Gene Amplification and Point Mutations in Pyrimidine Metabolic Genes in 5-Fluorouracil Resistant Leishmania infantum

Folate metabolic pathways inLeishmania

(2015) Tim J. Vickers et al.   Essays in Biochemistry

Pyrimidine Biosynthesis Is Not an Essential Function for Trypanosoma brucei Bloodstream Forms

(2013) Juma A. M. Ali et al.   PLoS One

Leishmaniasis: an update of current pharmacotherapy

(2012) Shyam Sundar et al.   EXPERT OPINION ON PHARMACOTHERAPY

Genetic Dissection of Pyrimidine Biosynthesis and Salvage inLeishmania donovani

(2012) Zachary N. Wilson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leishmaniasis: Current status of available drugs and new potential drug targets

(2012) Nisha Singh et al.   Asian Pacific Journal of Tropical Medicine

Multiple Mutations in Heterogeneous Miltefosine-Resistant Leishmania major Population as Determined by Whole Genome Sequencing

(2012) Adriano C. Coelho et al.   PLoS Neglected Tropical Diseases

Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance

(2011) T. Downing et al.   GENOME RESEARCH

SAMStat: monitoring biases in next generation sequencing data

(2010) T. Lassmann et al.   BIOINFORMATICS

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

High AffinityS-Adenosylmethionine Plasma Membrane Transporter ofLeishmaniaIs a Member of the Folate Biopterin Transporter (FBT) Family

(2010) Larbi Dridi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Gene expression modulation is associated with gene amplification, supernumerary chromosomes and chromosome loss in antimony-resistant Leishmania infantum

(2009) P. Leprohon et al.   NUCLEIC ACIDS RESEARCH

TriTrypDB: a functional genomic resource for the Trypanosomatidae

(2009) Martin Aslett et al.   NUCLEIC ACIDS RESEARCH

The RNA Exosome Component hRrp6 Is a Target for 5-Fluorouracil in Human Cells

(2008) S. Kammler et al.   MOLECULAR CANCER RESEARCH

5-Fluorouracil: Mechanisms of Resistance and Reversal Strategies

(2008) Ning Zhang et al.   MOLECULES

Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy

(2008) Jean-Michel Ubeda et al.   GENOME BIOLOGY