Ribosome assembly defects subvert initiation Factor3 mediated scrutiny of bona fide start signal

Translation initiation factor IF2 contributes to ribosome assembly and maturation during cold adaptation

(2019) Anna Brandi et al.   NUCLEIC ACIDS RESEARCH

The RNA‐binding protein Hfq is important for ribosome biogenesis and affects translation fidelity

(2018) José M Andrade et al.   EMBO JOURNAL

Characterization of 16S rRNA Processing with Pre-30S Subunit Assembly Intermediates from E. coli

(2018) Brian A. Smith et al.   JOURNAL OF MOLECULAR BIOLOGY

The essential nature of YqfG, a YbeY homologue required for 3′ maturation of Bacillus subtilis 16S ribosomal RNA is suppressed by deletion of RNase R

(2018) Kathrin Baumgardt et al.   NUCLEIC ACIDS RESEARCH

Complementary charge-based interaction between the ribosomal-stalk protein L7/12 and IF2 is the key to rapid subunit association

(2018) Xueliang Ge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Slowdown of Translational Elongation in Escherichia coli under Hyperosmotic Stress

(2018) Xiongfeng Dai et al.   mBio

Translation complex profile sequencing to study the in vivo dynamics of mRNA–ribosome interactions during translation initiation, elongation and termination

(2017) Nikolay E Shirokikh et al.   Nature Protocols

RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket

(2017) Jorge Pedro López-Alonso et al.   NUCLEIC ACIDS RESEARCH

Measurements of translation initiation from all 64 codons in E. coli

(2017) Ariel Hecht et al.   NUCLEIC ACIDS RESEARCH

Structure and dynamics of bacterial ribosome biogenesis

(2017) Joseph H. Davis et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Conserved GTPase LepA (Elongation Factor 4) functions in biogenesis of the 30S subunit of the 70S ribosome

(2017) Michelle R. Gibbs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cryo-EM structure of YjeQ bound to the 30S subunit suggests a fidelity checkpoint function for this protein in ribosome assembly

(2017) Aida Razi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ribosomopathies: There’s strength in numbers

(2017) Eric W. Mills et al.   SCIENCE

Optimality and sub-optimality in a bacterial growth law

(2017) Benjamin D. Towbin et al.   Nature Communications

Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation

(2016) Tanweer Hussain et al.   CELL

Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome

(2016) Veerendra Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamics of ribosome scanning and recycling revealed by translation complex profiling

(2016) Stuart K. Archer et al.   NATURE

An evolutionarily conserved element in initiator tRNAs prompts ultimate steps in ribosome maturation

(2016) Sunil Shetty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Context-specific inhibition of translation by ribosomal antibiotics targeting the peptidyl transferase center

(2016) James Marks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduction of translating ribosomes enables Escherichia coli to maintain elongation rates during slow growth

(2016) Xiongfeng Dai et al.   Nature Microbiology

16S rRNA methyltransferase KsgA contributes to oxidative stress resistance and virulence in Staphylococcus aureus

(2015) Tatsuhiko Kyuma et al.   BIOCHIMIE

Toward a Whole-Cell Model of Ribosome Biogenesis: Kinetic Modeling of SSU Assembly

(2015) Tyler M. Earnest et al.   BIOPHYSICAL JOURNAL

Initiation of mRNA translation in bacteria: structural and dynamic aspects

(2015) Claudio O. Gualerzi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ribosomopathies: how a common root can cause a tree of pathologies

(2015) Nadia Danilova et al.   Disease Models & Mechanisms

Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly

(2015) Yury S Polikanov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Twenty years of bacterial RNases and RNA processing: how we've matured

(2015) Murray P. Deutscher   RNA

Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly

(2015) Yury S Polikanov et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Pseudouridine: Still mysterious, but never a fake (uridine)!

(2015) Felix Spenkuch et al.   RNA Biology

Validation of a fluorescence-based screening concept to identify ribosome assembly defects inEscherichia coli

(2014) Rainer Nikolay et al.   NUCLEIC ACIDS RESEARCH

The conserved GTPase LepA contributes mainly to translation initiation in Escherichia coli

(2014) Rohan Balakrishnan et al.   NUCLEIC ACIDS RESEARCH

Functional Interaction between Ribosomal Protein L6 and RbgA during Ribosome Assembly

(2014) Megha Gulati et al.   PLoS Genetics

Structural insights into the assembly of the 30S ribosomal subunit in vivo: functional role of S5 and location of the 17S rRNA precursor sequence

(2014) Zhixiu Yang et al.   Protein & Cell

Distinct stages of the translation elongation cycle revealed by sequencing ribosome-protected mRNA fragments

(2014) Liana F Lareau et al.   eLife

Multiple Exoribonucleases Catalyze Maturation of the 3′ Terminus of 16S Ribosomal RNA (rRNA)

(2013) Shaheen Sulthana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Intermediates and Folding Events in the Early Assembly of the Ribosomal Small Subunit

(2013) Jonathan Lai et al.   JOURNAL OF PHYSICAL CHEMISTRY B

In Vivo X-Ray Footprinting of Pre-30S Ribosomes Reveals Chaperone-Dependent Remodeling of Late Assembly Intermediates

(2013) Sarah F. Clatterbuck Soper et al.   MOLECULAR CELL

Overexpression of RbfA in the absence of the KsgA checkpoint results in impaired translation initiation

(2013) Keith Connolly et al.   MOLECULAR MICROBIOLOGY

Conformational selection of translation initiation factor 3 signals proper substrate selection

(2013) Margaret M Elvekrog et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Involvement of protein IF2 N domain in ribosomal subunit joining revealed from architecture and function of the full-length initiation factor

(2013) A. Simonetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

A Translation-Like Cycle Is a Quality Control Checkpoint for Maturing 40S Ribosome Subunits

(2012) Bethany S. Strunk et al.   CELL

Structural Insights into Methyltransferase KsgA Function in 30S Ribosomal Subunit Biogenesis

(2012) Daniel Boehringer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Real-time assembly landscape of bacterial 30S translation initiation complex

(2012) Pohl Milón et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role of helix 44 of 16S rRNA in the fidelity of translation initiation

(2012) D. Qin et al.   RNA

Assembly of Bacterial Ribosomes

(2011) Zahra Shajani et al.   Annual Review of Biochemistry

rRNA Pseudouridylation Defects Affect Ribosomal Ligand Binding and Translational Fidelity from Yeast to Human Cells

(2011) Karen Jack et al.   MOLECULAR CELL

The Cryo-EM Structure of a Complete 30S Translation Initiation Complex from Escherichia coli

(2011) Patricia Julián et al.   PLOS BIOLOGY

RsgA releases RbfA from 30S ribosome during a late stage of ribosome biosynthesis

(2010) Simon Goto et al.   EMBO JOURNAL

The ribosome-bound initiation factor 2 recruits initiator tRNA to the 30S initiation complex

(2010) Pohl Milon et al.   EMBO REPORTS

When ribosomes go bad: diseases of ribosome biogenesis

(2010) Emily F. Freed et al.   Molecular BioSystems

Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function

(2010) H. Demirci et al.   RNA

Role of GTPases in Bacterial Ribosome Assembly

(2009) Robert A. Britton   Annual Review of Microbiology

Bases in 16S rRNA Important for Subunit Association, tRNA Binding, and Translocation

(2009) Xinying Shi et al.   BIOCHEMISTRY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Control of translation initiation involves a factor-induced rearrangement of helix 44 of 16S ribosomal RNA

(2009) Daoming Qin et al.   MOLECULAR MICROBIOLOGY

Erythromycin- and Chloramphenicol-Induced Ribosomal Assembly Defects Are Secondary Effects of Protein Synthesis Inhibition

(2008) T. Siibak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Kinetic Checkpoint at a Late Step in Translation Initiation

(2008) Pohl Milon et al.   MOLECULAR CELL

Mechanistic insight into the ribosome biogenesis functions of the ancient protein KsgA

(2008) Keith Connolly et al.   MOLECULAR MICROBIOLOGY

Structure of the 30S translation initiation complex

(2008) Angelita Simonetti et al.   NATURE

A conserved rRNA methyltransferase regulates ribosome biogenesis

(2008) Zhili Xu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY