Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel
Authors
Keywords
-
Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-08-20
DOI
10.1038/s41467-019-11733-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel
- (2019) Ying Yin et al. SCIENCE
- Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes
- (2019) Lejla Zubcevic et al. eLife
- Conformational plasticity in the selectivity filter of the TRPV2 ion channel
- (2018) Lejla Zubcevic et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Conformational plasticity in the selectivity filter of the TRPV2 ion channel
- (2018) Lejla Zubcevic et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structure of a TRPM2 channel in complex with Ca2+ explains unique gating regulation
- (2018) Zhe Zhang et al. eLife
- X-ray and cryo-EM structures of the mitochondrial calcium uniporter
- (2018) Chao Fan et al. NATURE
- Cryo-EM structure of a fungal mitochondrial calcium uniporter
- (2018) Nam X. Nguyen et al. NATURE
- Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters
- (2018) Rozbeh Baradaran et al. NATURE
- Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium
- (2018) Yihe Huang et al. NATURE
- Structures and gating mechanism of human TRPM2
- (2018) Longfei Wang et al. SCIENCE
- Conformational ensemble of the human TRPV3 ion channel
- (2018) Lejla Zubcevic et al. Nature Communications
- Structures of the calcium-activated, non-selective cation channel TRPM4
- (2017) Jiangtao Guo et al. NATURE
- Electron cryo-microscopy structure of a human TRPM4 channel
- (2017) Paige A. Winkler et al. NATURE
- Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3
- (2017) Marscha Hirschi et al. NATURE
- MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
- (2017) Shawn Q Zheng et al. NATURE METHODS
- cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
- (2017) Ali Punjani et al. NATURE METHODS
- Structure of the cold- and menthol-sensing ion channel TRPM8
- (2017) Ying Yin et al. SCIENCE
- Structure of the human TRPM4 ion channel in a lipid nanodisc
- (2017) Henriette E. Autzen et al. SCIENCE
- Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating
- (2016) Doreen Matthies et al. CELL
- Gctf: Real-time CTF determination and correction
- (2016) Kai Zhang JOURNAL OF STRUCTURAL BIOLOGY
- The TRPM2 ion channel is required for sensitivity to warmth
- (2016) Chun-Hsiang Tan et al. NATURE
- Cryo-electron microscopy structure of the TRPV2 ion channel
- (2016) Lejla Zubcevic et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia
- (2016) K. Song et al. SCIENCE
- Cryo-electron microscopy structure of the TRPV2 ion channel
- (2016) Lejla Zubcevic et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity
- (2016) Iordan Iordanov et al. eLife
- Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2
- (2016) Dari Kimanius et al. eLife
- Ruling out pyridine dinucleotides as true TRPM2 channel activators reveals novel direct agonist ADP-ribose-2′-phosphate
- (2015) Balázs Tóth et al. JOURNAL OF GENERAL PHYSIOLOGY
- CTFFIND4: Fast and accurate defocus estimation from electron micrographs
- (2015) Alexis Rohou et al. JOURNAL OF STRUCTURAL BIOLOGY
- High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy
- (2013) Shaoxia Chen et al. ULTRAMICROSCOPY
- Prevention of overfitting in cryo-EM structure determination
- (2012) Sjors H W Scheres et al. NATURE METHODS
- Pore collapse underlies irreversible inactivation of TRPM2 cation channel currents
- (2012) B. Toth et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TRPM2 modulates insulin secretion in pancreatic β-cells
- (2011) Kunitoshi Uchida et al. Islets
- Lack of TRPM2 Impaired Insulin Secretion and Glucose Metabolisms in Mice
- (2010) K. Uchida et al. DIABETES
- Identification of Direct and Indirect Effectors of the Transient Receptor Potential Melastatin 2 (TRPM2) Cation Channel
- (2010) Balázs Tóth et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- electronic Ligand Builder and Optimization Workbench(eLBOW): a tool for ligand coordinate and restraint generation
- (2009) Nigel W. Moriarty et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Four Ca2+Ions Activate TRPM2 Channels by Binding in Deep Crevices near the Pore but Intracellularly of the Gate
- (2009) László Csanády et al. JOURNAL OF GENERAL PHYSIOLOGY
- Appion: An integrated, database-driven pipeline to facilitate EM image processing
- (2009) Gabriel C. Lander et al. JOURNAL OF STRUCTURAL BIOLOGY
- DoG Picker and TiltPicker: Software tools to facilitate particle selection in single particle electron microscopy
- (2009) N.R. Voss et al. JOURNAL OF STRUCTURAL BIOLOGY
- TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration
- (2008) Shinichiro Yamamoto et al. NATURE MEDICINE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started