TREM-1 Protects HIV-1-Infected Macrophages from Apoptosis through Maintenance of Mitochondrial Function

HIV-1 reservoirs in urethral macrophages of patients under suppressive antiretroviral therapy

(2019) Yonatan Ganor et al.   Nature Microbiology

Inhibition of the lncRNA SAF drives activation of apoptotic effector caspases in HIV-1–infected human macrophages

(2019) Saikat Boliar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV and HCV augments inflammatory responses through increased TREM-1 expression and signaling in Kupffer and Myeloid cells

(2019) Jinhee Hyun et al.   PLoS Pathogens

Resistance of HIV-infected macrophages to CD8+ T lymphocyte–mediated killing drives activation of the immune system

(2018) Kiera L. Clayton et al.   NATURE IMMUNOLOGY

Determination of system level alterations in host transcriptome due to Zika virus (ZIKV) Infection in retinal pigment epithelium

(2018) Pawan Kumar Singh et al.   Scientific Reports

SMAC Mimetics Induce Autophagy-Dependent Apoptosis of HIV-1-Infected Resting Memory CD4+ T Cells

(2018) Grant R. Campbell et al.   Cell Host & Microbe

HIV persistence in tissue macrophages of humanized myeloid-only mice during antiretroviral therapy

(2017) Jenna B Honeycutt et al.   NATURE MEDICINE

Human Primary Macrophages Derived In Vitro from Circulating Monocytes Comprise Adherent and Non-Adherent Subsets with Differential Expression of Siglec-1 and CD4 and Permissiveness to HIV-1 Infection

(2017) Ousman Jobe et al.   Frontiers in Immunology

HIV-related proteins prolong macrophage survival through induction of Triggering receptor expressed on myeloid cells-1

(2017) Zhihong Yuan et al.   Scientific Reports

HIV-infected macrophages and microglia that survive acute infection become viral reservoirs by a mechanism involving Bim

(2017) Paul Castellano et al.   Scientific Reports

Macrophages sustain HIV replication in vivo independently of T cells

(2016) Jenna B. Honeycutt et al.   JOURNAL OF CLINICAL INVESTIGATION

Serum sTREM-1 level is quite higher in Crimean Congo Hemorrhagic Fever, a viral infection

(2016) Fatma Aybala Altay et al.   JOURNAL OF MEDICAL VIROLOGY

HIV-1 Eradication: Early Trials (and Tribulations)

(2016) Adam M. Spivak et al.   TRENDS IN MOLECULAR MEDICINE

The Effect of Latency Reversal Agents on Primary CD8 + T Cells: Implications for Shock and Kill Strategies for Human Immunodeficiency Virus Eradication

(2016) Victoria E. Walker-Sperling et al.   EBioMedicine

Attenuated viral hepatitis in Trem1−/− mice is associated with reduced inflammatory activity of neutrophils

(2016) Jan-Hendrik Kozik et al.   Scientific Reports

Ex vivo analysis identifies effective HIV-1 latency–reversing drug combinations

(2015) Gregory M. Laird et al.   JOURNAL OF CLINICAL INVESTIGATION

Effect of cytokines on Siglec-1 and HIV-1 entry in monocyte-derived macrophages: the importance of HIV-1 envelope V1V2 region

(2015) O. Jobe et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Extracellular Regulated Kinase Phosphorylates Mitofusin 1 to Control Mitochondrial Morphology and Apoptosis

(2015) Aswin Pyakurel et al.   MOLECULAR CELL

Eradication of HIV-1 from the Macrophage Reservoir: An Uncertain Goal?

(2015) Wasim Abbas et al.   Viruses-Basel

Triggering receptor expressed on myeloid cells receptor family modulators: a patent review

(2014) Christopher J Pelham et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

TREM-1 modulation during early stages of dengue virus infection

(2014) J.A. Ruiz-Pacheco et al.   IMMUNOLOGY LETTERS

Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1)-mediated Bcl-2 Induction Prolongs Macrophage Survival

(2014) Zhihong Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo

(2014) C Korin Bullen et al.   NATURE MEDICINE

Blockade of BFA-mediated apoptosis in macrophages by the HIV-1 Nef protein

(2014) W Abbas et al.   Cell Death & Disease

Plasma membrane signaling in HIV-1 infection

(2013) Wasim Abbas et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The Presence of HIV-1 Tat Protein Second Exon Delays Fas Protein-mediated Apoptosis in CD4+T Lymphocytes

(2013) María Rosa López-Huertas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-Multiplicity HIV-1 Infection and Neutralizing Antibody Evasion Mediated by the Macrophage-T Cell Virological Synapse

(2013) C. J. A. Duncan et al.   JOURNAL OF VIROLOGY

Modulation of Cytokine Release and Gene Expression by the Immunosuppressive Domain of gp41 of HIV-1

(2013) Joachim Denner et al.   PLoS One

Overcoming pharmacologic sanctuaries

(2013) Theodore J. Cory et al.   Current Opinion in HIV and AIDS

A Systems Biology Approach Reveals that Tissue Tropism to West Nile Virus Is Regulated by Antiviral Genes and Innate Immune Cellular Processes

(2013) Mehul S. Suthar et al.   PLoS Pathogens

Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation

(2012) Liang Shan et al.   IMMUNITY

Stress-Induced Phosphorylation and Proteasomal Degradation of Mitofusin 2 Facilitates Mitochondrial Fragmentation and Apoptosis

(2012) Guillaume P. Leboucher et al.   MOLECULAR CELL

Vitamin D Inhibits Human Immunodeficiency Virus Type 1 and Mycobacterium tuberculosis Infection in Macrophages through the Induction of Autophagy

(2012) Grant R. Campbell et al.   PLoS Pathogens

Proportion statistics to detect differentially expressed genes: a comparison with log-ratio statistics

(2011) Tracy L Bergemann et al.   BMC BIOINFORMATICS

Differential Induction of Rat Neuronal Excitotoxic Cell Death by Human Immunodeficiency Virus Type 1 Clade B and C Tat Proteins

(2010) Grant R. Campbell et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Human Fatal Zaire Ebola Virus Infection Is Associated with an Aberrant Innate Immunity and with Massive Lymphocyte Apoptosis

(2010) Nadia Wauquier et al.   PLoS Neglected Tropical Diseases