ISCA1 is essential for mitochondrial Fe4S4 biogenesis in vivo

Mutation of the iron-sulfur cluster assembly gene IBA57 causes fatal infantile leukodystrophy

(2015) François-Guillaume Debray et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Mammalian frataxin directly enhances sulfur transfer of NFS1 persulfide to both ISCU and free thiols

(2015) Aubérie Parent et al.   Nature Communications

High-Spin Ferric Ions in Saccharomyces cerevisiae Vacuoles Are Reduced to the Ferrous State during Adenine-Precursor Detoxification

(2014) Jinkyu Park et al.   BIOCHEMISTRY

Human Frataxin Activates Fe–S Cluster Biosynthesis by Facilitating Sulfur Transfer Chemistry

(2014) Jennifer Bridwell-Rabb et al.   BIOCHEMISTRY

Mammalian Fe–S cluster biogenesis and its implication in disease

(2014) Lena K. Beilschmidt et al.   BIOCHIMIE

A Conserved Mitochondrial ATP-binding Cassette Transporter Exports Glutathione Polysulfide for Cytosolic Metal Cofactor Assembly

(2014) Theresia A. Schaedler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ISCA2mutation causes infantile neurodegenerative mitochondrial disorder

(2014) Zuhair N Al-Hassnan et al.   JOURNAL OF MEDICAL GENETICS

Formation of [4Fe-4S] Clusters in the Mitochondrial Iron–Sulfur Cluster Assembly Machinery

(2014) Diego Brancaccio et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

[2Fe-2S] cluster transfer in iron-sulfur protein biogenesis

(2014) L. Banci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutation of the iron-sulfur cluster assembly gene IBA57 causes severe myopathy and encephalopathy

(2013) Nikhita Ajit Bolar et al.   HUMAN MOLECULAR GENETICS

DDIT4/REDD1/RTP801 Is a Novel Negative Regulator of Schwann Cell Myelination

(2013) R. Noseda et al.   JOURNAL OF NEUROSCIENCE

[2Fe-2S]-Ferredoxin Binds Directly to Cysteine Desulfurase and Supplies an Electron for Iron–Sulfur Cluster Assembly but Is Displaced by the Scaffold Protein or Bacterial Frataxin

(2013) Jin Hae Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biophysical Investigation of the Ironome of Human Jurkat Cells and Mitochondria

(2012) Nema D. Jhurry et al.   BIOCHEMISTRY

Spectroscopic and Functional Characterization of Iron–Sulfur Cluster-Bound Forms of Azotobacter vinelandiiNifIscA

(2012) Daphne T. Mapolelo et al.   BIOCHEMISTRY

Characterization of the [2Fe-2S] Cluster of Escherichia coli Transcription Factor IscR

(2012) Angela S. Fleischhacker et al.   BIOCHEMISTRY

Mammalian Frataxin Controls Sulfur Production and Iron Entry during de Novo Fe4S4 Cluster Assembly

(2012) Florent Colin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The human mitochondrial ISCA1, ISCA2, and IBA57 proteins are required for [4Fe-4S] protein maturation

(2012) Alex D. Sheftel et al.   MOLECULAR BIOLOGY OF THE CELL

Mutations in Iron-Sulfur Cluster Scaffold Genes NFU1 and BOLA3 Cause a Fatal Deficiency of Multiple Respiratory Chain and 2-Oxoacid Dehydrogenase Enzymes

(2011) Jessie M. Cameron et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Fatal Mitochondrial Disease Is Associated with Defective NFU1 Function in the Maturation of a Subset of Mitochondrial Fe-S Proteins

(2011) Aleix Navarro-Sastre et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Reversible (De)protonation-Induced Valence Inversion in Mixed-Valent Diiron(II,III) Complexes

(2011) Eric Gouré et al.   INORGANIC CHEMISTRY

Specialized Function of Yeast Isa1 and Isa2 Proteins in the Maturation of Mitochondrial [4Fe-4S] Proteins

(2011) Ulrich Mühlenhoff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian Frataxin: An Essential Function for Cellular Viability through an Interaction with a Preformed ISCU/NFS1/ISD11 Iron-Sulfur Assembly Complex

(2011) Stéphane Schmucker et al.   PLoS One

Human Frataxin Is an Allosteric Switch That Activates the Fe−S Cluster Biosynthetic Complex

(2010) Chi-Lin Tsai et al.   BIOCHEMISTRY

IscA/SufA paralogues are required for the [4Fe-4S] cluster assembly in enzymes of multiple physiological pathways inEscherichia coliunder aerobic growth conditions

(2009) Guoqiang Tan et al.   BIOCHEMICAL JOURNAL

The Iron−Sulfur Cluster of Pyruvate Formate-Lyase Activating Enzyme in Whole Cells: Cluster Interconversion and a Valence-Localized [4Fe-4S]2+State

(2009) Jian Yang et al.   BIOCHEMISTRY

Frataxin deficiency causes upregulation of mitochondrial Lon and ClpP proteases and severe loss of mitochondrial Fe-S proteins

(2009) Blanche Guillon et al.   FEBS Journal

Isoprenoid Biosynthesis via the MEP Pathway:In VivoMössbauer Spectroscopy Identifies a [4Fe-4S]2+Center with Unusual Coordination Sphere in the LytB Protein

(2009) Myriam Seemann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

NativeEscherichia coliSufA, Coexpressed with SufBCDSE, Purifies as a [2Fe−2S] Protein and Acts as an Fe−S Transporter to Fe−S Target Enzymes

(2009) Vibha Gupta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Function and biogenesis of iron–sulphur proteins

(2009) Roland Lill   NATURE

Iron-Sulfur (Fe/S) Protein Biogenesis: Phylogenomic and Genetic Studies of A-Type Carriers

(2009) Daniel Vinella et al.   PLoS Genetics

Complementary roles of SufA and IscA in the biogenesis of iron–sulfur clusters inEscherichia coli

(2008) Jianxin Lu et al.   BIOCHEMICAL JOURNAL

Importance of the Maintenance Pathway in the Regulation of the Activity ofEscherichia coliRibonucleotide Reductase†

(2008) Daniela Hristova et al.   BIOCHEMISTRY

EPR and Mössbauer Spectroscopy of Intact Mitochondria Isolated from Yah1p-DepletedSaccharomyces cerevisiae†

(2008) Ren Miao et al.   BIOCHEMISTRY

The in vivo mitochondrial two-step maturation of human frataxin

(2008) Stéphane Schmucker et al.   HUMAN MOLECULAR GENETICS

NfuA, a New Factor Required for Maturing Fe/S Proteins inEscherichia coliunder Oxidative Stress and Iron Starvation Conditions

(2008) Sandra Angelini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Proposed Role for theAzotobacter vinelandiiNfuA Protein as an Intermediate Iron-Sulfur Cluster Carrier

(2008) Sibali Bandyopadhyay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY