Air pollution-derived particulate matter dysregulates hepatic Krebs cycle, glucose and lipid metabolism in mice

Combined effects of ambient particulate matter exposure and a high-fat diet on oxidative stress and steatohepatitis in mice

(2019) Shibin Ding et al.   PLoS One

Metabolomics analysis of a mouse model for chronic exposure to ambient PM2.5

(2019) Yanyi Xu et al.   ENVIRONMENTAL POLLUTION

Ambient fine particulate matter exposure induces cardiac functional injury and metabolite alterations in middle-aged female mice

(2019) Yingying Zhang et al.   ENVIRONMENTAL POLLUTION

Fine particles cause the abnormality of cardiac ATP levels via PPARɑ-mediated utilization of fatty acid and glucose using in vivo and in vitro models

(2019) Xiaoting Jin et al.   ENVIRONMENTAL POLLUTION

Identification of multiple dysregulated metabolic pathways by GC-MS-based profiling of liver tissue in mice with OVA-induced asthma exposed to PM2.5

(2019) Zhentao Wang et al.   CHEMOSPHERE

Comprehensive metabolic responses of HepG2 cells to fine particulate matter exposure: Insights from an untargeted metabolomics

(2019) Guozhu Ye et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Combination effects of airborne particulate matter exposure and high-fat diet on hepatic fibrosis through regulating the ROS-endoplasmic reticulum stress-TGFβ/SMADs axis in mice

(2018) Shibin Ding et al.   CHEMOSPHERE

Metabolic impact induced by total, water soluble and insoluble components of PM 2.5 acute exposure in mice

(2018) Yannan Zhang et al.   CHEMOSPHERE

De novo lipogenesis represents a therapeutic target in mutant Kras non-small cell lung cancer

(2018) Anju Singh et al.   FASEB JOURNAL

Primary genotoxicity in the liver following pulmonary exposure to carbon black nanoparticles in mice

(2018) Justyna Modrzynska et al.   Particle and Fibre Toxicology

Seasonal variations in fine particle composition from Beijing prompt oxidative stress response in mouse lung and liver

(2018) Michal Pardo et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Source impact modeling of spatiotemporal trends in PM2.5 oxidative potential across the eastern United States

(2018) Josephine T. Bates et al.   ATMOSPHERIC ENVIRONMENT

iRhom2 loss alleviates renal injury in long-term PM2.5-exposed mice by suppression of inflammation and oxidative stress

(2018) Ge Chenxu et al.   Redox Biology

Water soluble and insoluble components of PM2.5 and their functional cardiotoxicities on neonatal rat cardiomyocytes in vitro

(2018) Zenghua Qi et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Air Pollution and Cardiovascular Disease

(2018) Sanjay Rajagopalan et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Particulate Matter Air Pollution: Effects on the Cardiovascular System

(2018) Robert B. Hamanaka et al.   Frontiers in Endocrinology

Identification of multiple dysregulated metabolic pathways by GC-MS-based profiling of lung tissue in mice with PM2.5-induced asthma

(2018) Zhentao Wang et al.   CHEMOSPHERE

Inhaled Pollutants: The Molecular Scene behind Respiratory and Systemic Diseases Associated with Ultrafine Particulate Matter

(2017) Hussein Traboulsi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exploring cancer metabolism using stable isotope-resolved metabolomics (SIRM)

(2017) Ronald C. Bruntz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Probing the metabolic phenotype of breast cancer cells by multiple tracer stable isotope resolved metabolomics

(2017) Andrew N. Lane et al.   METABOLIC ENGINEERING

Particulate Air pollution mediated effects on insulin resistance in mice are independent of CCR2

(2017) Cuiqing Liu et al.   Particle and Fibre Toxicology

Mitochondrial toxicity of tobacco smoke and air pollution

(2017) Jessica L. Fetterman et al.   TOXICOLOGY

Unraveling the Regulation of Hepatic Metabolism by Insulin

(2017) Paul M. Titchenell et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Differences in inflammation and acute phase response but similar genotoxicity in mice following pulmonary exposure to graphene oxide and reduced graphene oxide

(2017) Stefan Bengtson et al.   PLoS One

MiR-1271 upregulated by saturated fatty acid palmitate provokes impaired insulin signaling by repressing INSR and IRS-1 expression in HepG2 cells

(2016) Won-Mo Yang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of lipids in the pathogenesis and treatment of type 2 diabetes and associated co-morbidities

(2016) Derek M. Erion et al.   BMB Reports

Acute exposure to Buenos Aires air particles (UAP-BA) induces local and systemic inflammatory response in middle-aged mice: A time course study

(2016) Nadia S. Orona et al.   ENVIRONMENTAL POLLUTION

Hepatic adaptations to maintain metabolic homeostasis in response to fasting and refeeding in mice

(2016) C. E. Geisler et al.   Nutrition & Metabolism

Adaptation of Hepatic Mitochondrial Function in Humans with Non-Alcoholic Fatty Liver Is Lost in Steatohepatitis

(2015) Chrysi Koliaki et al.   Cell Metabolism

Pyruvate carboxylase is critical for non–small-cell lung cancer proliferation

(2015) Katherine Sellers et al.   JOURNAL OF CLINICAL INVESTIGATION

Exposure to fine airborne particulate matters induces hepatic fibrosis in murine models

(2015) Ze Zheng et al.   JOURNAL OF HEPATOLOGY

In Vivo Exposures to Particulate Matter Collected from Saudi Arabia or Nickel Chloride Display Similar Dysregulation of Metabolic Syndrome Genes

(2015) Jason Brocato et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth

(2015) Emily D. Montal et al.   MOLECULAR CELL

The contribution of outdoor air pollution sources to premature mortality on a global scale

(2015) J. Lelieveld et al.   NATURE

Aerosol particulate matter in the Baltimore metropolitan area: Temporal variation over a six-year period

(2015) Daniel Orozco et al.   JOURNAL OF THE AIR & WASTE MANAGEMENT ASSOCIATION

Long-Term Exposure to Ambient Air Pollution and Metabolic Syndrome in Adults

(2015) Ikenna C. Eze et al.   PLoS One

Air Pollution as a Risk Factor for Type 2 Diabetes

(2015) Xiaoquan Rao et al.   TOXICOLOGICAL SCIENCES

Repeated Intratracheal Instillation of PM10 Induces Lipid Reshaping in Lung Parenchyma and in Extra-Pulmonary Tissues

(2014) Angela Maria Rizzo et al.   PLoS One

Diesel Exhaust Induces Systemic Lipid Peroxidation and Development of Dysfunctional Pro-Oxidant and Pro-Inflammatory High-Density Lipoprotein

(2013) Fen Yin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Air Pollution–Mediated Susceptibility to Inflammation and Insulin Resistance: Influence of CCR2 Pathways in Mice

(2013) Cuiqing Liu et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Increased De Novo Lipogenesis Is a Distinct Characteristic of Individuals With Nonalcoholic Fatty Liver Disease

(2013) Jennifer E. Lambert et al.   GASTROENTEROLOGY

Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis

(2013) Anju Singh et al.   JOURNAL OF CLINICAL INVESTIGATION

Correcting for the effects of natural abundance in stable isotope resolved metabolomics experiments involving ultra-high resolution mass spectrometry

(2012) Hunter NB Moseley   BMC BIOINFORMATICS

From lung to liver: How does airborne particulate matter trigger NASH and systemic insulin resistance?

(2012) Daniel J. Conklin   JOURNAL OF HEPATOLOGY

Exposure to ambient particulate matter induces a NASH-like phenotype and impairs hepatic glucose metabolism in an animal model

(2012) Ze Zheng et al.   JOURNAL OF HEPATOLOGY

Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver

(2012) Julie A Bourdon et al.   Particle and Fibre Toxicology

Effect of co-exposure to nickel and particulate matter on insulin resistance and mitochondrial dysfunction in a mouse model

(2012) Xiaohua Xu et al.   Particle and Fibre Toxicology

Liver ATP Synthesis Is Lower and Relates to Insulin Sensitivity in Patients With Type 2 Diabetes

(2011) A. I. Schmid et al.   DIABETES CARE

Effects of spaced feeding on gene expression of hepatic transaminase and gluconeogenic enzymes in rats

(2011) Akio Kobayashi et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

High information throughput analysis of nucleotides and their isotopically enriched isotopologues by direct-infusion FTICR-MS

(2011) Pawel Lorkiewicz et al.   Metabolomics

Long-term Exposure to Ambient Fine Particulate Pollution Induces Insulin Resistance and Mitochondrial Alteration in Adipose Tissue

(2011) Xiaohua Xu et al.   TOXICOLOGICAL SCIENCES

Stable isotope resolved metabolomics of lung cancer in a SCID mouse model

(2010) Teresa W.-M. Fan et al.   Metabolomics

Diacylglycerol-mediated insulin resistance

(2010) Derek M Erion et al.   NATURE MEDICINE

Liver and Adipose Expression Associated SNPs Are Enriched for Association to Type 2 Diabetes

(2010) Hua Zhong et al.   PLoS Genetics

Reduced TCA flux in diabetic myotubes: A governing influence on the diabetic phenotype?

(2009) Michael Gaster   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ambient Air Pollution Exaggerates Adipose Inflammation and Insulin Resistance in a Mouse Model of Diet-Induced Obesity

(2009) Qinghua Sun et al.   CIRCULATION

The mitochondrial citrate carrier: Metabolic role and regulation of its activity and expression

(2009) Gabriele V. Gnoni et al.   IUBMB LIFE

Kupffer cell activation by ambient air particulate matter exposure may exacerbate non-alcoholic fatty liver disease

(2009) Hui-Hui Tan et al.   Journal of Immunotoxicology

Influence of Different Sizes of Titanium Dioxide Nanoparticles on Hepatic and Renal Functions in Rats with Correlation to Oxidative Stress

(2009) Geyu Liang et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Reduced tricarboxylic acid cycle flux in type 2 diabetes mellitus?

(2008) P. Schrauwen et al.   DIABETOLOGIA

Structure-based profiling of metabolites and isotopomers by NMR

(2007) Teresa W.-M. Fan et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY