Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

(2019) Mengzhen Liu et al.   NATURE GENETICS

Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis

(2019) Simon Haworth et al.   Nature Communications

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

(2019) David M. Howard et al.   NATURE NEUROSCIENCE

Robust research needs many lines of evidence

(2018) Marcus R. Munafò et al.   NATURE

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

(2018) Naomi R. Wray et al.   NATURE GENETICS

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

(2018) Antonio F. Pardiñas et al.   NATURE GENETICS

The MR-Base platform supports systematic causal inference across the human phenome

(2018) Gibran Hemani et al.   eLife

Association of Combined Patterns of Tobacco and Cannabis Use in Adolescence With Psychotic Experiences

(2018) Hannah J. Jones et al.   JAMA Psychiatry

OUP accepted manuscript

(2018)   AMERICAN JOURNAL OF EPIDEMIOLOGY

Evidence of a Causal Relationship Between Smoking Tobacco and Schizophrenia Spectrum Disorders

(2018) James G. Scott et al.   Frontiers in Psychiatry

Collider scope: when selection bias can substantially influence observed associations

(2017) Marcus R Munafò et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Robust inference in summary data Mendelian randomization via the zero modal pleiotropy assumption

(2017) Fernando Pires Hartwig et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Orienting the causal relationship between imprecisely measured traits using GWAS summary data

(2017) Gibran Hemani et al.   PLoS Genetics

Genetic correlation between smoking behaviors and schizophrenia

(2017) Sarah M. Hartz et al.   SCHIZOPHRENIA RESEARCH

Investigating causality in associations between smoking initiation and schizophrenia using Mendelian randomization

(2017) Suzanne H. Gage et al.   Scientific Reports

Systematic Review and Meta-Analysis: Dose-Response Relationship of Selective Serotonin Reuptake Inhibitors in Major Depressive Disorder

(2016) Ewgeni Jakubovski et al.   AMERICAN JOURNAL OF PSYCHIATRY

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

(2016) Jack Bowden et al.   GENETIC EPIDEMIOLOGY

Smoking and Schizophrenia in Population Cohorts of Swedish Women and Men: A Prospective Co-Relative Control Study

(2015) Kenneth S. Kendler et al.   AMERICAN JOURNAL OF PSYCHIATRY

Associations between cigarette smoking and cannabis dependence: A longitudinal study of young cannabis users in the United Kingdom

(2015) Chandni Hindocha et al.   DRUG AND ALCOHOL DEPENDENCE

Using published data in Mendelian randomization: a blueprint for efficient identification of causal risk factors

(2015) Stephen Burgess et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Tobacco smoking is causally associated with antipsychotic medication use and schizophrenia, but not with antidepressant medication use or depression

(2015) M. K. Wium-Andersen et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Glutamate and dopamine in schizophrenia: An update for the 21st century

(2015) Oliver Howes et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Efficient Bayesian mixed-model analysis increases association power in large cohorts

(2015) Po-Ru Loh et al.   NATURE GENETICS

The association between smoking and depression from adolescence to adulthood

(2014) Tore Tjora et al.   ADDICTION

Trends in Smoking Among Adults With Mental Illness and Association Between Mental Health Treatment and Smoking Cessation

(2014) Benjamin Lê Cook et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Investigating the possible causal association of smoking with depression and anxiety using Mendelian randomisation meta-analysis: the CARTA consortium

(2014) Amy E Taylor et al.   BMJ Open

Change in mental health after smoking cessation: systematic review and meta-analysis

(2014) G. Taylor et al.   BMJ-British Medical Journal

Tobacco Smoking Leads to Extensive Genome-Wide Changes in DNA Methylation

(2013) Sonja Zeilinger et al.   PLoS One

Twenty-Year Depressive Trajectories Among Older Women

(2012) Amy L. Byers et al.   ARCHIVES OF GENERAL PSYCHIATRY

Association Between Genetic Variants on Chromosome 15q25 Locus and Objective Measures of Tobacco Exposure

(2012) Marcus R. Munafò et al.   JNCI-Journal of the National Cancer Institute

A mega-analysis of genome-wide association studies for major depressive disorder

(2012)   MOLECULAR PSYCHIATRY

The causal role of smoking in anxiety and depression: a Mendelian randomization analysis of the HUNT study

(2012) J. H. Bjørngaard et al.   PSYCHOLOGICAL MEDICINE

Association of the CHRNA5-A3-B4 Gene Cluster With Heaviness of Smoking: A Meta-Analysis

(2011) Jennifer J. Ware et al.   NICOTINE & TOBACCO RESEARCH

Life Expectancy at Birth for People with Serious Mental Illness and Other Major Disorders from a Secondary Mental Health Care Case Register in London

(2011) Chin-Kuo Chang et al.   PLoS One

Smoking Characteristics of Adults With Selected Lifetime Mental Illnesses: Results From the 2007 National Health Interview Survey

(2010) Annette K. McClave et al.   AMERICAN JOURNAL OF PUBLIC HEALTH

Psychological Distress is Associated with Tobacco Smoking and Quitting Behaviour in the Australian Population: Evidence from National Cross-Sectional Surveys

(2010) Janni Leung et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

(2010)   NATURE GENETICS

Nicotine Addiction

(2010) Neal L. Benowitz   NEW ENGLAND JOURNAL OF MEDICINE

Smoking and mental illness: results from population surveys in Australia and the United States

(2009) David Lawrence et al.   BMC PUBLIC HEALTH

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

(2008) Thorgeir E. Thorgeirsson et al.   NATURE

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

(2007) Debbie A. Lawlor et al.   STATISTICS IN MEDICINE