Sharing of heteroplasmies between human liver lobes varies across the mtDNA genome

A Population Phylogenetic View of Mitochondrial Heteroplasmy

(2018) Peter R. Wilton et al.   GENETICS

Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos

(2018) Vasileios I. Floros et al.   NATURE CELL BIOLOGY

Large-scale genetic analysis reveals mammalian mtDNA heteroplasmy dynamics and variance increase through lifetimes and generations

(2018) Joerg P. Burgstaller et al.   Nature Communications

A Population Phylogenetic View of Mitochondrial Heteroplasmy

(2018) Peter R. Wilton et al.   GENETICS

Evidence for cell-free nucleic acids as continuously arising endogenous DNA mutagens

(2016) Ranjan Basak et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Revised Estimates for the Number of Human and Bacteria Cells in the Body

(2016) Ron Sender et al.   PLOS BIOLOGY

Age-Related and Heteroplasmy-Related Variation in Human mtDNA Copy Number

(2016) Manja Wachsmuth et al.   PLoS Genetics

Evidence for frequent and tissue-specific sequence heteroplasmy in human mitochondrial DNA

(2015) Jana Naue et al.   MITOCHONDRION

Mitochondrial DNA mutations in single human blood cells

(2015) Yong-Gang Yao et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease

(2015) James B. Stewart et al.   NATURE REVIEWS GENETICS

Stable heteroplasmy at the single-cell level is facilitated by intercellular exchange of mtDNA

(2015) Anitha D. Jayaprakash et al.   NUCLEIC ACIDS RESEARCH

Extensive tissue-related and allele-related mtDNA heteroplasmy suggests positive selection for somatic mutations

(2015) Mingkun Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Liver Stem Cells, Where Art Thou?

(2014) Markus Grompe   Cell Stem Cell

In D-loop: 40years of mitochondrial 7S DNA

(2014) Thomas J. Nicholls et al.   EXPERIMENTAL GERONTOLOGY

MitImpact: an Exhaustive Collection of Pre-computed Pathogenicity Predictions of Human Mitochondrial Non-synonymous Variants

(2014) Stefano Castellana et al.   HUMAN MUTATION

leeHom: adaptor trimming and merging for Illumina sequencing reads

(2014) Gabriel Renaud et al.   NUCLEIC ACIDS RESEARCH

Extensive pathogenicity of mitochondrial heteroplasmy in healthy human individuals

(2014) K. Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA

(2014) B. Rebolledo-Jaramillo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An estimation of the number of cells in the human body

(2013) Eva Bianconi et al.   ANNALS OF HUMAN BIOLOGY

freeIbis: an efficient basecaller with calibrated quality scores for Illumina sequencers

(2013) Gabriel Renaud et al.   BIOINFORMATICS

Functional Recurrent Mutations in the Human Mitochondrial Phylogeny: Dual Roles in Evolution and Disease

(2013) Liron Levin et al.   Genome Biology and Evolution

Very Low-Level Heteroplasmy mtDNA Variations Are Inherited in Humans

(2013) Yan Guo et al.   Journal of Genetics and Genomics

When Cells Become Organelle Donors

(2013) Robert S. Rogers et al.   PHYSIOLOGY

Mitochondrial DNA Genetics and the Heteroplasmy Conundrum in Evolution and Disease

(2013) D. C. Wallace et al.   Cold Spring Harbor Perspectives in Biology

Recurrent Tissue-Specific mtDNA Mutations Are Common in Humans

(2013) David C. Samuels et al.   PLoS Genetics

Is mitochondrial DNA turnover slower than commonly assumed?

(2012) Suresh Kumar Poovathingal et al.   BIOGERONTOLOGY

Mitochondrial DNA heteroplasmy in diabetes and normal adults: role of acquired and inherited mutational patterns in twins

(2012) Gal Avital et al.   HUMAN MOLECULAR GENETICS

Universal heteroplasmy of human mitochondrial DNA

(2012) B. A. I. Payne et al.   HUMAN MOLECULAR GENETICS

Non-Random mtDNA Segregation Patterns Indicate a Metastable Heteroplasmic Segregation Unit in m.3243A>G Cybrid Cells

(2012) Anton K. Raap et al.   PLoS One

A new approach for detecting low-level mutations in next-generation sequence data

(2012) Mingkun Li et al.   GENOME BIOLOGY

Predicting the functional impact of protein mutations: application to cancer genomics

(2011) Boris Reva et al.   NUCLEIC ACIDS RESEARCH

Evolution of the mitochondrial fusion-fission cycle and its role in aging

(2011) A. Kowald et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detecting Heteroplasmy from High-Throughput Sequencing of Complete Human Mitochondrial DNA Genomes

(2010) Mingkun Li et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Somatic Mitochondrial DNA Mutations in Mammalian Aging

(2010) Nils-Göran Larsson   Annual Review of Biochemistry

Differential regulation of full-length genome and a single-stranded 7S DNA along the cell cycle in human mitochondria

(2010) Anita Antes et al.   NUCLEIC ACIDS RESEARCH

Multiplexed DNA Sequence Capture of Mitochondrial Genomes Using PCR Products

(2010) Tomislav Maricic et al.   PLoS One

KaKs_Calculator 2.0: A Toolkit Incorporating Gamma-Series Methods and Sliding Window Strategies

(2010) Dapeng Wang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Correcting for Purifying Selection: An Improved Human Mitochondrial Molecular Clock

(2009) Pedro Soares et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Circulating DNA

(2009) Maniesh van der Vaart et al.   Annals of the New York Academy of Sciences

Stochastic Drift in Mitochondrial DNA Point Mutations: A Novel Perspective Ex Silico

(2009) Suresh Kumar Poovathingal et al.   PLoS Computational Biology

Mitochondrial turnover in liver is fastin vivoand is accelerated by dietary restriction: application of a simple dynamic model

(2008) Satomi Miwa et al.   AGING CELL

Strong Purifying Selection in Transmission of Mammalian Mitochondrial DNA

(2008) James Bruce Stewart et al.   PLOS BIOLOGY