Learning the pattern of epistasis linking genotype and phenotype in a protein
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Title
Learning the pattern of epistasis linking genotype and phenotype in a protein
Authors
Keywords
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Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-09-16
DOI
10.1038/s41467-019-12130-8
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- (2018) Jay F Storz CURRENT OPINION IN STRUCTURAL BIOLOGY
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- (2017) Zachary R. Sailer et al. GENETICS
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- (2017) Thomas A Hopf et al. NATURE BIOTECHNOLOGY
- A Simple Combinatorial Codon Mutagenesis Method for Targeted Protein Engineering
- (2017) Ketaki D. Belsare et al. ACS Synthetic Biology
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- (2016) Arjun S. Raman et al. CELL
- Evolution-Based Functional Decomposition of Proteins
- (2016) Olivier Rivoire et al. PLoS Computational Biology
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- (2016) Frank J. Poelwijk et al. PLoS Computational Biology
- Evolvability as a Function of Purifying Selection in TEM-1 β-Lactamase
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- (2015) Matteo Figliuzzi et al. MOLECULAR BIOLOGY AND EVOLUTION
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- (2015) Adam C. Palmer et al. Nature Communications
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- (2015) Caitlin A. Kowalsky et al. PLoS One
- Advances in the directed evolution of proteins
- (2014) Michael D Lane et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Empirical fitness landscapes and the predictability of evolution
- (2014) J. Arjan G.M. de Visser et al. NATURE REVIEWS GENETICS
- Robust and accurate prediction of residue–residue interactions across protein interfaces using evolutionary information
- (2014) Sergey Ovchinnikov et al. eLife
- Should evolutionary geneticists worry about higher-order epistasis?
- (2013) Daniel M Weinreich et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- EPISTATIC INTERACTIONS DETERMINE THE MUTATIONAL PATHWAYS AND COEXISTENCE OF LINEAGES IN CLONALESCHERICHIA COLIPOPULATIONS
- (2013) Ram Prasad Maharjan et al. EVOLUTION
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- Genotype to Phenotype Mapping and the Fitness Landscape of the E. coli lac Promoter
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- (2013) J. I. Jimenez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The spatial architecture of protein function and adaptation
- (2012) Richard N. McLaughlin Jr et al. NATURE
- Protein structure prediction from sequence variation
- (2012) Debora S Marks et al. NATURE BIOTECHNOLOGY
- Tradeoffs and Optimality in the Evolution of Gene Regulation
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- Protein 3D Structure Computed from Evolutionary Sequence Variation
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- Direct-coupling analysis of residue coevolution captures native contacts across many protein families
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- Alternating Direction Algorithms for $\ell_1$-Problems in Compressive Sensing
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- Molecular mechanisms of epistasis within and between genes
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- Structural Characterization of Acylimine-Containing Blue and Red Chromophores in mTagBFP and TagRFP Fluorescent Proteins
- (2010) Oksana M. Subach et al. CHEMISTRY & BIOLOGY
- Charting the genetic interaction map of a cell
- (2010) Michael Costanzo et al. CURRENT OPINION IN BIOTECHNOLOGY
- Status of protein engineering for biocatalysts: how to design an industrially useful biocatalyst
- (2010) Andreas S Bommarius et al. CURRENT OPINION IN CHEMICAL BIOLOGY
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- (2009) Dmitry Shcherbo et al. BIOCHEMICAL JOURNAL
- Protein Sectors: Evolutionary Units of Three-Dimensional Structure
- (2009) Najeeb Halabi et al. CELL
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- (2008) Patrick C. Phillips NATURE REVIEWS GENETICS
- Identification of direct residue contacts in protein-protein interaction by message passing
- (2008) M. Weigt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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