Human Mesenchymal Stem Cells Increase Anti-oxidant Defences in Cells Derived from Patients with Friedreich’s Ataxia

The cerebellar component of Friedreich’s ataxia

(2011) Arnulf H. Koeppen et al.   ACTA NEUROPATHOLOGICA

Friedreich's ataxia: the vicious circle hypothesis revisited

(2011) Aurélien Bayot et al.   BMC Medicine

Preventing the ubiquitin–proteasome-dependent degradation of frataxin, the protein defective in Friedreich's ataxia

(2011) Alessandra Rufini et al.   HUMAN MOLECULAR GENETICS

Exploring frataxin function

(2011) Maria V. Busi et al.   IUBMB LIFE

Friedreich's ataxia: Pathology, pathogenesis, and molecular genetics

(2011) Arnulf H. Koeppen   JOURNAL OF THE NEUROLOGICAL SCIENCES

Differential Expression of PGC-1α and Metabolic Sensors Suggest Age-Dependent Induction of Mitochondrial Biogenesis in Friedreich Ataxia Fibroblasts

(2011) José Luis García-Giménez et al.   PLoS One

Mesenchymal Stem Cells Restore Frataxin Expression and Increase Hydrogen Peroxide Scavenging Enzymes in Friedreich Ataxia Fibroblasts

(2011) Kevin Kemp et al.   PLoS One

Friedreich Ataxia: Molecular Mechanisms, Redox Considerations, and Therapeutic Opportunities

(2010) Renata Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

Combined Therapy with Idebenone and Deferiprone in Patients with Friedreich’s Ataxia

(2010) Daniel Velasco-Sánchez et al.   CEREBELLUM

Does oxidative stress contribute to the pathology of Friedreich’s ataxia? A radical question

(2010) Jeffrey S. Armstrong et al.   FASEB JOURNAL

Characterization of in vitro expanded bone marrow-derived mesenchymal stem cells from patients with multiple sclerosis

(2010) Elizabeth Mallam et al.   Multiple Sclerosis Journal

Fusion between human mesenchymal stem cells and rodent cerebellar Purkinje cells

(2010) K. Kemp et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Inflammatory Cytokine Induced Regulation of Superoxide Dismutase 3 Expression by Human Mesenchymal Stem Cells

(2010) Kevin Kemp et al.   Stem Cell Reviews and Reports

Mitochondrial Nitric Oxide Synthase: A Masterpiece of Metabolic Adaptation, Cell Growth, Transformation, and Death

(2009) Paola V. Finocchietto et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Yeast frataxin mutants display decreased superoxide dismutase activity crucial to promote protein oxidative damage

(2009) Verónica Irazusta et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mesenchymal stem cell-secreted superoxide dismutase promotes cerebellar neuronal survival

(2009) Kevin Kemp et al.   JOURNAL OF NEUROCHEMISTRY

Friedreich ataxia: The clinical picture

(2009) Massimo Pandolfo   JOURNAL OF NEUROLOGY

The pathogenesis of Friedreich ataxia and the structure and function of frataxin

(2009) Massimo Pandolfo et al.   JOURNAL OF NEUROLOGY

Friedreich's ataxia: Oxidative stress and cytoskeletal abnormalities

(2009) Marco Sparaco et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Impaired Nuclear Nrf2 Translocation Undermines the Oxidative Stress Response in Friedreich Ataxia

(2009) Vincent Paupe et al.   PLoS One

Human bone marrow-derived mesenchymal stem cells secrete brain-derived neurotrophic factor which promotes neuronal survival in vitro

(2009) Alastair Wilkins et al.   Stem Cell Research

Recombinant Human Erythropoietin Increases Frataxin Protein Expression Without Increasing mRNA Expression

(2008) Fabio Acquaviva et al.   CEREBELLUM