Extracellular IL-37 promotes osteogenic differentiation of human bone marrow mesenchymal stem cells via activation of the PI3K/AKT signaling pathway

Sal B targets TAZ to facilitate osteogenesis and reduce adipogenesis through MEK‐ERK pathway

(2019) Na Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Functionalization of Silk Fibroin Electrospun Scaffolds via BMSC Affinity Peptide Grafting through Oxidative Self-Polymerization of Dopamine for Bone Regeneration

(2019) Jiannan Wu et al.   ACS Applied Materials & Interfaces

Ca v 1.2 regulates osteogenesis of bone marrow‐derived mesenchymal stem cells via canonical Wnt pathway in age‐related osteoporosis

(2019) Dongdong Fei et al.   AGING CELL

Osteogenesis activity of isocoumarin a through the activation of the PI3K-Akt/Erk cascade-activated BMP/RUNX2 signaling pathway

(2019) Min-zhen Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

An asymmetric chitosan scaffold for tendon tissue engineering: In vitro and in vivo evaluation with rat tendon stem/progenitor cells

(2018) Erman Chen et al.   Acta Biomaterialia

Stimulation of calvarial bone healing with human bone marrow stromal cells versus inhibition with adipose-tissue stromal cells on nanostructured β-TCP-collagen

(2018) Friederike Bothe et al.   Acta Biomaterialia

IL-8 Enhances Therapeutic Effects of BMSCs on Bone Regeneration via CXCR2-Mediated PI3k/Akt Signaling Pathway

(2018) Aijun Yang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Concentration-dependent, dual roles of IL-10 in the osteogenesis of human BMSCs via P38/MAPK and NF-κB signaling pathways

(2018) Erman Chen et al.   FASEB JOURNAL

IGFBP7 regulates the osteogenic differentiation of bone marrow–derived mesenchymal stem cells via Wnt/β-catenin signaling pathway

(2018) Wei Zhang et al.   FASEB JOURNAL

Synergistic effect of strontium, bioactive glass and nano-hydroxyapatite promotes bone regeneration of critical-sized radial bone defects

(2018) Ahmad Oryan et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Repair of Calvarial Bone Defect Using Jarid1a-Knockdown Bone Mesenchymal Stem Cells in Rats

(2018) Yuan Deng et al.   TISSUE ENGINEERING PART A

Alendronate delivery on amino modified mesoporous bioactive glass scaffolds to enhance bone regeneration in osteoporosis rats

(2018) Xiao Wang et al.   Artificial Cells Nanomedicine and Biotechnology

Anti-Allergic Inflammatory Activity of Interleukin-37 Is Mediated by Novel Signaling Cascades in Human Eosinophils

(2018) Jing Zhu et al.   Frontiers in Immunology

Layer-by-layer nanofiber-enabled engineering of biomimetic periosteum for bone repair and reconstruction

(2018) Tao Wang et al.   BIOMATERIALS

Treatment of posttraumatic bone defects of the forearm with vascularized fibular grafts. Follow up after fourteen years

(2018) P. Cano-Luís et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Knockdown of FOXA2 enhances the osteogenic differentiation of bone marrow-derived mesenchymal stem cells partly via activation of the ERK signalling pathway

(2018) Chenyi Ye et al.   Cell Death & Disease

IL-33 guides osteogenesis and increases proliferation and pluripotency marker expression in dental stem cells

(2018) Tamara Kukolj et al.   CELL PROLIFERATION

Interleukin-37 Ameliorates Coxsackievirus B3-induced Viral Myocarditis by Modulating the Th17/Regulatory T cell Immune Response

(2017) Bang An et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

IL-37 induces autophagy in hepatocellular carcinoma cells by inhibiting the PI3K/AKT/mTOR pathway

(2017) Ting-Ting Li et al.   MOLECULAR IMMUNOLOGY

Knockdown of SIRT7 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly via activation of the Wnt/β-catenin signaling pathway

(2017) Erman E M Chen et al.   Cell Death & Disease

Zero-order controlled release of BMP2-derived peptide P24 from the chitosan scaffold by chemical grafting modification technique for promotion of osteogenesis in vitro and enhancement of bone repair in vivo

(2017) Yan Chen et al.   Theranostics

The Impact of Conventional and Biological Disease Modifying Antirheumatic Drugs on Bone Biology. Rheumatoid Arthritis as a Case Study

(2016) Sofia Carvalho Barreira et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

IL-37 inhibits lipopolysaccharide-induced osteoclast formation and bone resorption in vivo

(2016) Jafari Saeed et al.   IMMUNOLOGY LETTERS

Gremlin2 Suppression Increases the BMP-2-Induced Osteogenesis of Human Bone Marrow-Derived Mesenchymal Stem Cells Via the BMP-2/Smad/Runx2 Signaling Pathway

(2016) Cheng-Long Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Microenvironmental Views on Mesenchymal Stem Cell Differentiation in Aging

(2016) B.D. Sui et al.   JOURNAL OF DENTAL RESEARCH

A protective role of IL-37 in cancer: a new hope for cancer patients

(2016) Ayoub Abulkhir et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Beneficial effects of IL-37 after spinal cord injury in mice

(2016) Marina Coll-Miró et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation

(2016) Giulio Cavalli et al.   RHEUMATOLOGY

HMGB1 promotes the secretion of multiple cytokines and potentiates the osteogenic differentiation of mesenchymal stem cells through the Ras/MAPK signaling pathway

(2016) Lin Feng et al.   Experimental and Therapeutic Medicine

Overexpression of HSPA1A enhances the osteogenic differentiation of bone marrow mesenchymal stem cells via activation of the Wnt/β-catenin signaling pathway

(2016) Wei Zhang et al.   Scientific Reports

Magnetic Nanocomposite Hydrogel for Potential Cartilage Tissue Engineering: Synthesis, Characterization, and Cytocompatibility with Bone Marrow Derived Mesenchymal Stem Cells

(2015) Naiyin Zhang et al.   ACS Applied Materials & Interfaces

Elevated serum levels of Interleukin-37 are associated with inflammatory cytokines and disease activity in rheumatoid arthritis

(2015) Libin Yang et al.   APMIS

IL-37 Is a Novel Proangiogenic Factor of Developmental and Pathological AngiogenesisSignificance

(2015) Tianshu Yang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mechano-growth factor accelerates the proliferation and osteogenic differentiation of rabbit mesenchymal stem cells through the PI3K/AKT pathway

(2015) Yanxiang Tong et al.   BMC BIOCHEMISTRY

Elevated serum and synovial fluid levels of interleukin-37 in patients with rheumatoid arthritis: Attenuated the production of inflammatory cytokines

(2015) Liping Xia et al.   CYTOKINE

Plasma Interleukin-37 Is Elevated in Patients with Rheumatoid Arthritis: Its Correlation with Disease Activity and Th1/Th2/Th17-Related Cytokines

(2015) Ting Xia et al.   DISEASE MARKERS

Interleukin-37 is increased in ankylosing spondylitis patients and associated with disease activity

(2015) Bingni Chen et al.   Journal of Translational Medicine

IL-37 mediates the antitumor activity in renal cell carcinoma

(2015) Yazhuo Jiang et al.   MEDICAL ONCOLOGY

COMP-angiopoietin 1 increases proliferation, differentiation, and migration of stem-like cells through Tie-2-mediated activation of p38 MAPK and PI3K/Akt signal transduction pathways

(2014) Sung-Ho Kook et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The osteoregenerative effects of platelet-derived growth factor BB cotransplanted with mesenchymal stem cells, loaded on freeze-dried mineral bone block: A pilot study in dog mandible

(2014) Arash Khojasteh et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Bradykinin Regulates Osteoblast Differentiation by Akt/ERK/NFκB Signaling Axis

(2014) Swati Srivastava et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses

(2014) A.-M. Bulau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-37 protects against obesity-induced inflammation and insulin resistance

(2014) Dov B. Ballak et al.   Nature Communications

TNFα and IL-1β influence the differentiation and migration of murine MSCs independently of the NF-κB pathway

(2014) Catherine B Sullivan et al.   Stem Cell Research & Therapy

IL-6 is produced by adipose-derived stromal cells and promotes osteogenesis

(2013) Jeong-Eun Huh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Treatment of Failed Allograft Prosthesis Composites Used for Hip Arthroplasty in the Setting of Severe Proximal Femoral Bone Defects

(2013) Amir Sternheim et al.   JOURNAL OF ARTHROPLASTY

Bone marrow mesenchymal stem cells, platelet-rich plasma and nanohydroxyapatite-type I collagen beads were integral parts of biomimetic bone substitutes for bone regeneration

(2012) Bo-Nian Lin et al.   Journal of Tissue Engineering and Regenerative Medicine

IL-37 is a fundamental inhibitor of innate immunity

(2010) Marcel F Nold et al.   NATURE IMMUNOLOGY

Risk of osteoporotic fracture in a large population-based cohort of patients with rheumatoid arthritis

(2010) Seo Young Kim et al.   ARTHRITIS RESEARCH & THERAPY

The recruitment of two consecutive and different waves of host stem/progenitor cells during the development of tissue-engineered bone in a murine model

(2009) Roberta Tasso et al.   BIOMATERIALS

The development of tissue-engineered bone of different origin through endochondral and intramembranous ossification following the implantation of mesenchymal stem cells and osteoblasts in a murine model

(2009) Federico Tortelli et al.   BIOMATERIALS

Akt promotes BMP2-mediated osteoblast differentiation and bone development

(2009) A. Mukherjee et al.   JOURNAL OF CELL SCIENCE

The PI3K pathway regulates endochondral bone growth through control of hypertrophic chondrocyte differentiation

(2008) Veronica Ulici et al.   BMC DEVELOPMENTAL BIOLOGY