Bottleneck and selection in the germline and maternal age influence transmission of mitochondrial DNA in human pedigrees

No further evidence for paternal leakage of mitochondrial DNA in humans yet

(2019) Sabine Lutz-Bonengel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Germline selection shapes human mitochondrial DNA diversity

(2019) Wei Wei et al.   SCIENCE

The mitochondrial DNA genetic bottleneck: inheritance and beyond

(2018) Haixin Zhang et al.   Essays in Biochemistry

A Population Phylogenetic View of Mitochondrial Heteroplasmy

(2018) Peter R. Wilton et al.   GENETICS

Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos

(2018) Vasileios I. Floros et al.   NATURE CELL BIOLOGY

Accurate estimation of 5-methylcytosine in mammalian mitochondrial DNA

(2018) Shigeru Matsuda et al.   Scientific Reports

A Population Phylogenetic View of Mitochondrial Heteroplasmy

(2018) Peter R. Wilton et al.   GENETICS

Biparental Inheritance of Mitochondrial DNA in Humans

(2018) Shiyu Luo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fast and robust detection of ancestral selective sweeps

(2017) Xiaoheng Cheng et al.   MOLECULAR ECOLOGY

Transmission of human mtDNA heteroplasmy in the Genome of the Netherlands families: support for a variable-size bottleneck

(2016) Mingkun Li et al.   GENOME RESEARCH

Mitochondrial DNA sequence characteristics modulate the size of the genetic bottleneck

(2016) Ian J. Wilson et al.   HUMAN MOLECULAR GENETICS

New observations on maternal age effect on germline de novo mutations

(2016) Wendy S. W. Wong et al.   Nature Communications

Controlling for contamination in re-sequencing studies with a reproducible web-based phylogenetic approach

(2016) Benjamin Dickins et al.   BIOTECHNIQUES

Mitochondrial disease: genetics and management

(2015) Yi Shiau Ng et al.   JOURNAL OF NEUROLOGY

The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease

(2015) James B. Stewart et al.   NATURE REVIEWS GENETICS

Extensive tissue-related and allele-related mtDNA heteroplasmy suggests positive selection for somatic mutations

(2015) Mingkun Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stochastic modelling, Bayesian inference, and new in vivo measurements elucidate the debated mtDNA bottleneck mechanism

(2015) Iain G Johnston et al.   eLife

Whole-genome sequence variation, population structure and demographic history of the Dutch population

(2014) Laurent C Francioli et al.   NATURE GENETICS

Control of mitochondrial integrity in ageing and disease

(2014) R. Szklarczyk et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Maternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA

(2014) B. Rebolledo-Jaramillo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estimating and interpreting FST: The impact of rare variants

(2013) G. Bhatia et al.   GENOME RESEARCH

The Mitochondrial Nucleoid: Integrating Mitochondrial DNA into Cellular Homeostasis

(2013) R. Gilkerson et al.   Cold Spring Harbor Perspectives in Biology

Ultra-Sensitive Sequencing Reveals an Age-Related Increase in Somatic Mitochondrial Mutations That Are Inconsistent with Oxidative Damage

(2013) Scott R. Kennedy et al.   PLoS Genetics

Rate of de novo mutations and the importance of father’s age to disease risk

(2012) Augustine Kong et al.   NATURE

Population genetics of the cytoplasm and the units of selection on mitochondrial DNA in Drosophila melanogaster

(2011) David M. Rand   GENETICA

Sequencing of 50 Human Exomes Reveals Adaptation to High Altitude

(2010) X. Yi et al.   SCIENCE

Transmission of Mitochondrial DNA Diseases and Ways to Prevent Them

(2010) Joanna Poulton et al.   PLoS Genetics

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Modelling mitochondrial site polymorphisms to infer the number of segregating units and mutation rate

(2009) M. D. Hendy et al.   Biology Letters

New Evidence Confirms That the Mitochondrial Bottleneck Is Generated without Reduction of Mitochondrial DNA Content in Early Primordial Germ Cells of Mice

(2009) Liqin Cao et al.   PLoS Genetics

Pathogenic Mitochondrial DNA Mutations Are Common in the General Population

(2008) Hannah R. Elliott et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes

(2008) Timothy Wai et al.   NATURE GENETICS

A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes

(2008) Lynsey M Cree et al.   NATURE GENETICS

Mutation and Evolutionary Rates in Adélie Penguins from the Antarctic

(2008) Craig D. Millar et al.   PLoS Genetics