Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses

The IL-1 Family Member 7b Translocates to the Nucleus and Down-Regulates Proinflammatory Cytokines

(2014) S. Sharma et al.   JOURNAL OF IMMUNOLOGY

Nontypeable Haemophilus Influenzae Infection Upregulates the NLRP3 Inflammasome and Leads to Caspase-1-Dependent Secretion of Interleukin-1β — A Possible Pathway of Exacerbations in COPD

(2013) Johannes Rotta detto Loria et al.   PLoS One

NLRP1 haplotypes associated with vitiligo and autoimmunity increase interleukin-1  processing via the NLRP1 inflammasome

(2013) C. B. Levandowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interleukin-37 reduces liver inflammatory injury via effects on hepatocytes and non-parenchymal cells

(2012) Nozomu Sakai et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

Comparison of non-crystalline silica nanoparticles in IL-1β release from macrophages

(2012) Wiggo J Sandberg et al.   Particle and Fibre Toxicology

Interleukin-36 (IL-36) Ligands Require Processing for Full Agonist (IL-36α, IL-36β, and IL-36γ) or Antagonist (IL-36Ra) Activity

(2011) Jennifer E. Towne et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interleukin 37 expression protects mice from colitis

(2011) E. N. McNamee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Asian sand dust enhances murine lung inflammation caused by Klebsiella pneumoniae

(2011) Miao He et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

IL-37 is a fundamental inhibitor of innate immunity

(2010) Marcel F Nold et al.   NATURE IMMUNOLOGY

Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

(2010) Kristiina Rajamäki et al.   PLoS One

Differential requirement for the activation of the inflammasome for processing and release of IL-1  in monocytes and macrophages

(2008) M. G. Netea et al.   BLOOD

Active Caspase-1 Is a Regulator of Unconventional Protein Secretion

(2008) Martin Keller et al.   CELL

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY