Novel insights into host-fungal pathogen interactions derived from live-cell imaging

Distinct Innate Immune Phagocyte Responses to Aspergillus fumigatus Conidia and Hyphae in Zebrafish Larvae

(2014) Benjamin P. Knox et al.   EUKARYOTIC CELL

In vivo imaging of disseminated murine Candida albicans infection reveals unexpected host sites of fungal persistence during antifungal therapy

(2014) Ilse D. Jacobsen et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Hyphal Growth of Phagocytosed Fusarium oxysporum Causes Cell Lysis and Death of Murine Macrophages

(2014) Katja Schäfer et al.   PLoS One

A neglected epidemic: fungal infections in HIV/AIDS

(2014) Darius Armstrong-James et al.   TRENDS IN MICROBIOLOGY

Illuminating Fungal Infections with Bioluminescence

(2014) Nicolas Papon et al.   PLoS Pathogens

Catching Fire: Candida albicans, Macrophages, and Pyroptosis

(2014) Damian J. Krysan et al.   PLoS Pathogens

Ybp1 and Gpx3 Signaling in Candida albicans Govern Hydrogen Peroxide-Induced Oxidation of the Cap1 Transcription Factor and Macrophage Escape

(2013) Miranda J. Patterson et al.   ANTIOXIDANTS & REDOX SIGNALING

Candida albicans Triggers NLRP3-Mediated Pyroptosis in Macrophages

(2013) Melanie Wellington et al.   EUKARYOTIC CELL

CX3CR1-dependent renal macrophage survival promotes Candida control and host survival

(2013) Michail S. Lionakis et al.   JOURNAL OF CLINICAL INVESTIGATION

Human Natural Killer Cells Acting as Phagocytes Against Candida albicans and Mounting an Inflammatory Response That Modulates Neutrophil Antifungal Activity

(2013) Jessica Voigt et al.   JOURNAL OF INFECTIOUS DISEASES

Inflammatory Monocytes Mediate Early and Organ-Specific Innate Defense During Systemic Candidiasis

(2013) Lisa Y. Ngo et al.   JOURNAL OF INFECTIOUS DISEASES

Candida albicans escapes from mouse neutrophils

(2013) David Ermert et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Fungal Immune Evasion in a Model Host–Pathogen Interaction: Candida albicans Versus Macrophages

(2013) Claudia Jiménez-López et al.   PLoS Pathogens

NADPH Oxidase-Driven Phagocyte Recruitment Controls Candida albicans Filamentous Growth and Prevents Mortality

(2013) Kimberly M. Brothers et al.   PLoS Pathogens

Signalling C-Type Lectins in Antimicrobial Immunity

(2013) Rebecca A. Drummond et al.   PLoS Pathogens

Neutrophil Function: From Mechanisms to Disease

(2012) Borko Amulic et al.   Annual Review of Immunology

Cryptococcusinteractions with macrophages: evasion and manipulation of the phagosome by a fungal pathogen

(2012) Simon A. Johnston et al.   CELLULAR MICROBIOLOGY

White-Opaque Switching of Candida albicans Allows Immune Evasion in an Environment-Dependent Fashion

(2012) Christoph Sasse et al.   EUKARYOTIC CELL

Non-lytic expulsion/exocytosis of Candida albicans from macrophages

(2012) Judith M. Bain et al.   FUNGAL GENETICS AND BIOLOGY

Candida albicans infection inhibits macrophage cell division and proliferation

(2012) Leanne E. Lewis et al.   FUNGAL GENETICS AND BIOLOGY

Mincle polarizes human monocyte and neutrophil responses to Candida albicans

(2012) Dipti Vijayan et al.   IMMUNOLOGY AND CELL BIOLOGY

Interplay between Candida albicans and the Mammalian Innate Host Defense

(2012) Shih-Chin Cheng et al.   INFECTION AND IMMUNITY

Cellular Responses of Candida albicans to Phagocytosis and the Extracellular Activities of Neutrophils Are Critical to Counteract Carbohydrate Starvation, Oxidative and Nitrosative Stress

(2012) Pedro Miramón et al.   PLoS One

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Stage Specific Assessment of Candida albicans Phagocytosis by Macrophages Identifies Cell Wall Composition and Morphogenesis as Key Determinants

(2012) Leanne E. Lewis et al.   PLoS Pathogens

Agent-Based Modeling Approach of Immune Defense Against Spores of Opportunistic Human Pathogenic Fungi

(2012) Christian Tokarski et al.   Frontiers in Microbiology

Innate Antifungal Immunity: The Key Role of Phagocytes

(2011) Gordon D. Brown   Annual Review of Immunology

The contribution of mouse models to our understanding of systemic candidiasis

(2011) Edina K. Szabo et al.   FEMS MICROBIOLOGY LETTERS

The Interaction between Candida krusei and Murine Macrophages Results in Multiple Outcomes, Including Intracellular Survival and Escape from Killing

(2011) Rocío García-Rodas et al.   INFECTION AND IMMUNITY

Control and Manipulation of Pathogens with an Optical Trap for Live Cell Imaging of Intercellular Interactions

(2011) Jenny M. Tam et al.   PLoS One

Phagocytosis of Cryptococcus neoformans by, and Nonlytic Exocytosis from, Acanthamoeba castellanii

(2010) C. J. Chrisman et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Interaction of pathogenic yeasts with phagocytes: survival, persistence and escape

(2010) Katja Seider et al.   CURRENT OPINION IN MICROBIOLOGY

Recognition of Yeast by Murine Macrophages Requires Mannan but Not Glucan

(2010) Sabine Keppler-Ross et al.   EUKARYOTIC CELL

Contribution of Candida albicans Cell Wall Components to Recognition by and Escape from Murine Macrophages

(2010) C. G. J. McKenzie et al.   INFECTION AND IMMUNITY

Imaging morphogenesis of Candida albicans during infection in a live animal

(2010) Soumya Mitra et al.   JOURNAL OF BIOMEDICAL OPTICS

Cryptococci at the brain gate: break and enter or use a Trojan horse?

(2010) Arturo Casadevall   JOURNAL OF CLINICAL INVESTIGATION

Organ-Specific Innate Immune Responses in a Mouse Model of Invasive Candidiasis

(2010) Michail S. Lionakis et al.   Journal of Innate Immunity

Thioredoxin Regulates Multiple Hydrogen Peroxide-Induced Signaling Pathways in Candida albicans

(2010) A. da Silva Dantas et al.   MOLECULAR AND CELLULAR BIOLOGY

A Novel Pseudopodial Component of the Dendritic Cell Anti-Fungal Response: The Fungipod

(2010) Aaron K. Neumann et al.   PLoS Pathogens

Production of Extracellular Traps against Aspergillus fumigatus In Vitro and in Infected Lung Tissue Is Dependent on Invading Neutrophils and Influenced by Hydrophobin RodA

(2010) Sandra Bruns et al.   PLoS Pathogens

Candida albicansinternalization by host cells is mediated by a clathrin-dependent mechanism

(2009) Emilia Moreno-Ruiz et al.   CELLULAR MICROBIOLOGY

Fungal adaptation to the host environment

(2009) Bernhard Hube   CURRENT OPINION IN MICROBIOLOGY

A Multifunctional, Synthetic Gaussia princeps Luciferase Reporter for Live Imaging of Candida albicans Infections

(2009) B. Enjalbert et al.   INFECTION AND IMMUNITY

Transient assembly of F-actin by phagosomes delays phagosome fusion with lysosomes in cargo-overloaded macrophages

(2009) D. Liebl et al.   JOURNAL OF CELL SCIENCE

Surface hydrophobin prevents immune recognition of airborne fungal spores

(2009) Vishukumar Aimanianda et al.   NATURE

Neutrophil Extracellular Traps Contain Calprotectin, a Cytosolic Protein Complex Involved in Host Defense against Candida albicans

(2009) Constantin F. Urban et al.   PLoS Pathogens

Actin and Phosphoinositide Recruitment to Fully Formed Candida albicans Phagosomes in Mouse Macrophages

(2008) Sigrid E.M. Heinsbroek et al.   Journal of Innate Immunity

Candida albicanscell surface superoxide dismutases degrade host-derived reactive oxygen species to escape innate immune surveillance

(2008) Ingrid E. Frohner et al.   MOLECULAR MICROBIOLOGY

The Outcome of Phagocytic Cell Division with Infectious Cargo Depends on Single Phagosome Formation

(2008) Yong Luo et al.   PLoS One

An integrated model of the recognition of Candida albicans by the innate immune system

(2007) Mihai G. Netea et al.   NATURE REVIEWS MICROBIOLOGY