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Title
TBK1 Limits mTORC1 by Promoting Phosphorylation of Raptor Ser877
Authors
Keywords
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Journal
Scientific Reports
Volume 9, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-09-17
DOI
10.1038/s41598-019-49707-8
References
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Note: Only part of the references are listed.- mTORC1 and mTORC2 as regulators of cell metabolism in immunity
- (2017) Monika Linke et al. FEBS LETTERS
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- (2017) Qian Zhang et al. NATURE CELL BIOLOGY
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- (2017) Maroof Hasan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Anthelmintic drug ivermectin inhibits angiogenesis, growth and survival of glioblastoma through inducing mitochondrial dysfunction and oxidative stress
- (2016) Yingying Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Characterization of Hippo Pathway Components by Gene Inactivation
- (2016) Steven W. Plouffe et al. MOLECULAR CELL
- Phosphorylation of OPTN by TBK1 enhances its binding to Ub chains and promotes selective autophagy of damaged mitochondria
- (2016) Benjamin Richter et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tor forms a dimer through an N-terminal helical solenoid with a complex topology
- (2016) Domagoj Baretić et al. Nature Communications
- 4.4 Å Resolution Cryo-EM structure of human mTOR Complex 1
- (2016) Huirong Yang et al. Protein & Cell
- NLK phosphorylates Raptor to mediate stress-induced mTORC1 inhibition
- (2015) Hai-Xin Yuan et al. GENES & DEVELOPMENT
- Architecture of human mTOR complex 1
- (2015) C. H. S. Aylett et al. SCIENCE
- Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis
- (2015) Smitha Pillai et al. Nature Communications
- TBK1 Regulates Prostate Cancer Dormancy through mTOR Inhibition
- (2015) Jin Koo Kim et al. NEOPLASIA
- Recent insights into the complexity of Tank-binding kinase 1 signaling networks: The emerging role of cellular localization in the activation and substrate specificity of TBK1
- (2013) Elizabeth Helgason et al. FEBS LETTERS
- Dissection of TBK1 signaling via phosphoproteomics in lung cancer cells
- (2013) J.-Y. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation
- (2012) Manohar Pilli et al. IMMUNITY
- NIH Image to ImageJ: 25 years of image analysis
- (2012) Caroline A Schneider et al. NATURE METHODS
- Development of a High-Throughput Assay for Identifying Inhibitors of TBK1 and IKKε
- (2012) Jessica E. Hutti et al. PLoS One
- The Identification of Raptor as a Substrate for p44/42 MAPK
- (2011) Paul Langlais et al. ENDOCRINOLOGY
- The Mechanism of Insulin-stimulated 4E-BP Protein Binding to Mammalian Target of Rapamycin (mTOR) Complex 1 and Its Contribution to mTOR Complex 1 Signaling
- (2011) Joseph Rapley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Universal and Confident Phosphorylation Site Localization Using phosphoRS
- (2011) Thomas Taus et al. JOURNAL OF PROTEOME RESEARCH
- TBK1 Directly Engages Akt/PKB Survival Signaling to Support Oncogenic Transformation
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- Structure of the Human mTOR Complex I and Its Implications for Rapamycin Inhibition
- (2010) Calvin K. Yip et al. MOLECULAR CELL
- Raptor is Phosphorylated by cdc2 during Mitosis
- (2010) Dana M. Gwinn et al. PLoS One
- Mammalian Target of Rapamycin Complex 1 (mTORC1) Activity Is Associated with Phosphorylation of Raptor by mTOR
- (2009) Lifu Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of mTOR Complex 1 (mTORC1) by Raptor Ser863and Multisite Phosphorylation
- (2009) Kathryn G. Foster et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
- (2009) David A. Barbie et al. NATURE
- The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune response
- (2008) Didier Soulat et al. EMBO JOURNAL
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