Physiologically relevant reconstitution of iron-sulfur cluster biosynthesis uncovers persulfide-processing functions of ferredoxin-2 and frataxin
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Physiologically relevant reconstitution of iron-sulfur cluster biosynthesis uncovers persulfide-processing functions of ferredoxin-2 and frataxin
Authors
Keywords
-
Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-08-08
DOI
10.1038/s41467-019-11470-9
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Zinc(II) binding on human wild-type ISCU and Met140 variants modulates NFS1 desulfurase activity
- (2018) Nicholas G. Fox et al. BIOCHIMIE
- Iron–sulfur clusters: from metals through mitochondria biogenesis to disease
- (2018) Mauricio Cardenas-Rodriguez et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Roles and maturation of iron–sulfur proteins in plastids
- (2018) Jonathan Przybyla-Toscano et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- Protein networks in the maturation of human iron–sulfur proteins
- (2018) Simone Ciofi-Baffoni et al. Metallomics
- Iron–sulfur cluster biogenesis and trafficking in mitochondria
- (2017) Joseph J. Braymer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Biogenesis and functions of mammalian iron-sulfur proteins in the regulation of iron homeostasis and pivotal metabolic pathways
- (2017) Tracey A. Rouault et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- In vitro characterization of a novel Isu homologue from Drosophila melanogaster for de novo FeS-cluster formation
- (2017) Stephen P. Dzul et al. Metallomics
- NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis
- (2017) Samantha W. Alvarez et al. NATURE
- Structure of human Fe–S assembly subcomplex reveals unexpected cysteine desulfurase architecture and acyl-ACP–ISD11 interactions
- (2017) Seth A. Cory et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis
- (2017) Sven-A. Freibert et al. Nature Communications
- ISCA1 is essential for mitochondrial Fe4S4 biogenesis in vivo
- (2017) Lena Kristina Beilschmidt et al. Nature Communications
- Structure and functional dynamics of the mitochondrial Fe/S cluster synthesis complex
- (2017) Michal T. Boniecki et al. Nature Communications
- The Human Iron–Sulfur Assembly Complex Catalyzes the Synthesis of [2Fe-2S] Clusters on ISCU2 That Can Be Transferred to Acceptor Molecules
- (2015) Nicholas G. Fox et al. BIOCHEMISTRY
- Emerging critical roles of Fe–S clusters in DNA replication and repair
- (2015) Jill O. Fuss et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Iron loading site on the Fe–S cluster assembly scaffold protein is distinct from the active site
- (2015) Andria V. Rodrigues et al. BIOMETALS
- SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery
- (2015) Neetu Saxena et al. JNCI-Journal of the National Cancer Institute
- The iron-binding CyaY and IscX proteins assist the ISC-catalyzed Fe-S biogenesis inEscherichia coli
- (2015) Béatrice Roche et al. MOLECULAR MICROBIOLOGY
- Mammalian frataxin directly enhances sulfur transfer of NFS1 persulfide to both ISCU and free thiols
- (2015) Aubérie Parent et al. Nature Communications
- SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery
- (2015) Neetu Saxena et al. JNCI-Journal of the National Cancer Institute
- Frataxin-bypassing Isu1: characterization of the bypass activity in cells and mitochondria
- (2014) Heeyong Yoon et al. BIOCHEMICAL JOURNAL
- Human Frataxin Activates Fe–S Cluster Biosynthesis by Facilitating Sulfur Transfer Chemistry
- (2014) Jennifer Bridwell-Rabb et al. BIOCHEMISTRY
- Mitochondrial iron–sulfur protein biogenesis and human disease
- (2014) Oliver Stehling et al. BIOCHIMIE
- Redesigning the Blue Copper Azurin into a Redox-Active Mononuclear Nonheme Iron Protein: Preparation and Study of Fe(II)-M121E Azurin
- (2014) Jing Liu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The role of zinc in the stability of the marginally stable IscU scaffold protein
- (2014) Clara Iannuzzi et al. PROTEIN SCIENCE
- Functional reconstitution of mitochondrial Fe/S cluster synthesis on Isu1 reveals the involvement of ferredoxin
- (2014) Holger Webert et al. Nature Communications
- Dysregulation of cellular iron metabolism in Friedreich ataxia: from primary iron-sulfur cluster deficit to mitochondrial iron accumulation
- (2014) Alain Martelli et al. Frontiers in Pharmacology
- Fe-S Cluster Biogenesis in Gram-Positive Bacteria: SufU Is a Zinc-Dependent Sulfur Transfer Protein
- (2013) Bruna P. Selbach et al. BIOCHEMISTRY
- Iron/sulfur proteins biogenesis in prokaryotes: Formation, regulation and diversity
- (2013) Béatrice Roche et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Frataxin Directly Stimulates Mitochondrial Cysteine Desulfurase by Exposing Substrate-binding Sites, and a Mutant Fe-S Cluster Scaffold Protein with Frataxin-bypassing Ability Acts Similarly
- (2013) Alok Pandey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fe-S Cluster Biosynthesis Controls Uptake of Aminoglycosides in a ROS-Less Death Pathway
- (2013) B. Ezraty et al. SCIENCE
- (IscS-IscU)2Complex Structures Provide Insights into Fe2S2Biogenesis and Transfer
- (2012) Elodie N. Marinoni et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The rotavirus nonstructural protein NSP5 coordinates a [2Fe-2S] iron-sulfur cluster that modulates interaction to RNA
- (2012) Davy Martin et al. FASEB JOURNAL
- Azurin as a Protein Scaffold for a Low-coordinate Nonheme Iron Site with a Small-molecule Binding Pocket
- (2012) Matthew P. McLaughlin et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Mammalian Frataxin Controls Sulfur Production and Iron Entry during de Novo Fe4S4 Cluster Assembly
- (2012) Florent Colin et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Facilitated Transfer of IscU–[2Fe2S] Clusters by Chaperone-Mediated Ligand Exchange
- (2011) Francesco Bonomi et al. BIOCHEMISTRY
- Specialized Function of Yeast Isa1 and Isa2 Proteins in the Maturation of Mitochondrial [4Fe-4S] Proteins
- (2011) Ulrich Mühlenhoff et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Role of CyaY in Iron Sulfur Cluster Assembly on the E. coli IscU Scaffold Protein
- (2011) Clara Iannuzzi et al. PLoS One
- Human Frataxin Is an Allosteric Switch That Activates the Fe−S Cluster Biosynthetic Complex
- (2010) Chi-Lin Tsai et al. BIOCHEMISTRY
- Evidence that yeast frataxin is not an iron storage protein in vivo
- (2010) Alexandra Seguin et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis
- (2010) A. D. Sheftel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure and Dynamics of the Iron−Sulfur Cluster Assembly Scaffold Protein IscU and Its Interaction with the Cochaperone HscB
- (2009) Jin Hae Kim et al. BIOCHEMISTRY
- Deficiency in frataxin homologue YFH1 in the yeast Pichia guilliermondii leads to missregulation of iron acquisition and riboflavin biosynthesis and affects sulfate assimilation
- (2009) Yuriy V. Pynyaha et al. BIOMETALS
- Bacterial frataxin CyaY is the gatekeeper of iron-sulfur cluster formation catalyzed by IscS
- (2009) Salvatore Adinolfi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The Asymmetric Trimeric Architecture of [2Fe–2S] IscU: Implications for Its Scaffolding during Iron–Sulfur Cluster Biosynthesis
- (2008) Yoshimitsu Shimomura et al. JOURNAL OF MOLECULAR BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started