Screening inducers of neuronal BDNF gene transcription using primary cortical cell cultures from BDNF-luciferase transgenic mice

Panax ginseng exerts antidepressant-like effects by suppressing neuroinflammatory response and upregulating nuclear factor erythroid 2 related factor 2 signaling in the amygdala

(2018) Jong Hee Choi et al.   Journal of Ginseng Research

Panax ginseng as an adjuvant treatment for Alzheimer's disease

(2018) Hyeon-Joong Kim et al.   Journal of Ginseng Research

Actions of Brain-Derived Neurotrophin Factor in the Neurogenesis and Neuronal Function, and Its Involvement in the Pathophysiology of Brain Diseases

(2018) Tadahiro Numakawa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Convergence of neurotransmissions at synapse on IEG regulation in nucleus

(2017) Mamoru Fukuchi   Frontiers in Bioscience-Landmark

Effects of ginseng on stress-related depression, anxiety, and the hypothalamic–pituitary–adrenal axis

(2017) Seungyeop Lee et al.   Journal of Ginseng Research

Visualizing changes in brain-derived neurotrophic factor (BDNF) expression using bioluminescence imaging in living mice

(2017) Mamoru Fukuchi et al.   Scientific Reports

Ginsenoside Rg1 ameliorates hippocampal long-term potentiation and memory in an Alzheimer's disease model

(2016) FENGLING LI et al.   Molecular Medicine Reports

Higher brainBDNFgene expression is associated with slower cognitive decline in older adults

(2016) Aron S. Buchman et al.   NEUROLOGY

7,8-Dihydroxyflavone reverses the depressive symptoms in mouse chronic mild stress

(2016) Min-Wang Zhang et al.   NEUROSCIENCE LETTERS

Convergent effects of Ca2+ and cAMP signals on the expression of immediate early genes in neurons

(2015) Mamoru Fukuchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Antidepressant Effects of TrkB Ligands on Depression-Like Behavior and Dendritic Changes in Mice After Inflammation

(2015) Ji-chun Zhang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Neuromodulatory Effect of G s- or G q-Coupled G-Protein-Coupled Receptor on NMDA Receptor Selectively Activates the NMDA Receptor/Ca2+/Calcineurin/cAMP Response Element-Binding Protein-Regulated Transcriptional Coactivator 1 Pathway to Effectively Induce Brain-Derived Neurotrophic Factor Expression in Neurons

(2015) M. Fukuchi et al.   JOURNAL OF NEUROSCIENCE

Lower Cerebrospinal Fluid Concentration of Brain-Derived Neurotrophic Factor Predicts Progression from Mild Cognitive Impairment to Alzheimer’s Disease

(2015) Orestes Vicente Forlenza et al.   NEUROMOLECULAR MEDICINE

BAC-based cellular model for screening regulators of BDNF gene transcription

(2014) Kaur Jaanson et al.   BMC NEUROSCIENCE

LPA receptor signaling: pharmacology, physiology, and pathophysiology

(2014) Yun C. Yung et al.   JOURNAL OF LIPID RESEARCH

Excitatory GABA induces BDNF transcription via CRTC1 and phosphorylated CREB-related pathways in immature cortical cells

(2014) Mamoru Fukuchi et al.   JOURNAL OF NEUROCHEMISTRY

Towards a better understanding of cognitive behaviors regulated by gene expression downstream of activity-dependent transcription factors

(2014) Mio Nonaka et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Small-molecule TrkB agonist 7,8-dihydroxyflavone reverses cognitive and synaptic plasticity deficits in a rat model of schizophrenia

(2014) Yuan-Jian Yang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

7,8-Dihydroxyflavone, a Small Molecule TrkB Agonist, Improves Spatial Memory and Increases Thin Spine Density in a Mouse Model of Alzheimer Disease-Like Neuronal Loss

(2014) Nicholas A. Castello et al.   PLoS One

7,8-Dihydroxyflavone Prevents Synaptic Loss and Memory Deficits in a Mouse Model of Alzheimer’s Disease

(2013) Zhentao Zhang et al.   NEUROPSYCHOPHARMACOLOGY

Measuring CREB Activation Using Bioluminescent Probes That Detect KID–KIX Interaction in Living Cells

(2012) Tetsuya Ishimoto et al.   BIOCONJUGATE CHEMISTRY

Antidepressant-like effects of ginsenoside Rg1 are due to activation of the BDNF signalling pathway and neurogenesis in the hippocampus

(2012) Bo Jiang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Gintonin, newly identified compounds from ginseng, is novel lysophosphatidic acids-protein complexes and activates G protein-coupled lysophosphatidic acid receptors with high affinity

(2012) Sung Hee Hwang et al.   MOLECULES AND CELLS

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

Fingolimod, a sphingosine-1 phosphate receptor modulator, increases BDNF levels and improves symptoms of a mouse model of Rett syndrome

(2012) R. Deogracias et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The hydrophobic dipeptide Leu–Ile inhibits immobility induced by repeated forced swimming via the induction of BDNF

(2011) Yoko Furukawa-Hibi et al.   BEHAVIOURAL BRAIN RESEARCH

A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone

(2010) S.-W. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA