soluble intracellular adhesion molecule-1 secreted by human umbilical cord blood-derived mesenchymal stem cell reduces amyloid-β plaques
- (2011) J-Y Kim et al. CELL DEATH AND DIFFERENTIATION
- Bone Marrow Mesenchymal Stem Cells in a Three-Dimensional Gelatin Sponge Scaffold Attenuate Inflammation, Promote Angiogenesis, and Reduce Cavity Formation in Experimental Spinal Cord Injury
- (2011) Xiang Zeng et al. CELL TRANSPLANTATION
- Aβ Oligomers Induce Glutamate Release from Hippocampal Neurons
- (2011) J. Brito-Moreira et al. Current Alzheimer Research
- The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer’s disease
- (2011) Sergio T. Ferreira et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Action at a Distance: Systemically Administered Adult Stem/Progenitor Cells (MSCs) Reduce Inflammatory Damage to the Cornea Without Engraftment and Primarily by Secretion of TNF-α Stimulated Gene/Protein 6
- (2011) Gavin W. Roddy et al. STEM CELLS
- Concise Review: Mesenchymal Stem Cells for Acute Lung Injury: Role of Paracrine Soluble Factors
- (2011) Jae W. Lee et al. STEM CELLS
- Amyloid β-Peptide Oligomers Stimulate RyR-Mediated Ca2+ Release Inducing Mitochondrial Fragmentation in Hippocampal Neurons and Prevent RyR-Mediated Dendritic Spine Remodeling Produced by BDNF
- (2010) Andrea C. Paula-Lima et al. ANTIOXIDANTS & REDOX SIGNALING
- Activation of D1/D5 Dopamine Receptors Protects Neurons from Synapse Dysfunction Induced by Amyloid-β Oligomers
- (2010) Sofia Jürgensen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- N-Methyl-d-aspartate receptors are required for synaptic targeting of Alzheimer’s toxic amyloid-β peptide oligomers
- (2010) Helena Decker et al. JOURNAL OF NEUROCHEMISTRY
- Human umbilical cord blood-derived mesenchymal stem cells improve neuropathology and cognitive impairment in an Alzheimer's disease mouse model through modulation of neuroinflammation
- (2010) Hyun Ju Lee et al. NEUROBIOLOGY OF AGING
- Amyloid-β Triggers the Release of Neuronal Hexokinase 1 from Mitochondria
- (2010) Leonardo M. Saraiva et al. PLoS One
- Human Mesenchymal Stem Cells Efficiently Manage Oxidative Stress
- (2010) Araceli Valle-Prieto et al. STEM CELLS AND DEVELOPMENT
- Airway Delivery of Mesenchymal Stem Cells Prevents Arrested Alveolar Growth in Neonatal Lung Injury in Rats
- (2009) Timothy van Haaften et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Therapeutic window for treatment of cortical ischemia with bone marrow-derived cells in rats
- (2009) Andréia de Vasconcelos dos Santos et al. BRAIN RESEARCH
- Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers
- (2009) Fernanda G. De Felice et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bone marrow-derived mesenchymal stem cells reduce brain amyloid-β deposition and accelerate the activation of microglia in an acutely induced Alzheimer's disease mouse model
- (2008) Jong Kil Lee et al. NEUROSCIENCE LETTERS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now