The mutational footprints of cancer therapies

The Clonal Evolution of Metastatic Osteosarcoma as Shaped by Cisplatin Treatment

(2019) Samuel W. Brady et al.   MOLECULAR CANCER RESEARCH

A Compendium of Mutational Signatures of Environmental Agents

(2019) Jill E. Kucab et al.   CELL

In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors

(2018) Arnoud Boot et al.   GENOME RESEARCH

Somatic and Germline Mutation Periodicity Follow the Orientation of the DNA Minor Groove around Nucleosomes

(2018) Oriol Pich et al.   CELL

Structural basis for the initiation of eukaryotic transcription-coupled DNA repair

(2017) Jun Xu et al.   NATURE

Hypermutation signature reveals a slippage and realignment model of translesion synthesis by Rev3 polymerase in cisplatin-treated yeast

(2017) Romulo Segovia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair

(2016) Nicholas J. Haradhvala et al.   CELL

Somatic ERCC2 mutations are associated with a distinct genomic signature in urothelial tumors

(2016) Jaegil Kim et al.   NATURE GENETICS

Clonal evolution of glioblastoma under therapy

(2016) Jiguang Wang et al.   NATURE GENETICS

Mutational signatures associated with tobacco smoking in human cancer

(2016) L. B. Alexandrov et al.   SCIENCE

The topography of mutational processes in breast cancer genomes

(2016) Sandro Morganella et al.   Nature Communications

Mutational signatures of ionizing radiation in second malignancies

(2016) Sam Behjati et al.   Nature Communications

Chemotherapy-only treatment effects on long-term neurocognitive functioning in childhood ALL survivors: a review and meta-analysis

(2015) N. S. Iyer et al.   BLOOD

Clock-like mutational processes in human somatic cells

(2015) Ludmil B Alexandrov et al.   NATURE GENETICS

Cancer-treatment-induced neurotoxicity—focus on newer treatments

(2015) Jacqueline B. Stone et al.   Nature Reviews Clinical Oncology

Breast cancer therapy-associated cardiovascular disease

(2015) Timothy M. Zagar et al.   Nature Reviews Clinical Oncology

Somatic mutation in cancer and normal cells

(2015) I. Martincorena et al.   SCIENCE

Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution

(2015) S. Kasar et al.   Nature Communications

Secondary malignancies in pediatric cancer survivors: Perspectives and review of the literature

(2014) Daniel K. Choi et al.   INTERNATIONAL JOURNAL OF CANCER

Mechanisms underlying mutational signatures in human cancers

(2014) Thomas Helleday et al.   NATURE REVIEWS GENETICS

Signatures of mutational processes in human cancer

(2013) Ludmil B. Alexandrov et al.   NATURE

Treatment-related cardiotoxicity in survivors of childhood cancer

(2013) Steven E. Lipshultz et al.   Nature Reviews Clinical Oncology

Deciphering Signatures of Mutational Processes Operative in Human Cancer

(2013) Ludmil B. Alexandrov et al.   Cell Reports

Gene Amplification and Point Mutations in Pyrimidine Metabolic Genes in 5-Fluorouracil Resistant Leishmania infantum

(2013) Jean-François Ritt et al.   PLoS Neglected Tropical Diseases

Late Effects in Adult Survivors of Pediatric Cancer: A Guide for the Primary Care Physician

(2012) Lisa M. Kopp et al.   AMERICAN JOURNAL OF MEDICINE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects

(2011) Ana-Maria Florea et al.   Cancers

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Participation of DNA repair in the response to 5-fluorouracil

(2008) M. D. Wyatt et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Transcription-coupled DNA repair: two decades of progress and surprises

(2008) Philip C. Hanawalt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY